HN2005000508A - Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas - Google Patents

Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas

Info

Publication number
HN2005000508A
HN2005000508A HN2005000508A HN2005000508A HN2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A
Authority
HN
Honduras
Prior art keywords
substituted
preparation
processes
dixopiperidin
oxoisoindolines
Prior art date
Application number
HN2005000508A
Other languages
English (en)
Spanish (es)
Inventor
W Muller George
Chen Roger
Tukaram Saindane Manohar
Ge Chuansheng
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35385616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HN2005000508(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of HN2005000508A publication Critical patent/HN2005000508A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HN2005000508A 2004-09-03 2005-09-02 Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas HN2005000508A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60740904P 2004-09-03 2004-09-03

Publications (1)

Publication Number Publication Date
HN2005000508A true HN2005000508A (es) 2010-10-08

Family

ID=35385616

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2005000508A HN2005000508A (es) 2004-09-03 2005-09-02 Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas

Country Status (22)

Country Link
US (1) US7863451B2 (https=)
EP (2) EP2479172B1 (https=)
JP (2) JP2008512379A (https=)
KR (1) KR20070057907A (https=)
CN (1) CN101080400A (https=)
AR (1) AR050724A1 (https=)
AU (1) AU2005282728A1 (https=)
BR (1) BRPI0514865A (https=)
CA (1) CA2579291C (https=)
ES (2) ES2437592T3 (https=)
GT (1) GT200500242A (https=)
HN (1) HN2005000508A (https=)
IL (1) IL181674A0 (https=)
MX (1) MX2007002521A (https=)
NZ (1) NZ554068A (https=)
PA (1) PA8643901A1 (https=)
PE (1) PE20060648A1 (https=)
SV (1) SV2007002219A (https=)
TW (1) TW200621748A (https=)
UY (1) UY29097A1 (https=)
WO (1) WO2006028964A1 (https=)
ZA (1) ZA200702382B (https=)

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DE102008057284A1 (de) 2008-11-14 2010-05-20 Ratiopharm Gmbh Tabletten enthaltend Lenalidomid und Adhäsionsverstärker
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WO2011050962A1 (en) 2009-10-29 2011-05-05 Ratiopharm Gmbh Acid addition salts of lenalidomide
CN102060842B (zh) * 2009-11-02 2013-05-08 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
CN102127054B (zh) * 2009-11-02 2013-04-03 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
CN101696205B (zh) * 2009-11-02 2011-10-19 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
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CN101817813B (zh) * 2010-01-15 2013-04-10 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮晶体ⅳ及其药用组合物
EP2536706B1 (en) * 2010-02-11 2017-06-14 Celgene Corporation Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
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CN111205268B (zh) * 2014-10-30 2021-01-26 康朴生物医药技术（上海）有限公司 异吲哚啉衍生物、其中间体、制备方法、药物组合物及应用
CN104447689B (zh) * 2014-12-22 2016-07-20 上海迈柏医药科技有限公司 来那度胺的晶型及其制备方法
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
CN108191826A (zh) * 2018-01-08 2018-06-22 浙江省医学科学院 一种来那度胺晶体及其制备方法
CN118344338A (zh) 2018-04-23 2024-07-16 细胞基因公司 取代的4-氨基异吲哚啉-1,3-二酮化合物以及它们用于治疗淋巴瘤的用途
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WO2020048546A1 (zh) * 2018-09-07 2020-03-12 南京明德新药研发有限公司 三环取代哌啶二酮类化合物
JP2022507267A (ja) 2018-11-13 2022-01-18 バイオセリックス， インコーポレイテッド 置換イソインドリノン
CN109369504B (zh) * 2018-12-06 2020-05-12 温州大学 含硫3-亚甲基异吲哚啉-1-酮衍生物的制备方法
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Also Published As

Publication number Publication date
EP2479172B1 (en) 2013-10-09
BRPI0514865A (pt) 2008-06-24
JP5701824B2 (ja) 2015-04-15
EP2479172A1 (en) 2012-07-25
CA2579291A1 (en) 2006-03-16
PE20060648A1 (es) 2006-07-14
EP1797068B1 (en) 2013-10-09
TW200621748A (en) 2006-07-01
IL181674A0 (en) 2007-07-04
ES2437592T3 (es) 2014-01-13
NZ554068A (en) 2009-07-31
CA2579291C (en) 2011-11-29
US7863451B2 (en) 2011-01-04
CN101080400A (zh) 2007-11-28
ZA200702382B (en) 2008-08-27
KR20070057907A (ko) 2007-06-07
EP1797068A1 (en) 2007-06-20
ES2438725T3 (es) 2014-01-20
AR050724A1 (es) 2006-11-15
JP2008512379A (ja) 2008-04-24
SV2007002219A (es) 2007-03-20
GT200500242A (es) 2006-06-22
UY29097A1 (es) 2006-03-31
PA8643901A1 (es) 2006-05-16
JP2012207040A (ja) 2012-10-25
AU2005282728A1 (en) 2006-03-16
US20060052609A1 (en) 2006-03-09
MX2007002521A (es) 2007-05-09
WO2006028964A1 (en) 2006-03-16

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