DE602007001190D1 - Aminophenylderivate als neue inhibitoren von histondeacetylase - Google Patents

Aminophenylderivate als neue inhibitoren von histondeacetylase

Info

Publication number
DE602007001190D1
DE602007001190D1 DE602007001190T DE602007001190T DE602007001190D1 DE 602007001190 D1 DE602007001190 D1 DE 602007001190D1 DE 602007001190 T DE602007001190 T DE 602007001190T DE 602007001190 T DE602007001190 T DE 602007001190T DE 602007001190 D1 DE602007001190 D1 DE 602007001190D1
Authority
DE
Germany
Prior art keywords
histondeacetylase
new inhibitors
aminophenyl derivatives
aminophenyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007001190T
Other languages
German (de)
English (en)
Inventor
Patrick Rene Angibaud
Isabelle Noelle Pilatte
Bruno Roux
Janine Arts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE602007001190D1 publication Critical patent/DE602007001190D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
DE602007001190T 2006-01-19 2007-01-16 Aminophenylderivate als neue inhibitoren von histondeacetylase Active DE602007001190D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06100584 2006-01-19
PCT/EP2007/050376 WO2007082878A1 (en) 2006-01-19 2007-01-16 Aminophenyl derivatives as novel inhibitors of histone deacetylase

Publications (1)

Publication Number Publication Date
DE602007001190D1 true DE602007001190D1 (de) 2009-07-09

Family

ID=36579211

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007001190T Active DE602007001190D1 (de) 2006-01-19 2007-01-16 Aminophenylderivate als neue inhibitoren von histondeacetylase

Country Status (18)

Country Link
US (1) US8119650B2 (enExample)
EP (1) EP1981874B1 (enExample)
JP (1) JP5225104B2 (enExample)
CN (1) CN101370804B (enExample)
AT (1) ATE432272T1 (enExample)
AU (1) AU2007206946B2 (enExample)
CA (1) CA2631876C (enExample)
CY (1) CY1109331T1 (enExample)
DE (1) DE602007001190D1 (enExample)
DK (1) DK1981874T3 (enExample)
ES (1) ES2327972T3 (enExample)
HR (1) HRP20090459T1 (enExample)
ME (1) ME01060B (enExample)
PL (1) PL1981874T3 (enExample)
PT (1) PT1981874E (enExample)
RS (1) RS51191B (enExample)
SI (1) SI1981874T1 (enExample)
WO (1) WO2007082878A1 (enExample)

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US7501417B2 (en) 2002-03-13 2009-03-10 Janssen Pharmaceutica, N.V. Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase
DE60321667D1 (en) * 2002-03-13 2008-07-31 Janssen Pharmaceutica Nv Piperazinyl-, piperidinyl- und morpholinylderivate als neue inhibitoren von histon-deacetylase
UA86066C2 (ru) * 2004-07-28 2009-03-25 Янссен Фармацевтика Н.В. Производные замещенного пропенилпиперазина как ингибиторы гистондеацетилазы
PL1781639T3 (pl) * 2004-07-28 2012-07-31 Janssen Pharmaceutica Nv Podstawione pochodne indolilo-alkiloaminowe jako nowe inhibitory deacetylazy histonowej
JP5055268B2 (ja) 2005-05-18 2012-10-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの新規な阻害剤としての置換されたアミノプロペニルピペリジンまたはモルホリン誘導体
JP5070214B2 (ja) * 2005-10-27 2012-11-07 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの阻害剤としてのスクエア酸誘導体
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JP5247470B2 (ja) 2006-01-19 2013-07-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼのインヒビターとしてのピリジン及びピリミジン誘導体
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Also Published As

Publication number Publication date
EP1981874B1 (en) 2009-05-27
RS51191B (sr) 2010-10-31
PT1981874E (pt) 2009-09-02
EP1981874A1 (en) 2008-10-22
CN101370804A (zh) 2009-02-18
ME01060B (me) 2012-10-20
HRP20090459T1 (hr) 2009-09-30
AU2007206946B2 (en) 2011-12-15
PL1981874T3 (pl) 2009-10-30
CA2631876A1 (en) 2007-07-26
US8119650B2 (en) 2012-02-21
CA2631876C (en) 2014-05-27
US20090018152A1 (en) 2009-01-15
AU2007206946A1 (en) 2007-07-26
JP2009523760A (ja) 2009-06-25
CY1109331T1 (el) 2014-07-02
CN101370804B (zh) 2013-05-29
ATE432272T1 (de) 2009-06-15
JP5225104B2 (ja) 2013-07-03
WO2007082878A1 (en) 2007-07-26
SI1981874T1 (sl) 2009-10-31
DK1981874T3 (da) 2009-09-28
ES2327972T3 (es) 2009-11-05
HK1128283A1 (en) 2009-10-23

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