MEP41408A - Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter - Google Patents

Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter

Info

Publication number
MEP41408A
MEP41408A MEP-414/08A MEP41408A MEP41408A ME P41408 A MEP41408 A ME P41408A ME P41408 A MEP41408 A ME P41408A ME P41408 A MEP41408 A ME P41408A
Authority
ME
Montenegro
Prior art keywords
compound
production method
physiological characteristics
corresponding production
medicaments containing
Prior art date
Application number
MEP-414/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Gerhard Jaehne
Wendelin Frick
Andreas Lindenschmidt
Stefanie Flohr
Hubert Heuer
Hans-Ludwig Schaefer
Werner Kramer
Eric Galia
Heiner Glombik
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MEP41408A publication Critical patent/MEP41408A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
MEP-414/08A 2003-04-01 2004-03-16 Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter MEP41408A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
PCT/EP2004/002690 WO2004087655A1 (de) 2003-04-01 2004-03-16 Neues diphenylazetidinon mit verbesserten physiologischen eigenschaften, verfahren zu dessen herstellung, diese verbindungen enthaltende arzneimittel und dessen verwendung

Publications (1)

Publication Number Publication Date
MEP41408A true MEP41408A (en) 2011-02-10

Family

ID=33103147

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-414/08A MEP41408A (en) 2003-04-01 2004-03-16 Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter

Country Status (44)

Country Link
US (2) US7205290B2 (xx)
EP (2) EP1862455B1 (xx)
JP (1) JP2006522040A (xx)
KR (1) KR20050119180A (xx)
CN (2) CN101139306A (xx)
AR (1) AR043783A1 (xx)
AT (2) ATE423766T1 (xx)
AU (1) AU2004226287B2 (xx)
BR (1) BRPI0408920A (xx)
CA (1) CA2520689A1 (xx)
CL (1) CL43489B (xx)
CR (1) CR7995A (xx)
CY (2) CY1107398T1 (xx)
DE (3) DE10314610A1 (xx)
DK (2) DK1613589T3 (xx)
EC (1) ECSP056071A (xx)
ES (2) ES2298731T3 (xx)
GT (1) GT200400058A (xx)
HK (1) HK1087697A1 (xx)
HN (1) HN2004000109A (xx)
HR (1) HRP20050870A2 (xx)
JO (1) JO2493B1 (xx)
MA (1) MA27753A1 (xx)
ME (1) MEP41408A (xx)
MX (1) MXPA05010128A (xx)
MY (1) MY136269A (xx)
NI (1) NI200500164A (xx)
NO (1) NO20055001L (xx)
NZ (1) NZ542751A (xx)
PA (1) PA8599401A1 (xx)
PE (1) PE20050011A1 (xx)
PL (2) PL1862455T3 (xx)
PT (2) PT1613589E (xx)
RS (1) RS51146B (xx)
RU (1) RU2334737C2 (xx)
SA (1) SA04250154B1 (xx)
SI (2) SI1862455T1 (xx)
SV (1) SV2004001756A (xx)
TN (1) TNSN05244A1 (xx)
TW (1) TW200504009A (xx)
UA (1) UA80754C2 (xx)
UY (1) UY28253A1 (xx)
WO (1) WO2004087655A1 (xx)
ZA (1) ZA200506708B (xx)

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US20080319221A1 (en) * 2007-06-22 2008-12-25 Bernd Junker Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
DE102007029612A1 (de) * 2007-06-27 2009-01-08 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester
US20080319218A1 (en) * 2007-06-22 2008-12-25 Andreas Haubrich Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007063671A1 (de) * 2007-11-13 2009-06-25 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP2249838A4 (en) * 2008-02-05 2012-05-02 Harbor Biosciences Inc PHARMACEUTICAL FORMS IN SOLID STATE
DE102008059772A1 (de) 2008-12-01 2010-06-02 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung eines Diphenylazetidinons
WO2009112203A1 (de) * 2008-03-14 2009-09-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur herstellung eines diphenylazetidinons
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120057A1 (de) 2011-03-08 2012-09-13 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US10426480B2 (en) * 2015-04-29 2019-10-01 Covidien Lp Cutting ring assembly with rigid cutting member

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Also Published As

Publication number Publication date
NI200500164A (es) 2006-01-11
HK1087697A1 (en) 2006-10-20
EP1862455B1 (de) 2009-02-25
EP1613589B1 (de) 2008-02-13
EP1862455A2 (de) 2007-12-05
SI1862455T1 (sl) 2009-06-30
JO2493B1 (en) 2009-10-05
DE502004006195D1 (de) 2008-03-27
US7205290B2 (en) 2007-04-17
CR7995A (es) 2006-09-22
HRP20050870A2 (en) 2006-10-31
TNSN05244A1 (en) 2007-06-11
SV2004001756A (es) 2004-11-18
CY1107398T1 (el) 2012-12-19
CL43489B (es) 2005-01-21
UA80754C2 (en) 2007-10-25
RS20050719A (xx) 2008-04-04
AU2004226287A1 (en) 2004-10-14
DE10314610A1 (de) 2004-11-04
MY136269A (en) 2008-09-30
ES2322876T3 (es) 2009-06-30
WO2004087655A1 (de) 2004-10-14
PT1862455E (pt) 2009-04-23
US20070197498A1 (en) 2007-08-23
HN2004000109A (es) 2008-02-21
GT200400058A (es) 2004-11-10
AU2004226287B2 (en) 2010-03-18
BRPI0408920A (pt) 2006-03-28
MA27753A1 (fr) 2006-02-01
RS51146B (sr) 2010-10-31
CN1768034A (zh) 2006-05-03
US20050020563A1 (en) 2005-01-27
PA8599401A1 (es) 2004-10-08
ECSP056071A (es) 2006-01-27
DE502004009059D1 (de) 2009-04-09
DK1862455T3 (da) 2009-06-02
CY1109055T1 (el) 2014-07-02
PL1613589T3 (pl) 2008-07-31
AR043783A1 (es) 2005-08-10
NO20055001L (no) 2005-10-27
JP2006522040A (ja) 2006-09-28
PL1862455T3 (pl) 2009-07-31
CN100361970C (zh) 2008-01-16
SA04250154B1 (ar) 2007-10-29
DK1613589T3 (da) 2008-06-09
ATE386020T1 (de) 2008-03-15
US7772429B2 (en) 2010-08-10
KR20050119180A (ko) 2005-12-20
EP1613589A1 (de) 2006-01-11
CN101139306A (zh) 2008-03-12
NZ542751A (en) 2007-05-31
PE20050011A1 (es) 2005-02-28
MXPA05010128A (es) 2005-11-16
ES2298731T3 (es) 2008-05-16
SI1613589T1 (sl) 2008-06-30
ATE423766T1 (de) 2009-03-15
ZA200506708B (en) 2007-01-31
UY28253A1 (es) 2004-11-08
RU2334737C2 (ru) 2008-09-27
TW200504009A (en) 2005-02-01
EP1862455A3 (de) 2007-12-12
RU2005133631A (ru) 2006-03-10
PT1613589E (pt) 2008-03-27
CA2520689A1 (en) 2004-10-14

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