AU2007206946B2 - Aminophenyl derivatives as novel inhibitors of histone deacetylase - Google Patents

Aminophenyl derivatives as novel inhibitors of histone deacetylase Download PDF

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Publication number
AU2007206946B2
AU2007206946B2 AU2007206946A AU2007206946A AU2007206946B2 AU 2007206946 B2 AU2007206946 B2 AU 2007206946B2 AU 2007206946 A AU2007206946 A AU 2007206946A AU 2007206946 A AU2007206946 A AU 2007206946A AU 2007206946 B2 AU2007206946 B2 AU 2007206946B2
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AU
Australia
Prior art keywords
compound
alkyl
hydrogen
compounds
formula
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Ceased
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AU2007206946A
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AU2007206946A1 (en
Inventor
Patrick Rene Angibaud
Janine Arts
Isabelle Noelle Constance Pilatte
Bruno Roux
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Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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Publication of AU2007206946A1 publication Critical patent/AU2007206946A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
AU2007206946A 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase Ceased AU2007206946B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06100584.9 2006-01-19
EP06100584 2006-01-19
PCT/EP2007/050376 WO2007082878A1 (en) 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase

Publications (2)

Publication Number Publication Date
AU2007206946A1 AU2007206946A1 (en) 2007-07-26
AU2007206946B2 true AU2007206946B2 (en) 2011-12-15

Family

ID=36579211

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007206946A Ceased AU2007206946B2 (en) 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase

Country Status (18)

Country Link
US (1) US8119650B2 (enExample)
EP (1) EP1981874B1 (enExample)
JP (1) JP5225104B2 (enExample)
CN (1) CN101370804B (enExample)
AT (1) ATE432272T1 (enExample)
AU (1) AU2007206946B2 (enExample)
CA (1) CA2631876C (enExample)
CY (1) CY1109331T1 (enExample)
DE (1) DE602007001190D1 (enExample)
DK (1) DK1981874T3 (enExample)
ES (1) ES2327972T3 (enExample)
HR (1) HRP20090459T1 (enExample)
ME (1) ME01060B (enExample)
PL (1) PL1981874T3 (enExample)
PT (1) PT1981874E (enExample)
RS (1) RS51191B (enExample)
SI (1) SI1981874T1 (enExample)
WO (1) WO2007082878A1 (enExample)

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CA2476583C (en) 2002-03-13 2011-07-05 Kristof Van Emelen Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase
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ME01058B (me) * 2004-07-28 2012-10-20 Janssen Pharmaceutica Nv Supstituisani derivati propenil piperazina kao novi inhibitori histonske deacetilaze
DK1885710T3 (en) 2005-05-18 2015-11-23 Janssen Pharmaceutica Nv SUBSTITUTED AMINOPROPENYLPIPERIDINE OR MORPHOLINE DERIVATIVES AS UNKNOWN INHIBITORS OF HISTONDEACETYLASE
CA2623360C (en) * 2005-10-27 2014-04-22 Janssen Pharmaceutica N.V. Squaric acid derivatives as inhibitors of histone deacetylase
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US7888360B2 (en) * 2006-01-19 2011-02-15 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
DK1981875T3 (da) * 2006-01-19 2014-07-14 Janssen Pharmaceutica Nv Substituerede indolylalkylaminoderivater som inhibitorer af histondeacetylase
EP1979326B1 (en) 2006-01-19 2012-10-03 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
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Also Published As

Publication number Publication date
ME01060B (me) 2012-10-20
EP1981874A1 (en) 2008-10-22
CY1109331T1 (el) 2014-07-02
RS51191B (sr) 2010-10-31
WO2007082878A1 (en) 2007-07-26
JP5225104B2 (ja) 2013-07-03
DE602007001190D1 (de) 2009-07-09
CA2631876C (en) 2014-05-27
CA2631876A1 (en) 2007-07-26
ES2327972T3 (es) 2009-11-05
CN101370804A (zh) 2009-02-18
EP1981874B1 (en) 2009-05-27
US8119650B2 (en) 2012-02-21
CN101370804B (zh) 2013-05-29
JP2009523760A (ja) 2009-06-25
HK1128283A1 (en) 2009-10-23
US20090018152A1 (en) 2009-01-15
SI1981874T1 (sl) 2009-10-31
DK1981874T3 (da) 2009-09-28
HRP20090459T1 (hr) 2009-09-30
PT1981874E (pt) 2009-09-02
PL1981874T3 (pl) 2009-10-30
AU2007206946A1 (en) 2007-07-26
ATE432272T1 (de) 2009-06-15

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