HRP20040433A2 - Macrolides - Google Patents

Macrolides

Info

Publication number
HRP20040433A2
HRP20040433A2 HR20040433A HRP20040433A HRP20040433A2 HR P20040433 A2 HRP20040433 A2 HR P20040433A2 HR 20040433 A HR20040433 A HR 20040433A HR P20040433 A HRP20040433 A HR P20040433A HR P20040433 A2 HRP20040433 A2 HR P20040433A2
Authority
HR
Croatia
Prior art keywords
amino
dihydro
oxo
ethyl
cyclopropyl
Prior art date
Application number
HR20040433A
Other languages
English (en)
Croatian (hr)
Inventor
Alihod�i� Sulejman
Andreotti Daniele
Berdik Andrea
Bientinesi Ilaria
Biondi Stefano
Ciraco Manuela
Damiani Federica
Djerek Marko
Dumi� Miljenko
Erakovic Vesna
Hutinec Antun
Lazarevski Gorjana
Lociuro Sergio
Mar�i� Nata�a
Maru�i�-I�tuk Zorica
Mutak Stjepan
Paio Alfredo
Pavlovi� Dra�en
Quaglia Anna
Schoenfeld Wolfgang
Stimac Vlado
Tibasco Jessica
Original Assignee
Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited filed Critical Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Publication of HRP20040433A2 publication Critical patent/HRP20040433A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
HR20040433A 2001-11-14 2002-11-13 Macrolides HRP20040433A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides
PCT/GB2002/005101 WO2003042228A1 (en) 2001-11-14 2002-11-13 Macrolides

Publications (1)

Publication Number Publication Date
HRP20040433A2 true HRP20040433A2 (en) 2005-04-30

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040433A HRP20040433A2 (en) 2001-11-14 2002-11-13 Macrolides

Country Status (20)

Country Link
US (1) US7202221B2 (OSRAM)
EP (1) EP1453846B1 (OSRAM)
JP (1) JP2005515978A (OSRAM)
CN (1) CN1307194C (OSRAM)
AR (1) AR037371A1 (OSRAM)
AT (1) ATE362479T1 (OSRAM)
BR (1) BR0214132A (OSRAM)
CA (1) CA2466975A1 (OSRAM)
DE (1) DE60220180T2 (OSRAM)
EA (1) EA007433B1 (OSRAM)
ES (1) ES2287332T3 (OSRAM)
GB (1) GB0127349D0 (OSRAM)
HR (1) HRP20040433A2 (OSRAM)
HU (1) HUP0402225A3 (OSRAM)
IL (1) IL161710A0 (OSRAM)
PL (1) PL371472A1 (OSRAM)
RS (1) RS41904A (OSRAM)
UA (1) UA77210C2 (OSRAM)
WO (1) WO2003042228A1 (OSRAM)
ZA (1) ZA200403684B (OSRAM)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
WO2005070918A1 (en) 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
CA2484308A1 (en) * 2002-05-14 2003-11-27 The Regents Of The University Of California Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
ES2278319T3 (es) * 2003-05-13 2007-08-01 Glaxo Group Limited Nuevos compuestos con 14 y 15 miembros en el anillo.
GB0310986D0 (en) 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2005030227A1 (en) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
US7265094B2 (en) 2004-01-09 2007-09-04 Enanta Pharmaceuticals, Inc. 9N-substituted 6-11 bicyclic erythromycin derivatives
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US20080249033A1 (en) * 2004-05-06 2008-10-09 Sulejman Alihodzic Carbamate Linked Macrolides Useful For The Treatment Of Microbial Infections
DE602005015963D1 (de) * 2004-05-06 2009-09-24 Glaxosmithkline Zagreb Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424959D0 (en) 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
PT2049556E (pt) 2006-08-09 2013-08-22 Basilea Pharmaceutica Ag Novos macrólidos úteis contra doenças inflamatórias e alérgicas
EP2056844A4 (en) 2006-08-24 2010-11-24 Wockhardt Research Center NEW MACROLIDS AND KETOLIDS WITH ANTIMICROBIAL EFFECT
CN101939327B (zh) 2008-02-08 2015-03-11 巴斯利尔药物股份公司 新的大环内酯类及其用途
RU2011153353A (ru) 2009-05-27 2013-07-10 Вокхардт Рисерч Сентер Кетолидные соединения, обладающие противомикробной активностью
EP3216798A3 (en) 2010-12-09 2017-10-25 Wockhardt Limited Ketolide compounds
WO2012105562A1 (ja) * 2011-01-31 2012-08-09 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 新規マクロライド誘導体
US9206214B2 (en) 2011-03-01 2015-12-08 Wockhardt Ltd. Process for preparation of ketolide intermediates
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
EP0465581B1 (en) 1989-03-28 1995-10-04 Abbott Laboratories Erythromycin derivatives
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
DK1007530T3 (da) 1996-05-07 2006-04-03 Abbott Lab 6-O-substituerede erythromycinforbindelser samt fremgangsmåde til fremstilling heraf
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6262030B1 (en) 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
ATE315042T1 (de) 1999-08-24 2006-02-15 Abbott Lab 9a-azalide mit antibakterieller wirkung
ATE312839T1 (de) 2000-02-24 2005-12-15 Abbott Lab Anti-infektionsmittel, die gegen gegenüber mehreren arzneimitteln resistente bakterienstämme nützlich sind
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
DE60220180D1 (de) 2007-06-28
EP1453846B1 (en) 2007-05-16
EA007433B1 (ru) 2006-10-27
HUP0402225A2 (hu) 2005-02-28
ATE362479T1 (de) 2007-06-15
RS41904A (sr) 2006-10-27
UA77210C2 (en) 2006-11-15
CA2466975A1 (en) 2003-05-22
ZA200403684B (en) 2005-09-13
PL371472A1 (en) 2005-06-13
BR0214132A (pt) 2004-09-14
AR037371A1 (es) 2004-11-03
JP2005515978A (ja) 2005-06-02
CN1307194C (zh) 2007-03-28
DE60220180T2 (de) 2008-01-17
EA200400536A1 (ru) 2004-12-30
IL161710A0 (en) 2004-09-27
HUP0402225A3 (en) 2006-01-30
EP1453846A1 (en) 2004-09-08
ES2287332T3 (es) 2007-12-16
GB0127349D0 (en) 2002-01-02
WO2003042228A1 (en) 2003-05-22
US7202221B2 (en) 2007-04-10
CN1612888A (zh) 2005-05-04
US20050080025A1 (en) 2005-04-14

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Legal Events

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Payment date: 20081111

Year of fee payment: 7

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