HRP20010904A2 - Polymorphs of a crystalline azabicyclo[2,2,2]octan-3-amine citrate and their pharmaceutical compositions - Google Patents

Polymorphs of a crystalline azabicyclo[2,2,2]octan-3-amine citrate and their pharmaceutical compositions Download PDF

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Publication number
HRP20010904A2
HRP20010904A2 HR20010904A HRP20010904A HRP20010904A2 HR P20010904 A2 HRP20010904 A2 HR P20010904A2 HR 20010904 A HR20010904 A HR 20010904A HR P20010904 A HRP20010904 A HR P20010904A HR P20010904 A2 HRP20010904 A2 HR P20010904A2
Authority
HR
Croatia
Prior art keywords
polymorphic form
approximately
citrate
crystalline
hours
Prior art date
Application number
HR20010904A
Other languages
English (en)
Croatian (hr)
Inventor
Michael James Castaldi
George Joseph Quallich
Lewin Theophilus Wint
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HRP20010904A2 publication Critical patent/HRP20010904A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20010904A 1999-06-01 2000-05-18 Polymorphs of a crystalline azabicyclo[2,2,2]octan-3-amine citrate and their pharmaceutical compositions HRP20010904A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13699299P 1999-06-01 1999-06-01
PCT/IB2000/000665 WO2000073304A1 (en) 1999-06-01 2000-05-18 Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions

Publications (1)

Publication Number Publication Date
HRP20010904A2 true HRP20010904A2 (en) 2003-02-28

Family

ID=22475338

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010904A HRP20010904A2 (en) 1999-06-01 2000-05-18 Polymorphs of a crystalline azabicyclo[2,2,2]octan-3-amine citrate and their pharmaceutical compositions

Country Status (48)

Country Link
US (1) US6255320B1 (cs)
EP (1) EP1181290B1 (cs)
JP (1) JP3830816B2 (cs)
KR (1) KR100476606B1 (cs)
CN (1) CN1146565C (cs)
AP (1) AP2001002349A0 (cs)
AR (1) AR033331A1 (cs)
AT (1) ATE244239T1 (cs)
AU (1) AU767334B2 (cs)
BG (1) BG65240B1 (cs)
BR (1) BR0011094A (cs)
CA (1) CA2372238C (cs)
CO (1) CO5170463A1 (cs)
CY (1) CY2007011I1 (cs)
CZ (1) CZ295819B6 (cs)
DE (1) DE60003679T2 (cs)
DK (1) DK1181290T3 (cs)
DZ (1) DZ3050A1 (cs)
EA (1) EA003731B1 (cs)
EC (1) ECSP003508A (cs)
EE (1) EE200100656A (cs)
ES (1) ES2199825T3 (cs)
GT (1) GT200000087A (cs)
HN (1) HN2000000077A (cs)
HR (1) HRP20010904A2 (cs)
HU (1) HUP0201301A3 (cs)
IL (1) IL146406A0 (cs)
MA (1) MA26742A1 (cs)
MX (1) MXPA01012325A (cs)
MY (1) MY133508A (cs)
NO (1) NO20015848L (cs)
NZ (1) NZ515349A (cs)
OA (1) OA11956A (cs)
PA (1) PA8496101A1 (cs)
PE (1) PE20010209A1 (cs)
PL (1) PL196046B1 (cs)
PT (1) PT1181290E (cs)
SI (1) SI1181290T1 (cs)
SK (1) SK285820B6 (cs)
SV (1) SV2001000093A (cs)
TN (1) TNSN00120A1 (cs)
TR (1) TR200103473T2 (cs)
TW (1) TWI285204B (cs)
UA (1) UA66925C2 (cs)
UY (1) UY26176A1 (cs)
WO (1) WO2000073304A1 (cs)
YU (1) YU81101A (cs)
ZA (1) ZA200109775B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1713504T1 (sl) * 2004-01-30 2017-10-30 Zoetis Services Llc Protimikrobni konzervansi za dosego večodmerne formulacije z uporabo beta-ciklodekstrinov za tekoče odmerne oblike
BRPI0507301A (pt) * 2004-01-30 2007-06-26 Pfizer Prod Inc composições farmacêuticas de antagonistas do receptor de nuerocinina e ciclodextrina e métodos para melhor toleráncia no local de injeção
BRPI0507325A (pt) * 2004-01-30 2007-07-03 Pfizer Prod Inc antagonistas dos receptores nk-1 para melhorar a recuperação da anestesia
DE602005003791T2 (de) * 2004-02-02 2008-05-29 Pfizer Products Inc., Groton Verfahren zur herstellung von 1-(2s,3s)-2-benzhydril-n-(5-tert.-butyl-2-methoxybenzyl)chinuklidin-3-amin
RU2696582C2 (ru) * 2013-03-15 2019-08-05 Перл Терапьютикс, Инк. Способы и системы кондиционирования дисперсных кристаллических материалов
CN110577522B (zh) * 2018-06-07 2022-12-27 东莞市东阳光动物保健药品有限公司 马罗匹坦柠檬酸盐新晶型及其制备方法
CN112979639B (zh) * 2019-12-16 2025-08-08 凯默斯医药科技(上海)有限公司 一种马罗皮坦新晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2102179C (en) * 1991-05-31 1998-10-27 Fumitaka Ito Quinuclidine derivatives
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
US5576317A (en) * 1994-12-09 1996-11-19 Pfizer Inc. NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis

Also Published As

Publication number Publication date
EE200100656A (et) 2003-02-17
ATE244239T1 (de) 2003-07-15
NO20015848D0 (no) 2001-11-30
HN2000000077A (es) 2001-02-02
PA8496101A1 (es) 2002-07-30
SK17332001A3 (sk) 2002-07-02
TNSN00120A1 (fr) 2005-11-10
CA2372238A1 (en) 2000-12-07
JP2003501354A (ja) 2003-01-14
AP2001002349A0 (en) 2001-12-31
PE20010209A1 (es) 2001-03-01
GT200000087A (es) 2001-11-22
TR200103473T2 (tr) 2002-04-22
CZ20014269A3 (cs) 2002-04-17
SV2001000093A (es) 2001-11-08
SK285820B6 (sk) 2007-09-06
US6255320B1 (en) 2001-07-03
TWI285204B (en) 2007-08-11
MXPA01012325A (es) 2002-07-22
MA26742A1 (fr) 2004-12-20
YU81101A (sh) 2004-07-15
ECSP003508A (es) 2002-02-25
CA2372238C (en) 2006-12-19
AR033331A1 (es) 2003-12-17
EP1181290A1 (en) 2002-02-27
AU767334B2 (en) 2003-11-06
IL146406A0 (en) 2002-07-25
MY133508A (en) 2007-11-30
CO5170463A1 (es) 2002-06-27
KR100476606B1 (ko) 2005-03-18
PL196046B1 (pl) 2007-11-30
EA200101108A1 (ru) 2002-04-25
BR0011094A (pt) 2002-03-19
CN1353711A (zh) 2002-06-12
DK1181290T3 (da) 2003-09-29
EA003731B1 (ru) 2003-08-28
JP3830816B2 (ja) 2006-10-11
CN1146565C (zh) 2004-04-21
PT1181290E (pt) 2003-09-30
AU4424800A (en) 2000-12-18
CY2007011I2 (el) 2010-07-28
CY2007011I1 (el) 2010-07-28
DE60003679T2 (de) 2004-05-27
EP1181290B1 (en) 2003-07-02
ES2199825T3 (es) 2004-03-01
SI1181290T1 (en) 2003-12-31
HK1046284A1 (en) 2003-01-03
NO20015848L (no) 2001-12-18
DZ3050A1 (fr) 2004-03-27
PL352716A1 (en) 2003-09-08
UA66925C2 (uk) 2004-06-15
DE60003679D1 (de) 2003-08-07
WO2000073304A1 (en) 2000-12-07
BG65240B1 (bg) 2007-09-28
HUP0201301A2 (en) 2002-08-28
NZ515349A (en) 2004-03-26
UY26176A1 (es) 2000-12-29
HUP0201301A3 (en) 2002-10-28
ZA200109775B (en) 2002-11-28
BG106204A (en) 2002-07-31
CZ295819B6 (cs) 2005-11-16
OA11956A (en) 2006-04-13
KR20020010688A (ko) 2002-02-04

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