PA8599401A1 - Nueva difenilazetidinona con propiedades fisiologicas mejoradas, procedimiento para su preparacion, medicamentos que comprenden este compuesto y su uso - Google Patents
Nueva difenilazetidinona con propiedades fisiologicas mejoradas, procedimiento para su preparacion, medicamentos que comprenden este compuesto y su usoInfo
- Publication number
- PA8599401A1 PA8599401A1 PA20048599401A PA8599401A PA8599401A1 PA 8599401 A1 PA8599401 A1 PA 8599401A1 PA 20048599401 A PA20048599401 A PA 20048599401A PA 8599401 A PA8599401 A PA 8599401A PA 8599401 A1 PA8599401 A1 PA 8599401A1
- Authority
- PA
- Panama
- Prior art keywords
- difenylazethydinone
- drugs
- understand
- composite
- procedure
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Abstract
LA INVENCION SE REFIERE AL COMPUESTO DE LA FORMULA I Y A SUS SALES FISIOLOGICAMENTE ACEPTABLES. EL COMPUESTO ES ADECUADO, POR EJEMPLO, COMO HIPOLIPIDEMIANTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10314610A DE10314610A1 (de) | 2003-04-01 | 2003-04-01 | Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8599401A1 true PA8599401A1 (es) | 2004-10-08 |
Family
ID=33103147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20048599401A PA8599401A1 (es) | 2003-04-01 | 2004-03-30 | Nueva difenilazetidinona con propiedades fisiologicas mejoradas, procedimiento para su preparacion, medicamentos que comprenden este compuesto y su uso |
Country Status (44)
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
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ES2277890T3 (es) * | 2000-12-21 | 2007-08-01 | Sanofi-Aventis Deutschland Gmbh | Nuevas difenilazetidinonas, procedimiento para su preparacion, medicamentos que contienen estos compuestos y su uso para el tratamiento de trastornos del metabolismo de lipidos. |
WO2007001975A1 (en) | 2005-06-20 | 2007-01-04 | Schering Corporation | Piperidine derivatives useful as histamine h3 antagonists |
US7067689B1 (en) | 2005-07-08 | 2006-06-27 | Microbia, Inc. | Process for production of pentahydroxyhexylcarbamoyl alkanoic acids |
MX2009001043A (es) | 2006-08-08 | 2009-02-06 | Sanofi Aventis | Imidazolidina-2,4-dionas sustituidas con arilaminoarilalquilo, procedimiento para preparalas, medicamentos que comprenden estos compuestos y su uso. |
US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
DE102007029612A1 (de) * | 2007-06-27 | 2009-01-08 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester |
US20080319218A1 (en) * | 2007-06-22 | 2008-12-25 | Andreas Haubrich | Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE102007063671A1 (de) * | 2007-11-13 | 2009-06-25 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
EP2249838A4 (en) * | 2008-02-05 | 2012-05-02 | Harbor Biosciences Inc | PHARMACEUTICAL FORMS IN SOLID STATE |
DE102008059772A1 (de) | 2008-12-01 | 2010-06-02 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung eines Diphenylazetidinons |
WO2009112203A1 (de) * | 2008-03-14 | 2009-09-17 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur herstellung eines diphenylazetidinons |
DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2683702B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120051A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8846666B2 (en) | 2011-03-08 | 2014-09-30 | Sanofi | Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120057A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
US10426480B2 (en) * | 2015-04-29 | 2019-10-01 | Covidien Lp | Cutting ring assembly with rigid cutting member |
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FR2663336B1 (fr) | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5756740A (en) * | 1992-04-08 | 1998-05-26 | Eastman Kodak Company | Process for the preparation of binary sensitizing dyes |
FR2713225B1 (fr) | 1993-12-02 | 1996-03-01 | Sanofi Sa | N-pipéridino-3-pyrazolecarboxamide substitué. |
PL327938A1 (en) | 1996-01-17 | 1999-01-04 | Novo Nordisk As | Derivatives of 1,2,4-thiadiazine and 1,4-thiazine, their production and application |
DK0944648T3 (da) | 1996-08-30 | 2007-07-02 | Novo Nordisk As | GLP-1 derivater |
US5756470A (en) * | 1996-10-29 | 1998-05-26 | Schering Corporation | Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents |
DE19726167B4 (de) * | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
HUP0003999A3 (en) | 1997-07-16 | 2003-03-28 | Novo Nordisk As | Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them |
CO4970713A1 (es) | 1997-09-19 | 2000-11-07 | Sanofi Synthelabo | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen |
CA2323456A1 (en) | 1998-03-12 | 1999-09-16 | Teijin Limited | Benzofurylpyrone derivatives |
US6221897B1 (en) * | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
DE19845405C2 (de) * | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
KR20050037004A (ko) | 1998-12-07 | 2005-04-20 | 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. | Glp-1의 유사체 |
GB9900416D0 (en) | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
HUP0201291A3 (en) | 1999-04-28 | 2002-11-28 | Sanofi Aventis Deutschland | Di-aryl acid derivatives as ppar receptor ligands and pharmaceutical compositions containing them |
SK15522001A3 (sk) | 1999-04-28 | 2002-06-04 | Aventis Pharma Deutschland Gmbh | Deriváty kyselín s tromi arylovými zvyškami ako ligandy receptorov PPAR a farmaceutické kompozície, ktoré ich obsahujú |
GB9911863D0 (en) | 1999-05-21 | 1999-07-21 | Knoll Ag | Therapeutic agents |
WO2000078312A1 (en) | 1999-06-18 | 2000-12-28 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
ATE245636T1 (de) | 1999-07-29 | 2003-08-15 | Lilly Co Eli | Benzofurylpiperazine: 5-ht2c serotoninrezeptor agonisten |
IL148148A0 (en) * | 1999-09-01 | 2002-09-12 | Aventis Pharma Gmbh | Sulfonyl carboxamide derivatives, method for their production and their use as medicaments |
WO2001062266A2 (en) | 2000-02-25 | 2001-08-30 | Novo Nordisk A/S | Use of dpp-iv inhibitors for the treatment of diabetes |
AU2001252574B2 (en) | 2000-04-28 | 2005-03-17 | Asahi Kasei Pharma Corporation | Novel bicyclic compounds |
AU2001259592B2 (en) | 2000-05-11 | 2005-02-24 | Bristol-Myers Squibb Co. | Tetrahydroisoquinoline analogs useful as growth hormone secretagogues |
SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
HUP0004741A2 (hu) | 2000-11-28 | 2002-12-28 | Sanofi-Synthelabo | Kémiai eljárás tiazolszármazékok előállítására és új intermedier |
ES2277890T3 (es) * | 2000-12-21 | 2007-08-01 | Sanofi-Aventis Deutschland Gmbh | Nuevas difenilazetidinonas, procedimiento para su preparacion, medicamentos que contienen estos compuestos y su uso para el tratamiento de trastornos del metabolismo de lipidos. |
DE10139416A1 (de) | 2001-08-17 | 2003-03-06 | Aventis Pharma Gmbh | Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
ATE347890T1 (de) * | 2001-08-31 | 2007-01-15 | Sanofi Aventis Deutschland | Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar- aktivatoren |
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US7176194B2 (en) * | 2002-06-19 | 2007-02-13 | Sanofi-Aventis Deutschland Gmbh | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use |
GB0215579D0 (en) * | 2002-07-05 | 2002-08-14 | Astrazeneca Ab | Chemical compounds |
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2003
- 2003-04-01 DE DE10314610A patent/DE10314610A1/de not_active Withdrawn
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2004
- 2004-02-24 JO JO200418A patent/JO2493B1/en active
- 2004-03-16 RU RU2005133631/04A patent/RU2334737C2/ru not_active IP Right Cessation
- 2004-03-16 SI SI200431100T patent/SI1862455T1/sl unknown
- 2004-03-16 DE DE502004006195T patent/DE502004006195D1/de not_active Expired - Lifetime
- 2004-03-16 AT AT07016889T patent/ATE423766T1/de not_active IP Right Cessation
- 2004-03-16 CN CNA2007101491852A patent/CN101139306A/zh active Pending
- 2004-03-16 BR BRPI0408920-0A patent/BRPI0408920A/pt not_active IP Right Cessation
- 2004-03-16 NZ NZ542751A patent/NZ542751A/en unknown
- 2004-03-16 ES ES04720854T patent/ES2298731T3/es not_active Expired - Lifetime
- 2004-03-16 DK DK04720854T patent/DK1613589T3/da active
- 2004-03-16 AU AU2004226287A patent/AU2004226287B2/en not_active Ceased
- 2004-03-16 ME MEP-414/08A patent/MEP41408A/xx unknown
- 2004-03-16 RS YUP-2005/0719A patent/RS51146B/sr unknown
- 2004-03-16 EP EP07016889A patent/EP1862455B1/de not_active Expired - Lifetime
- 2004-03-16 UA UAA200510204A patent/UA80754C2/uk unknown
- 2004-03-16 PL PL07016889T patent/PL1862455T3/pl unknown
- 2004-03-16 PT PT04720854T patent/PT1613589E/pt unknown
- 2004-03-16 KR KR1020057018705A patent/KR20050119180A/ko not_active Application Discontinuation
- 2004-03-16 DE DE502004009059T patent/DE502004009059D1/de not_active Expired - Lifetime
- 2004-03-16 CN CNB2004800084976A patent/CN100361970C/zh not_active Expired - Fee Related
- 2004-03-16 CA CA002520689A patent/CA2520689A1/en not_active Abandoned
- 2004-03-16 DK DK07016889T patent/DK1862455T3/da active
- 2004-03-16 AT AT04720854T patent/ATE386020T1/de not_active IP Right Cessation
- 2004-03-16 WO PCT/EP2004/002690 patent/WO2004087655A1/de active IP Right Grant
- 2004-03-16 EP EP04720854A patent/EP1613589B1/de not_active Expired - Lifetime
- 2004-03-16 JP JP2006504695A patent/JP2006522040A/ja active Pending
- 2004-03-16 PT PT07016889T patent/PT1862455E/pt unknown
- 2004-03-16 PL PL04720854T patent/PL1613589T3/pl unknown
- 2004-03-16 SI SI200430681T patent/SI1613589T1/sl unknown
- 2004-03-16 MX MXPA05010128A patent/MXPA05010128A/es active IP Right Grant
- 2004-03-16 ES ES07016889T patent/ES2322876T3/es not_active Expired - Lifetime
- 2004-03-29 HN HN2004000109A patent/HN2004000109A/es unknown
- 2004-03-29 PE PE2004000330A patent/PE20050011A1/es not_active Application Discontinuation
- 2004-03-30 AR ARP040101052A patent/AR043783A1/es unknown
- 2004-03-30 TW TW093108581A patent/TW200504009A/zh unknown
- 2004-03-30 PA PA20048599401A patent/PA8599401A1/es unknown
- 2004-03-31 GT GT200400058A patent/GT200400058A/es unknown
- 2004-03-31 UY UY28253A patent/UY28253A1/es unknown
- 2004-03-31 SV SV2004001756A patent/SV2004001756A/es not_active Application Discontinuation
- 2004-03-31 MY MYPI20041165A patent/MY136269A/en unknown
- 2004-03-31 US US10/813,954 patent/US7205290B2/en not_active Expired - Fee Related
- 2004-04-01 CL CL200400708A patent/CL43489B/es active
- 2004-06-09 SA SA04250154A patent/SA04250154B1/ar unknown
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2005
- 2005-08-22 ZA ZA200506708A patent/ZA200506708B/en unknown
- 2005-09-19 CR CR7995A patent/CR7995A/es unknown
- 2005-09-22 NI NI200500164A patent/NI200500164A/es unknown
- 2005-09-30 EC EC2005006071A patent/ECSP056071A/es unknown
- 2005-09-30 TN TNP2005000244A patent/TNSN05244A1/en unknown
- 2005-09-30 HR HR20050870A patent/HRP20050870A2/xx not_active Application Discontinuation
- 2005-09-30 MA MA28529A patent/MA27753A1/fr unknown
- 2005-10-27 NO NO20055001A patent/NO20055001L/no not_active Application Discontinuation
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2006
- 2006-07-13 HK HK06107823A patent/HK1087697A1/xx not_active IP Right Cessation
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2007
- 2007-03-26 US US11/690,993 patent/US7772429B2/en not_active Expired - Fee Related
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2008
- 2008-04-17 CY CY20081100429T patent/CY1107398T1/el unknown
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2009
- 2009-05-11 CY CY20091100503T patent/CY1109055T1/el unknown
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