MXPA04006031A - Compuestos para el tratamiento de trastornos inflamatorios. - Google Patents

Compuestos para el tratamiento de trastornos inflamatorios.

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Publication number
MXPA04006031A
MXPA04006031A MXPA04006031A MXPA04006031A MXPA04006031A MX PA04006031 A MXPA04006031 A MX PA04006031A MX PA04006031 A MXPA04006031 A MX PA04006031A MX PA04006031 A MXPA04006031 A MX PA04006031A MX PA04006031 A MXPA04006031 A MX PA04006031A
Authority
MX
Mexico
Prior art keywords
compounds
treatment
inflammatory disorders
formula
mmps
Prior art date
Application number
MXPA04006031A
Other languages
English (en)
Inventor
Neng-Yang Shih
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MXPA04006031A publication Critical patent/MXPA04006031A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
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    • A61K31/16—Amides, e.g. hydroxamic acids
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Abstract

La invencion se refiere a compuestos de la formula (I): (Ver formula I) o una sal, un solvato o un isomero farmaceuticamente aceptable de los mismos, que pueden ser utiles para el tratamiento de enfermedades o condiciones mediadas por las MMP, el TNF-a o sus combinaciones.
MXPA04006031A 2001-12-20 2002-12-19 Compuestos para el tratamiento de trastornos inflamatorios. MXPA04006031A (es)

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PCT/US2002/040453 WO2003053915A2 (en) 2001-12-20 2002-12-19 Compounds for the treatment of inflammatory disorders

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CN1620424A (zh) 2005-05-25
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HUP0500016A2 (hu) 2005-04-28
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