HRP20031021B1 - Stereoselektivni postupak za izradu nukleozidnih analoga - Google Patents

Stereoselektivni postupak za izradu nukleozidnih analoga

Info

Publication number
HRP20031021B1
HRP20031021B1 HR20031021A HRP20031021A HRP20031021B1 HR P20031021 B1 HRP20031021 B1 HR P20031021B1 HR 20031021 A HR20031021 A HR 20031021A HR P20031021 A HRP20031021 A HR P20031021A HR P20031021 B1 HRP20031021 B1 HR P20031021B1
Authority
HR
Croatia
Prior art keywords
formula
bromine
iodine
chlorine
alkoxy
Prior art date
Application number
HR20031021A
Other languages
English (en)
Croatian (hr)
Inventor
Yu Qing
Original Assignee
Shire Biochem Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Biochem Inc. filed Critical Shire Biochem Inc.
Publication of HRP20031021A2 publication Critical patent/HRP20031021A2/xx
Publication of HRP20031021B1 publication Critical patent/HRP20031021B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
HR20031021A 2001-06-15 2002-06-14 Stereoselektivni postupak za izradu nukleozidnih analoga HRP20031021B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29807901P 2001-06-15 2001-06-15
PCT/CA2002/000899 WO2002102796A1 (en) 2001-06-15 2002-06-14 Stereoselective method for the preparation of nucleoside analogues

Publications (2)

Publication Number Publication Date
HRP20031021A2 HRP20031021A2 (en) 2004-06-30
HRP20031021B1 true HRP20031021B1 (hr) 2007-09-30

Family

ID=23148927

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20031021A HRP20031021B1 (hr) 2001-06-15 2002-06-14 Stereoselektivni postupak za izradu nukleozidnih analoga

Country Status (28)

Country Link
US (2) US7109334B2 (enExample)
EP (2) EP1632490B1 (enExample)
JP (1) JP4542776B2 (enExample)
KR (1) KR100832617B1 (enExample)
CN (1) CN1297553C (enExample)
AP (1) AP1559A (enExample)
AT (2) ATE313542T1 (enExample)
AU (2) AU2002344862C1 (enExample)
BR (2) BR0210444A (enExample)
CA (1) CA2449338C (enExample)
CO (1) CO5550497A2 (enExample)
CY (1) CY1107805T1 (enExample)
DE (2) DE60222031T2 (enExample)
DK (2) DK1632490T3 (enExample)
EA (1) EA006372B1 (enExample)
ES (2) ES2293445T3 (enExample)
HR (1) HRP20031021B1 (enExample)
IL (2) IL159139A0 (enExample)
MX (1) MXPA03011627A (enExample)
NO (1) NO326135B1 (enExample)
NZ (1) NZ529906A (enExample)
OA (1) OA12628A (enExample)
PL (2) PL215267B1 (enExample)
PT (1) PT1632490E (enExample)
RS (1) RS50868B (enExample)
SI (2) SI1406896T1 (enExample)
WO (1) WO2002102796A1 (enExample)
ZA (1) ZA200309307B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501514B1 (en) 2003-10-15 2009-03-10 Shire Biochem, Inc. Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides
JP4653966B2 (ja) * 2004-04-19 2011-03-16 ダイセル化学工業株式会社 2−ベンゾイルオキシアセトアルデヒド誘導体の製造法
WO2009039582A1 (en) * 2007-09-28 2009-04-02 Avexa Limited A process for chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes
US20130165350A1 (en) * 2011-12-22 2013-06-27 Affymetrix, Inc. Surface linkers for array synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR840001591A (ko) * 1981-09-29 1984-05-07 구라바야시 이꾸시로 당케탈류의 제조방법
US5587480A (en) * 1990-11-13 1996-12-24 Biochem Pharma, Inc. Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
ATE143016T1 (de) * 1990-11-13 1996-10-15 Iaf Biochem Int Substituierte 1,3-oxathiolane mit antiviralen eigenschaften
US5532349A (en) * 1993-07-20 1996-07-02 Mitsui Toatsu Chemicals, Inc. Process for producing 1-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-trifluoromethyluracil derivatives
ES2232169T3 (es) * 1998-08-12 2005-05-16 Gilead Sciences, Inc. Procedimiento de fabricacion de nucleosidos de 1,3-oxatiolano.

Also Published As

Publication number Publication date
NZ529906A (en) 2006-03-31
DE60208202T2 (de) 2006-08-17
DK1632490T3 (da) 2008-01-28
DE60222031D1 (de) 2007-10-04
SI1406896T1 (sl) 2006-04-30
AU2002344862B2 (en) 2008-05-01
EA200400042A1 (ru) 2004-06-24
KR100832617B1 (ko) 2008-05-27
HK1070652A1 (en) 2005-06-24
KR20040017233A (ko) 2004-02-26
CO5550497A2 (es) 2005-08-31
ATE370945T1 (de) 2007-09-15
JP2004535428A (ja) 2004-11-25
HRP20031021A2 (en) 2004-06-30
WO2002102796A8 (en) 2003-09-18
PL218777B1 (pl) 2015-01-30
WO2002102796A1 (en) 2002-12-27
PL366907A1 (en) 2005-02-07
US20060183899A1 (en) 2006-08-17
IL159139A (en) 2010-04-15
BR0210444A (pt) 2004-08-17
NO20035556D0 (no) 2003-12-12
BRPI0210444B1 (pt) 2017-06-20
NO326135B1 (no) 2008-10-06
JP4542776B2 (ja) 2010-09-15
CN1297553C (zh) 2007-01-31
AP1559A (en) 2006-01-24
YU97503A (sh) 2006-05-25
CA2449338A1 (en) 2002-12-27
SI1632490T1 (sl) 2008-02-29
PT1632490E (pt) 2007-11-07
DE60208202D1 (de) 2006-01-26
EP1632490B1 (en) 2007-08-22
EP1406896A1 (en) 2004-04-14
ZA200309307B (en) 2005-02-23
EP1406896B1 (en) 2005-12-21
PL215267B1 (pl) 2013-11-29
US7109334B2 (en) 2006-09-19
US7230100B2 (en) 2007-06-12
ES2293445T3 (es) 2008-03-16
ATE313542T1 (de) 2006-01-15
DK1406896T3 (da) 2006-05-08
US20030135048A1 (en) 2003-07-17
CA2449338C (en) 2012-02-07
OA12628A (en) 2006-06-13
CN1543463A (zh) 2004-11-03
EP1406896B8 (en) 2006-11-15
MXPA03011627A (es) 2005-03-07
IL159139A0 (en) 2004-06-01
AU2008203443B2 (en) 2011-06-16
EP1632490A1 (en) 2006-03-08
DE60222031T2 (de) 2008-05-21
EA006372B1 (ru) 2005-12-29
PL401835A1 (pl) 2013-02-18
CY1107805T1 (el) 2013-06-19
RS50868B (sr) 2010-08-31
AU2002344862C1 (en) 2009-02-19
AU2008203443A1 (en) 2008-08-21
ES2254695T3 (es) 2006-06-16

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
PNAN Change of the applicant name, address/residence

Owner name: SHIRE CANADA INC., CA

Owner name: SHIRE BIOCHEM INC., CA

ODRP Renewal fee for the maintenance of a patent

Payment date: 20170523

Year of fee payment: 16

PBON Lapse due to non-payment of renewal fee

Effective date: 20180614