HRP20060362A2 - Method for the purification of albumin conjugates - Google Patents

Method for the purification of albumin conjugates

Info

Publication number
HRP20060362A2
HRP20060362A2 HR20060362A HRP20060362A HRP20060362A2 HR P20060362 A2 HRP20060362 A2 HR P20060362A2 HR 20060362 A HR20060362 A HR 20060362A HR P20060362 A HRP20060362 A HR P20060362A HR P20060362 A2 HRP20060362 A2 HR P20060362A2
Authority
HR
Croatia
Prior art keywords
albumin
albumin conjugates
conjugates
purification
solution
Prior art date
Application number
HR20060362A
Other languages
English (en)
Croatian (hr)
Inventor
Bousquet-Gagnon Nathalie
Quraishi Omar
P. Bridon Dominique
Original Assignee
Conjuchem Biotechnologies Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35196920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20060362(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Conjuchem Biotechnologies Inc. filed Critical Conjuchem Biotechnologies Inc.
Publication of HRP20060362A2 publication Critical patent/HRP20060362A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HR20060362A 2004-04-23 2006-10-23 Method for the purification of albumin conjugates HRP20060362A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56522804P 2004-04-23 2004-04-23
PCT/CA2005/000614 WO2005103087A1 (fr) 2004-04-23 2005-04-22 Procede de purification de conjugues d'albumine

Publications (1)

Publication Number Publication Date
HRP20060362A2 true HRP20060362A2 (en) 2007-03-31

Family

ID=35196920

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20060362A HRP20060362A2 (en) 2004-04-23 2006-10-23 Method for the purification of albumin conjugates

Country Status (25)

Country Link
US (3) US7307148B2 (fr)
EP (3) EP1745078B1 (fr)
JP (1) JP2007535507A (fr)
CN (1) CN1956998B (fr)
AT (2) ATE473244T1 (fr)
AU (1) AU2005235634B2 (fr)
BR (1) BRPI0510117A (fr)
CA (1) CA2564031A1 (fr)
DE (2) DE602005022239D1 (fr)
DK (2) DK1745078T3 (fr)
EA (1) EA011168B1 (fr)
ES (2) ES2347902T3 (fr)
HK (2) HK1096102A1 (fr)
HR (1) HRP20060362A2 (fr)
IL (1) IL178369A0 (fr)
MA (1) MA28587B1 (fr)
MX (1) MXPA06012260A (fr)
NO (1) NO20065037L (fr)
PL (2) PL2100904T3 (fr)
PT (2) PT1745078E (fr)
RS (1) RS20060578A (fr)
SI (2) SI1745078T1 (fr)
TN (1) TNSN06340A1 (fr)
WO (1) WO2005103087A1 (fr)
ZA (1) ZA200608475B (fr)

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US20040266673A1 (en) * 2002-07-31 2004-12-30 Peter Bakis Long lasting natriuretic peptide derivatives
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US20090175821A1 (en) * 1999-05-17 2009-07-09 Bridon Dominique P Modified therapeutic peptides with extended half-lives in vivo
US7112567B2 (en) * 2001-02-16 2006-09-26 Conjuchem Inc. Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders
DE60229677D1 (de) 2001-05-31 2008-12-11 Conjuchem Biotechnologies Inc Langwirkende Fusionspeptidinhibitoren gegen HIV-Infektion
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US8039432B2 (en) 2005-11-09 2011-10-18 Conjuchem, Llc Method of treatment of diabetes and/or obesity with reduced nausea side effect
JP2009520469A (ja) * 2005-12-22 2009-05-28 コンジュクヘム ビオテクフノロギエス インコーポレイテッド アルブミンと治療薬との前もって形成された抱合体の産生のための方法
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MX2020004453A (es) * 2017-09-28 2020-07-24 Hanmi Pharm Ind Co Ltd Conjugados de accion prolongada de derivados de glp-2.
CN108840922A (zh) * 2018-06-04 2018-11-20 河北常山生化药业股份有限公司 分离白蛋白非结合物、白蛋白结合物和小分子化合物的方法
CN108977423A (zh) * 2018-08-17 2018-12-11 集美大学 一种从猪肺中分离提纯血管紧张素转化酶的方法
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CN109721653B (zh) * 2019-03-05 2023-02-03 嘉兴学院 一种胰高血糖素样肽-1片段类似物及其应用
CN115397846A (zh) * 2020-03-06 2022-11-25 昆山新蕴达生物科技有限公司 疏水性修饰的白蛋白及其制备方法和用途
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JP2007535507A (ja) 2007-12-06
SI1745078T1 (sl) 2009-12-31
BRPI0510117A (pt) 2007-09-25
US20120022234A1 (en) 2012-01-26
RS20060578A (en) 2008-11-28
PT1745078E (pt) 2009-09-17
DK1745078T3 (da) 2009-10-26
ATE433999T1 (de) 2009-07-15
DK2100904T3 (da) 2010-11-08
PL2100904T3 (pl) 2011-05-31
ZA200608475B (en) 2007-11-28
EA011168B1 (ru) 2009-02-27
EP1745078A1 (fr) 2007-01-24
ATE473244T1 (de) 2010-07-15
EP1745078B1 (fr) 2009-06-17
AU2005235634A1 (en) 2005-11-03
IL178369A0 (en) 2007-02-11
AU2005235634B2 (en) 2011-10-20
SI2100904T1 (sl) 2010-10-29
MXPA06012260A (es) 2006-12-15
DE602005014969D1 (de) 2009-07-30
ES2328591T3 (es) 2009-11-16
HK1136305A1 (en) 2010-06-25
US20050267293A1 (en) 2005-12-01
US20080146783A1 (en) 2008-06-19
CN1956998A (zh) 2007-05-02
ES2347902T3 (es) 2010-11-22
EP2100904B1 (fr) 2010-07-07
EP2100904A1 (fr) 2009-09-16
HK1096102A1 (en) 2007-05-25
TNSN06340A1 (en) 2008-02-22
CA2564031A1 (fr) 2005-11-03
US7307148B2 (en) 2007-12-11
EA200601959A1 (ru) 2007-04-27
WO2005103087A1 (fr) 2005-11-03
DE602005022239D1 (de) 2010-08-19
PL1745078T3 (pl) 2009-12-31
PT2100904E (pt) 2010-09-24
EP2230257A1 (fr) 2010-09-22
CN1956998B (zh) 2012-12-12
EP1745078A4 (fr) 2007-08-01
MA28587B1 (fr) 2007-05-02

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