DK1862455T3 - Diphenylazetidinon - Google Patents

Diphenylazetidinon

Info

Publication number
DK1862455T3
DK1862455T3 DK07016889T DK07016889T DK1862455T3 DK 1862455 T3 DK1862455 T3 DK 1862455T3 DK 07016889 T DK07016889 T DK 07016889T DK 07016889 T DK07016889 T DK 07016889T DK 1862455 T3 DK1862455 T3 DK 1862455T3
Authority
DK
Denmark
Prior art keywords
diphenylazetidinone
Prior art date
Application number
DK07016889T
Other languages
English (en)
Inventor
Gerhard Dr Jaehne
Wendelin Dr Frick
Andreas Dr Lindenschmidt
Stefanie Dr Flohr
Hubert Dr Heuer
Hans-Ludwig Schaefer
Werner Prof Dr Kramer
Eric Dr Galia
Heiner Dr Glombik
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1862455T3 publication Critical patent/DK1862455T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK07016889T 2003-04-01 2004-03-16 Diphenylazetidinon DK1862455T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
PCT/EP2004/002690 WO2004087655A1 (de) 2003-04-01 2004-03-16 Neues diphenylazetidinon mit verbesserten physiologischen eigenschaften, verfahren zu dessen herstellung, diese verbindungen enthaltende arzneimittel und dessen verwendung

Publications (1)

Publication Number Publication Date
DK1862455T3 true DK1862455T3 (da) 2009-06-02

Family

ID=33103147

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04720854T DK1613589T3 (da) 2003-04-01 2004-03-16 Diphenylazetidinon
DK07016889T DK1862455T3 (da) 2003-04-01 2004-03-16 Diphenylazetidinon

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK04720854T DK1613589T3 (da) 2003-04-01 2004-03-16 Diphenylazetidinon

Country Status (44)

Country Link
US (2) US7205290B2 (da)
EP (2) EP1862455B1 (da)
JP (1) JP2006522040A (da)
KR (1) KR20050119180A (da)
CN (2) CN101139306A (da)
AR (1) AR043783A1 (da)
AT (2) ATE386020T1 (da)
AU (1) AU2004226287B2 (da)
BR (1) BRPI0408920A (da)
CA (1) CA2520689A1 (da)
CL (1) CL43489B (da)
CR (1) CR7995A (da)
CY (2) CY1107398T1 (da)
DE (3) DE10314610A1 (da)
DK (2) DK1613589T3 (da)
EC (1) ECSP056071A (da)
ES (2) ES2298731T3 (da)
GT (1) GT200400058A (da)
HK (1) HK1087697A1 (da)
HN (1) HN2004000109A (da)
HR (1) HRP20050870A2 (da)
JO (1) JO2493B1 (da)
MA (1) MA27753A1 (da)
ME (1) MEP41408A (da)
MX (1) MXPA05010128A (da)
MY (1) MY136269A (da)
NI (1) NI200500164A (da)
NO (1) NO20055001L (da)
NZ (1) NZ542751A (da)
PA (1) PA8599401A1 (da)
PE (1) PE20050011A1 (da)
PL (2) PL1862455T3 (da)
PT (2) PT1862455E (da)
RS (1) RS51146B (da)
RU (1) RU2334737C2 (da)
SA (1) SA04250154B1 (da)
SI (2) SI1862455T1 (da)
SV (1) SV2004001756A (da)
TN (1) TNSN05244A1 (da)
TW (1) TW200504009A (da)
UA (1) UA80754C2 (da)
UY (1) UY28253A1 (da)
WO (1) WO2004087655A1 (da)
ZA (1) ZA200506708B (da)

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CN101243072A (zh) 2005-06-20 2008-08-13 先灵公司 用作组胺h3拮抗剂的哌啶衍生物
US7067689B1 (en) 2005-07-08 2006-06-27 Microbia, Inc. Process for production of pentahydroxyhexylcarbamoyl alkanoic acids
WO2008017381A1 (de) 2006-08-08 2008-02-14 Sanofi-Aventis Arylaminoaryl-alkyl-substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
US20080319221A1 (en) * 2007-06-22 2008-12-25 Bernd Junker Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
US20080319218A1 (en) * 2007-06-22 2008-12-25 Andreas Haubrich Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
DE102007029612A1 (de) * 2007-06-27 2009-01-08 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de) * 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
CN101939009B (zh) * 2008-02-05 2013-07-17 哈博生物科学公司 药学固体形式
DE102008059772A1 (de) 2008-12-01 2010-06-02 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung eines Diphenylazetidinons
WO2009112203A1 (de) * 2008-03-14 2009-09-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur herstellung eines diphenylazetidinons
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
WO2012120057A1 (de) 2011-03-08 2012-09-13 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US10426480B2 (en) * 2015-04-29 2019-10-01 Covidien Lp Cutting ring assembly with rigid cutting member

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Also Published As

Publication number Publication date
SI1613589T1 (sl) 2008-06-30
HK1087697A1 (en) 2006-10-20
MXPA05010128A (es) 2005-11-16
EP1613589B1 (de) 2008-02-13
SV2004001756A (es) 2004-11-18
ATE423766T1 (de) 2009-03-15
TNSN05244A1 (en) 2007-06-11
RU2334737C2 (ru) 2008-09-27
NI200500164A (es) 2006-01-11
MA27753A1 (fr) 2006-02-01
CY1109055T1 (el) 2014-07-02
DE502004006195D1 (de) 2008-03-27
MY136269A (en) 2008-09-30
MEP41408A (en) 2011-02-10
PT1862455E (pt) 2009-04-23
EP1862455B1 (de) 2009-02-25
AR043783A1 (es) 2005-08-10
CY1107398T1 (el) 2012-12-19
KR20050119180A (ko) 2005-12-20
RS51146B (sr) 2010-10-31
ATE386020T1 (de) 2008-03-15
ES2298731T3 (es) 2008-05-16
SA04250154B1 (ar) 2007-10-29
CN1768034A (zh) 2006-05-03
CL43489B (es) 2005-01-21
SI1862455T1 (sl) 2009-06-30
CN100361970C (zh) 2008-01-16
EP1862455A3 (de) 2007-12-12
RU2005133631A (ru) 2006-03-10
JO2493B1 (en) 2009-10-05
PL1862455T3 (pl) 2009-07-31
TW200504009A (en) 2005-02-01
UA80754C2 (en) 2007-10-25
PT1613589E (pt) 2008-03-27
DE502004009059D1 (de) 2009-04-09
ES2322876T3 (es) 2009-06-30
PL1613589T3 (pl) 2008-07-31
ECSP056071A (es) 2006-01-27
AU2004226287A1 (en) 2004-10-14
DK1613589T3 (da) 2008-06-09
NZ542751A (en) 2007-05-31
WO2004087655A1 (de) 2004-10-14
UY28253A1 (es) 2004-11-08
PE20050011A1 (es) 2005-02-28
HN2004000109A (es) 2008-02-21
JP2006522040A (ja) 2006-09-28
CN101139306A (zh) 2008-03-12
GT200400058A (es) 2004-11-10
PA8599401A1 (es) 2004-10-08
US20070197498A1 (en) 2007-08-23
HRP20050870A2 (en) 2006-10-31
ZA200506708B (en) 2007-01-31
RS20050719A (en) 2008-04-04
NO20055001L (no) 2005-10-27
BRPI0408920A (pt) 2006-03-28
EP1613589A1 (de) 2006-01-11
EP1862455A2 (de) 2007-12-05
US7205290B2 (en) 2007-04-17
US7772429B2 (en) 2010-08-10
US20050020563A1 (en) 2005-01-27
CA2520689A1 (en) 2004-10-14
AU2004226287B2 (en) 2010-03-18
CR7995A (es) 2006-09-22
DE10314610A1 (de) 2004-11-04

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