HRP20020851A2 - Sodium-hydrogen exchanger type 1 inhibitor (nhe-1) - Google Patents

Sodium-hydrogen exchanger type 1 inhibitor (nhe-1) Download PDF

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Publication number
HRP20020851A2
HRP20020851A2 HR20020851A HRP20020851A HRP20020851A2 HR P20020851 A2 HRP20020851 A2 HR P20020851A2 HR 20020851 A HR20020851 A HR 20020851A HR P20020851 A HRP20020851 A HR P20020851A HR P20020851 A2 HRP20020851 A2 HR P20020851A2
Authority
HR
Croatia
Prior art keywords
compound
tissue
prodrug
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
HR20020851A
Other languages
English (en)
Croatian (hr)
Inventor
George Chen Weichao
David Cox Eric
Guzman-Perez Angel
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HRP20020851A2 publication Critical patent/HRP20020851A2/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20020851A 2000-04-28 2002-10-25 Sodium-hydrogen exchanger type 1 inhibitor (nhe-1) HRP20020851A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28
PCT/IB2001/000277 WO2001083470A1 (en) 2000-04-28 2001-02-28 Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)

Publications (1)

Publication Number Publication Date
HRP20020851A2 true HRP20020851A2 (en) 2005-02-28

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020851A HRP20020851A2 (en) 2000-04-28 2002-10-25 Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)

Country Status (40)

Country Link
EP (1) EP1276737A1 (cs)
JP (1) JP2003531900A (cs)
KR (1) KR20020093079A (cs)
CN (1) CN1225466C (cs)
AP (1) AP2002002651A0 (cs)
AR (1) AR028375A1 (cs)
AU (1) AU2001235896A1 (cs)
BG (1) BG107139A (cs)
BR (1) BR0110268A (cs)
CA (1) CA2407535A1 (cs)
CO (1) CO5221125A1 (cs)
CR (1) CR6797A (cs)
CZ (1) CZ20023408A3 (cs)
DZ (1) DZ3310A1 (cs)
EA (1) EA004882B1 (cs)
EE (1) EE200200615A (cs)
GT (1) GT200100064A (cs)
HN (1) HN2001000042A (cs)
HR (1) HRP20020851A2 (cs)
HU (1) HUP0300651A2 (cs)
IL (1) IL152075A0 (cs)
IS (2) IS6567A (cs)
MA (1) MA26897A1 (cs)
MX (1) MXPA02010600A (cs)
MY (1) MY133842A (cs)
NO (1) NO20025132L (cs)
NZ (1) NZ521348A (cs)
OA (1) OA12256A (cs)
PA (1) PA8513301A1 (cs)
PE (1) PE20011270A1 (cs)
PL (1) PL357765A1 (cs)
SK (1) SK14872002A3 (cs)
SV (1) SV2002000418A (cs)
TN (1) TNSN01065A1 (cs)
TR (1) TR200202439T2 (cs)
UA (1) UA73348C2 (cs)
UY (1) UY26680A1 (cs)
WO (1) WO2001083470A1 (cs)
YU (1) YU79602A (cs)
ZA (1) ZA200208605B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0116841A (pt) * 2001-01-31 2004-02-25 Pfizer Producs Inc Etanolatos de inibidor de permutador sódio-hidrogênio do tipo-1
EP1456181A1 (en) * 2001-12-19 2004-09-15 Pfizer Products Inc. Methods for preparing sodium-hydrogen exchanger type-1 inhibitors
MXPA04008646A (es) * 2002-05-02 2004-12-06 Pfizer Prod Inc Tratamiento para la diabetes y complicaciones diabeticas con inhibidores del nhe-1.
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
ES2220185B1 (es) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas Nuevo peptido inhibidor del intercambiador na+/h+ (pinhe), y sus aplicaciones.
US7550480B2 (en) * 2003-02-14 2009-06-23 Smithkline Beecham Corporation Compounds
RU2518741C1 (ru) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" СРЕДСТВО, ИНГИБИРУЮЩЕЕ Na+/H+-ОБМЕН, И ГАЛОГЕНИДЫ 1-ДИАЛКИЛАМИНОЭТИЛ-3-[ЗАМЕЩЕННЫЙ(ДИЗАМЕЩЕННЫЙ) ФЕНАЦИЛ]-2-АМИНОБЕНЗИМИДАЗОЛИЯ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU46200A (sh) * 1998-02-27 2003-02-28 Pfizer Products Inc. N-(supstituisani peto-članog di-ili triaza dinezasićenog prstena)karbonil/guanidin derivati za tretiranje ishemije

Also Published As

Publication number Publication date
KR20020093079A (ko) 2002-12-12
PE20011270A1 (es) 2001-12-12
TNSN01065A1 (fr) 2005-11-10
EP1276737A1 (en) 2003-01-22
HN2001000042A (es) 2001-07-09
UA73348C2 (en) 2005-07-15
CA2407535A1 (en) 2001-11-08
NO20025132D0 (no) 2002-10-25
EE200200615A (et) 2004-04-15
WO2001083470A1 (en) 2001-11-08
JP2003531900A (ja) 2003-10-28
IS6588A (is) 2002-10-21
MY133842A (en) 2007-11-30
CZ20023408A3 (cs) 2004-01-14
BR0110268A (pt) 2003-12-30
OA12256A (en) 2003-11-06
IS6567A (is) 2002-09-24
ZA200208605B (en) 2003-10-24
BG107139A (bg) 2003-07-31
CR6797A (es) 2004-05-17
AR028375A1 (es) 2003-05-07
MXPA02010600A (es) 2003-03-10
PL357765A1 (en) 2004-07-26
EA004882B1 (ru) 2004-08-26
TR200202439T2 (tr) 2003-02-21
MA26897A1 (fr) 2004-12-20
YU79602A (en) 2006-05-25
NZ521348A (en) 2004-09-24
SK14872002A3 (sk) 2004-03-02
UY26680A1 (es) 2001-12-28
NO20025132L (no) 2002-12-12
CO5221125A1 (es) 2002-11-28
DZ3310A1 (fr) 2001-11-07
SV2002000418A (es) 2002-07-03
CN1426404A (zh) 2003-06-25
PA8513301A1 (es) 2003-09-05
AU2001235896A1 (en) 2001-11-12
GT200100064A (es) 2002-03-22
CN1225466C (zh) 2005-11-02
EA200201023A1 (ru) 2003-02-27
AP2002002651A0 (en) 2002-12-31
HUP0300651A2 (hu) 2003-07-28
IL152075A0 (en) 2003-05-29

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