RS51191B - Derivati aminofenila kao novi inhibitori histon deacetilaze - Google Patents

Derivati aminofenila kao novi inhibitori histon deacetilaze

Info

Publication number
RS51191B
RS51191B RSP-2009/0384A RSP20090384A RS51191B RS 51191 B RS51191 B RS 51191B RS P20090384 A RSP20090384 A RS P20090384A RS 51191 B RS51191 B RS 51191B
Authority
RS
Serbia
Prior art keywords
alkyl
hydrogen
6alkyl
amino
compound
Prior art date
Application number
RSP-2009/0384A
Other languages
English (en)
Serbian (sr)
Inventor
Patrick René Angibaud
Isabelle Noëlle Constance PILATTE
Bruno Roux
Janine Arts
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of RS51191B publication Critical patent/RS51191B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RSP-2009/0384A 2006-01-19 2007-01-16 Derivati aminofenila kao novi inhibitori histon deacetilaze RS51191B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06100584 2006-01-19
PCT/EP2007/050376 WO2007082878A1 (en) 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase

Publications (1)

Publication Number Publication Date
RS51191B true RS51191B (sr) 2010-10-31

Family

ID=36579211

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2009/0384A RS51191B (sr) 2006-01-19 2007-01-16 Derivati aminofenila kao novi inhibitori histon deacetilaze

Country Status (18)

Country Link
US (1) US8119650B2 (enExample)
EP (1) EP1981874B1 (enExample)
JP (1) JP5225104B2 (enExample)
CN (1) CN101370804B (enExample)
AT (1) ATE432272T1 (enExample)
AU (1) AU2007206946B2 (enExample)
CA (1) CA2631876C (enExample)
CY (1) CY1109331T1 (enExample)
DE (1) DE602007001190D1 (enExample)
DK (1) DK1981874T3 (enExample)
ES (1) ES2327972T3 (enExample)
HR (1) HRP20090459T1 (enExample)
ME (1) ME01060B (enExample)
PL (1) PL1981874T3 (enExample)
PT (1) PT1981874E (enExample)
RS (1) RS51191B (enExample)
SI (1) SI1981874T1 (enExample)
WO (1) WO2007082878A1 (enExample)

Families Citing this family (23)

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ATE398615T1 (de) 2002-03-13 2008-07-15 Janssen Pharmaceutica Nv Piperazinyl-, piperidinyl- und morpholinylderivate als neue inhibitoren von histon-deacetylase
BR0307607A (pt) 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Derivados de carbonilamino como inibidores de histona desacetilase
EP1485354B1 (en) 2002-03-13 2008-05-28 Janssen Pharmaceutica N.V. Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
JP4725944B2 (ja) 2002-03-13 2011-07-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの阻害剤
UA86066C2 (ru) * 2004-07-28 2009-03-25 Янссен Фармацевтика Н.В. Производные замещенного пропенилпиперазина как ингибиторы гистондеацетилазы
EA010652B1 (ru) * 2004-07-28 2008-10-30 Янссен Фармацевтика Н.В. Замещенные индолильные алкиламинопроизводные в качестве новых ингибиторов гистондеацетилазы
JP5055268B2 (ja) 2005-05-18 2012-10-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの新規な阻害剤としての置換されたアミノプロペニルピペリジンまたはモルホリン誘導体
CA2623360C (en) * 2005-10-27 2014-04-22 Janssen Pharmaceutica N.V. Squaric acid derivatives as inhibitors of histone deacetylase
CN101370789B (zh) 2006-01-19 2012-05-30 詹森药业有限公司 作为组蛋白脱乙酰酶抑制剂的吡啶和嘧啶衍生物
RS51191B (sr) 2006-01-19 2010-10-31 Janssen Pharmaceutica N.V. Derivati aminofenila kao novi inhibitori histon deacetilaze
CA2630717C (en) 2006-01-19 2015-02-24 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
CN101370791B (zh) * 2006-01-19 2012-05-02 詹森药业有限公司 作为组蛋白脱乙酰基酶抑制剂的吡啶和嘧啶衍生物
US7834025B2 (en) * 2006-01-19 2010-11-16 Janssen Pharmaceutica N.V. Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
DK2274301T3 (da) 2008-03-27 2013-01-02 Janssen Pharmaceutica Nv Azabicyclohexylsubstituerede indolylalkylaminoderivater som hidtil ukendte inhibitorer af histondeacetylase
BRPI0915720A2 (pt) * 2008-06-12 2015-08-04 Janssen Pharmaceutica Nv Moduladores de diaminopiridina, pirimidina, e piridazina do receptor de histamina h4
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CN103648492A (zh) 2011-03-09 2014-03-19 赛伦诺科学有限公司 利用组蛋白脱乙酰酶抑制物改善受损的内源纤维蛋白溶解作用的化合物和方法
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CN101370791B (zh) 2006-01-19 2012-05-02 詹森药业有限公司 作为组蛋白脱乙酰基酶抑制剂的吡啶和嘧啶衍生物
CN101370789B (zh) 2006-01-19 2012-05-30 詹森药业有限公司 作为组蛋白脱乙酰酶抑制剂的吡啶和嘧啶衍生物
RS51191B (sr) 2006-01-19 2010-10-31 Janssen Pharmaceutica N.V. Derivati aminofenila kao novi inhibitori histon deacetilaze
CN101516375B (zh) 2006-09-15 2012-10-03 詹森药业有限公司 类别-i具体组织蛋白脱乙酰基酶抑制剂与蛋白酶体抑制剂的组合
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Also Published As

Publication number Publication date
SI1981874T1 (sl) 2009-10-31
CA2631876A1 (en) 2007-07-26
HRP20090459T1 (hr) 2009-09-30
PT1981874E (pt) 2009-09-02
WO2007082878A1 (en) 2007-07-26
DE602007001190D1 (de) 2009-07-09
AU2007206946A1 (en) 2007-07-26
ATE432272T1 (de) 2009-06-15
CY1109331T1 (el) 2014-07-02
HK1128283A1 (en) 2009-10-23
EP1981874B1 (en) 2009-05-27
EP1981874A1 (en) 2008-10-22
US8119650B2 (en) 2012-02-21
PL1981874T3 (pl) 2009-10-30
JP5225104B2 (ja) 2013-07-03
ES2327972T3 (es) 2009-11-05
CN101370804A (zh) 2009-02-18
US20090018152A1 (en) 2009-01-15
JP2009523760A (ja) 2009-06-25
CN101370804B (zh) 2013-05-29
CA2631876C (en) 2014-05-27
DK1981874T3 (da) 2009-09-28
ME01060B (me) 2012-10-20
AU2007206946B2 (en) 2011-12-15

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