ATE370945T1 - Stereoselektives verfahren zur herstellung von nukleosidderivaten - Google Patents

Stereoselektives verfahren zur herstellung von nukleosidderivaten

Info

Publication number
ATE370945T1
ATE370945T1 AT05017130T AT05017130T ATE370945T1 AT E370945 T1 ATE370945 T1 AT E370945T1 AT 05017130 T AT05017130 T AT 05017130T AT 05017130 T AT05017130 T AT 05017130T AT E370945 T1 ATE370945 T1 AT E370945T1
Authority
AT
Austria
Prior art keywords
nucleoside derivatives
stereoselective process
producing nucleoside
producing
stereoselective
Prior art date
Application number
AT05017130T
Other languages
English (en)
Inventor
Qing Yu
Original Assignee
Shire Biochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Biochem Inc filed Critical Shire Biochem Inc
Application granted granted Critical
Publication of ATE370945T1 publication Critical patent/ATE370945T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AT05017130T 2001-06-15 2002-06-14 Stereoselektives verfahren zur herstellung von nukleosidderivaten ATE370945T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29807901P 2001-06-15 2001-06-15

Publications (1)

Publication Number Publication Date
ATE370945T1 true ATE370945T1 (de) 2007-09-15

Family

ID=23148927

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02742572T ATE313542T1 (de) 2001-06-15 2002-06-14 Stereoselektives verfahren zur herstellung von nukleosidanaloga
AT05017130T ATE370945T1 (de) 2001-06-15 2002-06-14 Stereoselektives verfahren zur herstellung von nukleosidderivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02742572T ATE313542T1 (de) 2001-06-15 2002-06-14 Stereoselektives verfahren zur herstellung von nukleosidanaloga

Country Status (29)

Country Link
US (2) US7109334B2 (de)
EP (2) EP1406896B8 (de)
JP (1) JP4542776B2 (de)
KR (1) KR100832617B1 (de)
CN (1) CN1297553C (de)
AP (1) AP1559A (de)
AT (2) ATE313542T1 (de)
AU (2) AU2002344862C1 (de)
BR (2) BR0210444A (de)
CA (1) CA2449338C (de)
CO (1) CO5550497A2 (de)
CY (1) CY1107805T1 (de)
DE (2) DE60222031T2 (de)
DK (2) DK1632490T3 (de)
EA (1) EA006372B1 (de)
ES (2) ES2293445T3 (de)
HK (1) HK1070652A1 (de)
HR (1) HRP20031021B1 (de)
IL (2) IL159139A0 (de)
MX (1) MXPA03011627A (de)
NO (1) NO326135B1 (de)
NZ (1) NZ529906A (de)
OA (1) OA12628A (de)
PL (2) PL215267B1 (de)
PT (1) PT1632490E (de)
RS (1) RS50868B (de)
SI (2) SI1406896T1 (de)
WO (1) WO2002102796A1 (de)
ZA (1) ZA200309307B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501514B1 (en) 2003-10-15 2009-03-10 Shire Biochem, Inc. Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides
JP4653966B2 (ja) * 2004-04-19 2011-03-16 ダイセル化学工業株式会社 2−ベンゾイルオキシアセトアルデヒド誘導体の製造法
US8318934B2 (en) * 2007-09-28 2012-11-27 Avexa Limited Process for chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes
US20130165350A1 (en) * 2011-12-22 2013-06-27 Affymetrix, Inc. Surface linkers for array synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR840001591A (ko) 1981-09-29 1984-05-07 구라바야시 이꾸시로 당케탈류의 제조방법
EP0560794B1 (de) * 1990-11-13 1996-09-18 Biochem Pharma Inc Substituierte 1,3-oxathiolane mit antiviralen eigenschaften
US5587480A (en) * 1990-11-13 1996-12-24 Biochem Pharma, Inc. Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
US5532349A (en) 1993-07-20 1996-07-02 Mitsui Toatsu Chemicals, Inc. Process for producing 1-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-trifluoromethyluracil derivatives
ES2537540T3 (es) 1998-08-12 2015-06-09 Gilead Sciences, Inc. Método de fabricación de nucleósidos de 1,3-dioxolano y 1,3-oxatiolano

Also Published As

Publication number Publication date
PL218777B1 (pl) 2015-01-30
KR100832617B1 (ko) 2008-05-27
US7109334B2 (en) 2006-09-19
MXPA03011627A (es) 2005-03-07
WO2002102796A1 (en) 2002-12-27
DE60222031D1 (de) 2007-10-04
BR0210444A (pt) 2004-08-17
DK1632490T3 (da) 2008-01-28
EP1406896A1 (de) 2004-04-14
ES2254695T3 (es) 2006-06-16
CO5550497A2 (es) 2005-08-31
AU2008203443B2 (en) 2011-06-16
ATE313542T1 (de) 2006-01-15
WO2002102796A8 (en) 2003-09-18
JP2004535428A (ja) 2004-11-25
HRP20031021B1 (en) 2007-09-30
PL215267B1 (pl) 2013-11-29
OA12628A (en) 2006-06-13
YU97503A (sh) 2006-05-25
US20030135048A1 (en) 2003-07-17
DK1406896T3 (da) 2006-05-08
EA006372B1 (ru) 2005-12-29
RS50868B (sr) 2010-08-31
SI1406896T1 (sl) 2006-04-30
US20060183899A1 (en) 2006-08-17
EP1632490A1 (de) 2006-03-08
KR20040017233A (ko) 2004-02-26
DE60222031T2 (de) 2008-05-21
AU2002344862C1 (en) 2009-02-19
AU2008203443A1 (en) 2008-08-21
AU2002344862B2 (en) 2008-05-01
DE60208202D1 (de) 2006-01-26
US7230100B2 (en) 2007-06-12
IL159139A (en) 2010-04-15
PL401835A1 (pl) 2013-02-18
EP1406896B1 (de) 2005-12-21
CA2449338C (en) 2012-02-07
NZ529906A (en) 2006-03-31
PL366907A1 (en) 2005-02-07
BRPI0210444B1 (pt) 2017-06-20
CN1297553C (zh) 2007-01-31
CN1543463A (zh) 2004-11-03
NO20035556D0 (no) 2003-12-12
NO326135B1 (no) 2008-10-06
ES2293445T3 (es) 2008-03-16
EA200400042A1 (ru) 2004-06-24
DE60208202T2 (de) 2006-08-17
CY1107805T1 (el) 2013-06-19
IL159139A0 (en) 2004-06-01
EP1406896B8 (de) 2006-11-15
CA2449338A1 (en) 2002-12-27
EP1632490B1 (de) 2007-08-22
ZA200309307B (en) 2005-02-23
SI1632490T1 (sl) 2008-02-29
JP4542776B2 (ja) 2010-09-15
HK1070652A1 (en) 2005-06-24
AP1559A (en) 2006-01-24
HRP20031021A2 (en) 2004-06-30
PT1632490E (pt) 2007-11-07

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