HRP20020609B1 - Process for rapid solution syntheses of peptides - Google Patents

Process for rapid solution syntheses of peptides

Info

Publication number
HRP20020609B1
HRP20020609B1 HR20020609A HRP20020609A HRP20020609B1 HR P20020609 B1 HRP20020609 B1 HR P20020609B1 HR 20020609 A HR20020609 A HR 20020609A HR P20020609 A HRP20020609 A HR P20020609A HR P20020609 B1 HRP20020609 B1 HR P20020609B1
Authority
HR
Croatia
Prior art keywords
peptides
rapid solution
solution syntheses
syntheses
rapid
Prior art date
Application number
HR20020609A
Other languages
English (en)
Inventor
Franci Eggen Ivo
Bernardus Wilhelmus Ten Kortenaar Paulus
Albert Gruson Haasnoot Cornelis
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HRP20020609A2 publication Critical patent/HRP20020609A2/hr
Publication of HRP20020609B1 publication Critical patent/HRP20020609B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HR20020609A 2001-07-19 2002-07-19 Process for rapid solution syntheses of peptides HRP20020609B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202753 2001-07-19

Publications (2)

Publication Number Publication Date
HRP20020609A2 HRP20020609A2 (en) 2003-02-28
HRP20020609B1 true HRP20020609B1 (en) 2005-06-30

Family

ID=8180656

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020609A HRP20020609B1 (en) 2001-07-19 2002-07-19 Process for rapid solution syntheses of peptides

Country Status (26)

Country Link
US (4) US20030018164A1 (he)
EP (1) EP1291356B1 (he)
JP (1) JP4142907B2 (he)
KR (1) KR100861031B1 (he)
CN (1) CN1254483C (he)
AR (1) AR034869A1 (he)
AT (1) ATE302792T1 (he)
BR (1) BRPI0202783B1 (he)
CA (1) CA2390358C (he)
DE (1) DE60205693T2 (he)
DK (1) DK1291356T3 (he)
EC (1) ECSP024291A (he)
ES (1) ES2248485T3 (he)
HK (1) HK1050904A1 (he)
HR (1) HRP20020609B1 (he)
HU (1) HUP0202369A2 (he)
IL (1) IL150601A (he)
MX (1) MXPA02006998A (he)
NO (1) NO324245B1 (he)
PE (1) PE20030214A1 (he)
PL (1) PL205559B1 (he)
PT (1) PT1291356E (he)
RU (1) RU2237673C2 (he)
SG (1) SG119160A1 (he)
TW (1) TWI247012B (he)
ZA (1) ZA200205409B (he)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150601A (he) * 2001-07-19 2010-06-30 Organon Nv תהליך לסינתזה מהירה של פפטידים בתוך תמיסה באמצעות שימוש בעורף מרכיב קרבוקסילי משופעל והשמדת המרכיב הקרבוקסילי המשופעל השאריתי
EP1790656A1 (en) * 2005-11-25 2007-05-30 Nanokem S.A. Solution-phase synthesis of leuprolide
EP1801086A1 (en) * 2005-11-25 2007-06-27 Synthacon GmbH Synthesis of carbon acid amides
EP1979370B1 (en) * 2006-01-17 2010-03-17 N.V. Organon SELECTIVE ENZYMATIC HYDROLYSIS OF C-TERMINAL tert-BUTYL ESTERS OF PEPTIDES
WO2007099656A1 (ja) 2006-03-01 2007-09-07 Kaneka Corporation ペプチドの製造方法
US8124372B2 (en) 2007-06-25 2012-02-28 N.V. Organon Selective enzymatic amidation of C-terminal esters or acids of peptides
WO2009000814A1 (en) * 2007-06-25 2008-12-31 N.V. Organon Process for the conversion of c-terminal peptide esters or acids to amides employing subtilisin in the presence of ammonium salts
RU2482127C2 (ru) * 2008-12-30 2013-05-20 Гкл-Биотек Аг Комбинация пептидов
KR101032399B1 (ko) * 2010-02-11 2011-05-03 주식회사 이너트론 밴드패스필터의 철재하우징 및 그 제조방법
EP2409982A3 (en) * 2010-02-25 2012-02-08 Corning Incorporated Chemical processes generating solid(s) carried out continuously within microreactors
JP6136934B2 (ja) 2011-12-15 2017-05-31 味の素株式会社 Ｆｍｏｃ基の除去方法
CN107406480B (zh) 2015-03-04 2022-06-24 Jitsubo株式会社 肽合成方法
ES2957399T3 (es) 2018-04-13 2024-01-18 Jitsubo Co Ltd Método de síntesis de péptidos
US12024537B2 (en) 2018-05-31 2024-07-02 Sederma Compositions and methods for chemical synthesis
FR3090636B1 (fr) * 2018-12-24 2021-01-01 Strainchem Procédé de synthèse de peptides
CA3126705A1 (en) 2019-02-01 2020-08-06 Gap Peptides Llc Synthesis strategy for gap protecting group
TW202138382A (zh) 2019-12-27 2021-10-16 日商中外製藥股份有限公司 胜肽化合物的合成法
CN115362144A (zh) * 2020-03-27 2022-11-18 株式会社钟化 含酰胺键化合物的制造方法
JP7063408B1 (ja) 2021-07-02 2022-05-09 ペプチスター株式会社 液相ペプチド製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1991A (en) * 1841-02-23 Manner of fastening bedsteads
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
US5101059A (en) * 1989-12-05 1992-03-31 Research Corporation Technologies, Inc. Amino acid protecting groups
US5877278A (en) * 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5516892A (en) * 1992-12-28 1996-05-14 Indiana University Foundation Polymer-bound mixed carboxylic anhdrides as a stable form of activated carboxylic acids
US6310180B1 (en) * 1993-06-21 2001-10-30 Vanderbilt University Method for synthesis of proteins
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US6001966A (en) * 1995-10-19 1999-12-14 Proligo Llc Method for solution phase synthesis of oligonucleotides and peptides
US5698676A (en) * 1995-11-30 1997-12-16 Abbott Laboratories Use of propylene oxide as an acid scavenger in peptide synthesis
US5849954A (en) * 1996-01-18 1998-12-15 Research Corporation Technologies, Inc. Method of peptide synthesis
US6306959B1 (en) * 1996-05-03 2001-10-23 Warner Lambert Company Rapid purification by polymer supported quench
US6121488A (en) * 1997-09-24 2000-09-19 Warner-Lambert Company Quenching reagents for solution phase synthesis
JPH11217397A (ja) * 1997-11-27 1999-08-10 Saburo Aimoto ペプチドチオールエステルの製造方法
FR2780061B1 (fr) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
EP1180115A1 (en) * 1999-05-26 2002-02-20 Abbott Laboratories Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents
US20020127219A1 (en) * 1999-12-30 2002-09-12 Okkels Jens Sigurd Lysosomal enzymes and lysosomal enzyme activators
IL153943A0 (en) * 2000-07-19 2003-07-31 Upjohn Co SUBSTRATES AND ASSAYS FOR beta-SECRETASE ACTIVITY
IL150601A (he) * 2001-07-19 2010-06-30 Organon Nv תהליך לסינתזה מהירה של פפטידים בתוך תמיסה באמצעות שימוש בעורף מרכיב קרבוקסילי משופעל והשמדת המרכיב הקרבוקסילי המשופעל השאריתי
IL150600A (en) * 2001-07-19 2005-09-25 Akzo Nobel Nv Process for the preparation of compounds containing one or more amide bonds using an excess of an activated carboxylic component and scavenging the residual activated carboxylic component
US7893187B2 (en) * 2005-06-17 2011-02-22 Eastman Chemical Company Glass laminates comprising polyester compositions formed from 2,2,4,4-tetramethyl-1,3-cyclobutanediol and 1,4-cyclohexanedimethanol

Also Published As

Publication number Publication date
HK1050904A1 (en) 2003-07-11
ES2248485T3 (es) 2006-03-16
TWI247012B (en) 2006-01-11
US20030018164A1 (en) 2003-01-23
NO20023446L (no) 2003-01-20
BR0202783A (pt) 2003-06-10
NO20023446D0 (no) 2002-07-18
KR20030009188A (ko) 2003-01-29
ECSP024291A (es) 2002-09-27
DE60205693T2 (de) 2006-06-14
PE20030214A1 (es) 2003-03-17
PL355125A1 (en) 2003-01-27
IL150601A (he) 2010-06-30
HRP20020609A2 (en) 2003-02-28
EP1291356A2 (en) 2003-03-12
NO324245B1 (no) 2007-09-17
DE60205693D1 (de) 2005-09-29
SG119160A1 (en) 2006-02-28
HU0202369D0 (he) 2002-09-28
US20040087768A1 (en) 2004-05-06
EP1291356B1 (en) 2005-08-24
HUP0202369A2 (en) 2006-08-28
DK1291356T3 (da) 2005-12-19
EP1291356A3 (en) 2004-01-02
PT1291356E (pt) 2005-11-30
JP2003055396A (ja) 2003-02-26
KR100861031B1 (ko) 2008-10-01
US7435791B2 (en) 2008-10-14
CN1254483C (zh) 2006-05-03
IL150601A0 (en) 2003-02-12
JP4142907B2 (ja) 2008-09-03
ATE302792T1 (de) 2005-09-15
ZA200205409B (en) 2002-09-05
AR034869A1 (es) 2004-03-24
CA2390358C (en) 2004-12-21
CA2390358A1 (en) 2003-01-19
CN1398876A (zh) 2003-02-26
MXPA02006998A (es) 2005-02-17
US20040082760A1 (en) 2004-04-29
RU2237673C2 (ru) 2004-10-10
PL205559B1 (pl) 2010-05-31
BRPI0202783B1 (pt) 2016-07-05
RU2002119630A (ru) 2004-01-20
US20060063918A1 (en) 2006-03-23

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
PPPP Transfer of rights

Owner name: N.V. ORGANON, NL

ODRP Renewal fee for the maintenance of a patent

Payment date: 20090710

Year of fee payment: 8

PBON Lapse due to non-payment of renewal fee

Effective date: 20100720