HRP20090459T1 - Aminofenil derivati kao novi inhibitori histonskih deacetilaza - Google Patents

Aminofenil derivati kao novi inhibitori histonskih deacetilaza Download PDF

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Publication number
HRP20090459T1
HRP20090459T1 HR20090459T HRP20090459T HRP20090459T1 HR P20090459 T1 HRP20090459 T1 HR P20090459T1 HR 20090459 T HR20090459 T HR 20090459T HR P20090459 T HRP20090459 T HR P20090459T HR P20090459 T1 HRP20090459 T1 HR P20090459T1
Authority
HR
Croatia
Prior art keywords
6alkyl
hydrogen
amino
compound
compound according
Prior art date
Application number
HR20090459T
Other languages
English (en)
Croatian (hr)
Inventor
Ren� Angibaud Patrick
No�lle Constance Pilatte Isabelle
Roux Bruno
Arts Janine
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HRP20090459T1 publication Critical patent/HRP20090459T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HR20090459T 2006-01-19 2007-01-16 Aminofenil derivati kao novi inhibitori histonskih deacetilaza HRP20090459T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06100584 2006-01-19
PCT/EP2007/050376 WO2007082878A1 (en) 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase

Publications (1)

Publication Number Publication Date
HRP20090459T1 true HRP20090459T1 (hr) 2009-09-30

Family

ID=36579211

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090459T HRP20090459T1 (hr) 2006-01-19 2007-01-16 Aminofenil derivati kao novi inhibitori histonskih deacetilaza

Country Status (18)

Country Link
US (1) US8119650B2 (enExample)
EP (1) EP1981874B1 (enExample)
JP (1) JP5225104B2 (enExample)
CN (1) CN101370804B (enExample)
AT (1) ATE432272T1 (enExample)
AU (1) AU2007206946B2 (enExample)
CA (1) CA2631876C (enExample)
CY (1) CY1109331T1 (enExample)
DE (1) DE602007001190D1 (enExample)
DK (1) DK1981874T3 (enExample)
ES (1) ES2327972T3 (enExample)
HR (1) HRP20090459T1 (enExample)
ME (1) ME01060B (enExample)
PL (1) PL1981874T3 (enExample)
PT (1) PT1981874E (enExample)
RS (1) RS51191B (enExample)
SI (1) SI1981874T1 (enExample)
WO (1) WO2007082878A1 (enExample)

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WO2003076400A1 (en) 2002-03-13 2003-09-18 Janssen Pharmaceutica N.V. New inhibitors of histone deacetylase
HRP20040804A2 (en) 2002-03-13 2005-02-28 Janssen Pharmaceutica N.V. Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase
CN100503599C (zh) 2002-03-13 2009-06-24 詹森药业有限公司 作为组蛋白脱乙酰酶的新颖抑制剂的羰基氨基衍生物
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EP1885710B1 (en) 2005-05-18 2015-08-19 Janssen Pharmaceutica N.V. Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase
EP1943232B1 (en) * 2005-10-27 2011-05-18 Janssen Pharmaceutica NV Squaric acid derivatives as inhibitors of histone deacetylase
ES2396986T3 (es) * 2006-01-19 2013-03-01 Janssen Pharmaceutica N.V. Derivados de piridina y pirimidina como inhibidores de histona desacetilasa
CA2635015C (en) 2006-01-19 2014-06-03 Janssen Pharmaceutica N.V. Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
EP1979328B1 (en) * 2006-01-19 2012-12-26 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
US8101616B2 (en) 2006-01-19 2012-01-24 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
PT1981874E (pt) 2006-01-19 2009-09-02 Janssen Pharmactuica N V Derivados de aminofenil como novos inibidores de histonadesacetilase
ES2395347T3 (es) 2008-03-27 2013-02-12 Janssen Pharmaceutica, N.V. Derivados de indolilalquilamino sustituidos con aza-biciclohexilo como inhibidores novedosos de histona desacetilasa
CN102118969B (zh) 2008-06-12 2017-03-08 詹森药业有限公司 组胺h4受体的二氨基吡啶、二氨基嘧啶和二氨基哒嗪调节剂
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Also Published As

Publication number Publication date
CN101370804A (zh) 2009-02-18
EP1981874B1 (en) 2009-05-27
US20090018152A1 (en) 2009-01-15
EP1981874A1 (en) 2008-10-22
RS51191B (sr) 2010-10-31
HK1128283A1 (en) 2009-10-23
ATE432272T1 (de) 2009-06-15
JP2009523760A (ja) 2009-06-25
ES2327972T3 (es) 2009-11-05
PT1981874E (pt) 2009-09-02
PL1981874T3 (pl) 2009-10-30
CN101370804B (zh) 2013-05-29
ME01060B (me) 2012-10-20
AU2007206946A1 (en) 2007-07-26
DE602007001190D1 (de) 2009-07-09
SI1981874T1 (sl) 2009-10-31
CY1109331T1 (el) 2014-07-02
US8119650B2 (en) 2012-02-21
AU2007206946B2 (en) 2011-12-15
CA2631876A1 (en) 2007-07-26
WO2007082878A1 (en) 2007-07-26
CA2631876C (en) 2014-05-27
DK1981874T3 (da) 2009-09-28
JP5225104B2 (ja) 2013-07-03

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