HRP20050870A2 - Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter - Google Patents
Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latterInfo
- Publication number
- HRP20050870A2 HRP20050870A2 HR20050870A HRP20050870A HRP20050870A2 HR P20050870 A2 HRP20050870 A2 HR P20050870A2 HR 20050870 A HR20050870 A HR 20050870A HR P20050870 A HRP20050870 A HR P20050870A HR P20050870 A2 HRP20050870 A2 HR P20050870A2
- Authority
- HR
- Croatia
- Prior art keywords
- compound
- production method
- physiological characteristics
- corresponding production
- medicaments containing
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Izum se odnosi na novi difenil azetidinon, na postupak za njegovu proizvodnju, na lijek koji sadržitaj spoj i na njegovu upotrebu. Izum se odnosi naspo] opće formula (I),kao i na njegove fiziološkipodnošljive soli. Ovaj spoj je prikladan npr. kaohipolipidemik.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10314610A DE10314610A1 (de) | 2003-04-01 | 2003-04-01 | Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung |
PCT/EP2004/002690 WO2004087655A1 (de) | 2003-04-01 | 2004-03-16 | Neues diphenylazetidinon mit verbesserten physiologischen eigenschaften, verfahren zu dessen herstellung, diese verbindungen enthaltende arzneimittel und dessen verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20050870A2 true HRP20050870A2 (en) | 2006-10-31 |
Family
ID=33103147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20050870A HRP20050870A2 (en) | 2003-04-01 | 2005-09-30 | Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter |
Country Status (44)
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
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RS50864B (sr) * | 2000-12-21 | 2010-08-31 | Sanofi-Aventis Deutschland Gmbh. | Novi 1,2-difenil-azetidinoni, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena za lečenje poremećaja u metabolizmu lipida |
AU2006262441A1 (en) | 2005-06-20 | 2007-01-04 | Schering Corporation | Piperidine derivatives useful as histamine H3 antagonists |
US7067689B1 (en) | 2005-07-08 | 2006-06-27 | Microbia, Inc. | Process for production of pentahydroxyhexylcarbamoyl alkanoic acids |
RU2009108280A (ru) | 2006-08-08 | 2010-09-20 | Санофи-Авентис (Fr) | Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение |
DE102007029612A1 (de) * | 2007-06-27 | 2009-01-08 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester |
US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
US20080319218A1 (en) * | 2007-06-22 | 2008-12-25 | Andreas Haubrich | Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE102007054497B3 (de) * | 2007-11-13 | 2009-07-23 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung |
JP2011511011A (ja) * | 2008-02-05 | 2011-04-07 | ハーバー バイオサイエンシーズ,インコーポレイテッド | 医薬的固体状態形態 |
DE102008059772A1 (de) | 2008-12-01 | 2010-06-02 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung eines Diphenylazetidinons |
WO2009112203A1 (de) * | 2008-03-14 | 2009-09-17 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur herstellung eines diphenylazetidinons |
DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8809324B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120051A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
US10426480B2 (en) * | 2015-04-29 | 2019-10-01 | Covidien Lp | Cutting ring assembly with rigid cutting member |
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FR2663336B1 (fr) | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5756740A (en) * | 1992-04-08 | 1998-05-26 | Eastman Kodak Company | Process for the preparation of binary sensitizing dyes |
FR2713225B1 (fr) | 1993-12-02 | 1996-03-01 | Sanofi Sa | N-pipéridino-3-pyrazolecarboxamide substitué. |
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US5756470A (en) * | 1996-10-29 | 1998-05-26 | Schering Corporation | Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents |
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RS50864B (sr) * | 2000-12-21 | 2010-08-31 | Sanofi-Aventis Deutschland Gmbh. | Novi 1,2-difenil-azetidinoni, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena za lečenje poremećaja u metabolizmu lipida |
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2003
- 2003-04-01 DE DE10314610A patent/DE10314610A1/de not_active Withdrawn
-
2004
- 2004-02-24 JO JO200418A patent/JO2493B1/en active
- 2004-03-16 EP EP04720854A patent/EP1613589B1/de not_active Expired - Lifetime
- 2004-03-16 DE DE502004006195T patent/DE502004006195D1/de not_active Expired - Lifetime
- 2004-03-16 PL PL04720854T patent/PL1613589T3/pl unknown
- 2004-03-16 DE DE502004009059T patent/DE502004009059D1/de not_active Expired - Lifetime
- 2004-03-16 CN CNA2007101491852A patent/CN101139306A/zh active Pending
- 2004-03-16 BR BRPI0408920-0A patent/BRPI0408920A/pt not_active IP Right Cessation
- 2004-03-16 WO PCT/EP2004/002690 patent/WO2004087655A1/de active IP Right Grant
- 2004-03-16 KR KR1020057018705A patent/KR20050119180A/ko not_active Application Discontinuation
- 2004-03-16 CN CNB2004800084976A patent/CN100361970C/zh not_active Expired - Fee Related
- 2004-03-16 PT PT04720854T patent/PT1613589E/pt unknown
- 2004-03-16 EP EP07016889A patent/EP1862455B1/de not_active Expired - Lifetime
- 2004-03-16 DK DK04720854T patent/DK1613589T3/da active
- 2004-03-16 ME MEP-414/08A patent/MEP41408A/xx unknown
- 2004-03-16 PL PL07016889T patent/PL1862455T3/pl unknown
- 2004-03-16 SI SI200431100T patent/SI1862455T1/sl unknown
- 2004-03-16 RS YUP-2005/0719A patent/RS51146B/sr unknown
- 2004-03-16 UA UAA200510204A patent/UA80754C2/uk unknown
- 2004-03-16 SI SI200430681T patent/SI1613589T1/sl unknown
- 2004-03-16 AT AT04720854T patent/ATE386020T1/de not_active IP Right Cessation
- 2004-03-16 ES ES07016889T patent/ES2322876T3/es not_active Expired - Lifetime
- 2004-03-16 ES ES04720854T patent/ES2298731T3/es not_active Expired - Lifetime
- 2004-03-16 RU RU2005133631/04A patent/RU2334737C2/ru not_active IP Right Cessation
- 2004-03-16 MX MXPA05010128A patent/MXPA05010128A/es active IP Right Grant
- 2004-03-16 DK DK07016889T patent/DK1862455T3/da active
- 2004-03-16 AU AU2004226287A patent/AU2004226287B2/en not_active Ceased
- 2004-03-16 AT AT07016889T patent/ATE423766T1/de not_active IP Right Cessation
- 2004-03-16 CA CA002520689A patent/CA2520689A1/en not_active Abandoned
- 2004-03-16 JP JP2006504695A patent/JP2006522040A/ja active Pending
- 2004-03-16 PT PT07016889T patent/PT1862455E/pt unknown
- 2004-03-16 NZ NZ542751A patent/NZ542751A/en unknown
- 2004-03-29 HN HN2004000109A patent/HN2004000109A/es unknown
- 2004-03-29 PE PE2004000330A patent/PE20050011A1/es not_active Application Discontinuation
- 2004-03-30 TW TW093108581A patent/TW200504009A/zh unknown
- 2004-03-30 AR ARP040101052A patent/AR043783A1/es unknown
- 2004-03-30 PA PA20048599401A patent/PA8599401A1/es unknown
- 2004-03-31 US US10/813,954 patent/US7205290B2/en not_active Expired - Fee Related
- 2004-03-31 GT GT200400058A patent/GT200400058A/es unknown
- 2004-03-31 MY MYPI20041165A patent/MY136269A/en unknown
- 2004-03-31 UY UY28253A patent/UY28253A1/es unknown
- 2004-03-31 SV SV2004001756A patent/SV2004001756A/es not_active Application Discontinuation
- 2004-04-01 CL CL200400708A patent/CL43489B/es active
- 2004-06-09 SA SA04250154A patent/SA04250154B1/ar unknown
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2005
- 2005-08-22 ZA ZA200506708A patent/ZA200506708B/en unknown
- 2005-09-19 CR CR7995A patent/CR7995A/es unknown
- 2005-09-22 NI NI200500164A patent/NI200500164A/es unknown
- 2005-09-30 EC EC2005006071A patent/ECSP056071A/es unknown
- 2005-09-30 TN TNP2005000244A patent/TNSN05244A1/en unknown
- 2005-09-30 MA MA28529A patent/MA27753A1/fr unknown
- 2005-09-30 HR HR20050870A patent/HRP20050870A2/xx not_active Application Discontinuation
- 2005-10-27 NO NO20055001A patent/NO20055001L/no not_active Application Discontinuation
-
2006
- 2006-07-13 HK HK06107823A patent/HK1087697A1/xx not_active IP Right Cessation
-
2007
- 2007-03-26 US US11/690,993 patent/US7772429B2/en not_active Expired - Fee Related
-
2008
- 2008-04-17 CY CY20081100429T patent/CY1107398T1/el unknown
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2009
- 2009-05-11 CY CY20091100503T patent/CY1109055T1/el unknown
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