UA98772C2 - Производные циклопропиламина как модуляторы н3-гистаминового рецептора - Google Patents
Производные циклопропиламина как модуляторы н3-гистаминового рецептораInfo
- Publication number
- UA98772C2 UA98772C2 UAA200900472A UAA200900472A UA98772C2 UA 98772 C2 UA98772 C2 UA 98772C2 UA A200900472 A UAA200900472 A UA A200900472A UA A200900472 A UAA200900472 A UA A200900472A UA 98772 C2 UA98772 C2 UA 98772C2
- Authority
- UA
- Ukraine
- Prior art keywords
- histamin
- receptor modulators
- amine derivatives
- cyclopropyl amine
- compounds
- Prior art date
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Соединения формулы (I)(I),полезны при лечении состояний или нарушений, которые предотвращают или которые облегчают с помощью лигандов Н-гистаминовых рецепторов.Также раскрыты фармацевтические композиции, которые содержат лиганды Н-гистаминовых рецепторов, применение таких соединений и композиций и способ получения соединений, которые входят в область, которая определяется формулой (I).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81593406P | 2006-06-23 | 2006-06-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA98772C2 true UA98772C2 (ru) | 2012-06-25 |
Family
ID=38670977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200900472A UA98772C2 (ru) | 2006-06-23 | 2007-06-22 | Производные циклопропиламина как модуляторы н3-гистаминового рецептора |
Country Status (22)
Country | Link |
---|---|
US (1) | US8829041B2 (ru) |
EP (1) | EP2049472B1 (ru) |
JP (1) | JP5203360B2 (ru) |
KR (1) | KR20090024811A (ru) |
CN (2) | CN103382174A (ru) |
AU (1) | AU2007260836B2 (ru) |
BR (1) | BRPI0712823A2 (ru) |
CA (1) | CA2655604C (ru) |
CR (1) | CR10540A (ru) |
DO (1) | DOP2011000283A (ru) |
EC (1) | ECSP099046A (ru) |
ES (1) | ES2533009T3 (ru) |
IL (1) | IL196094A0 (ru) |
MX (1) | MX2008016343A (ru) |
NO (1) | NO20090282L (ru) |
NZ (2) | NZ611323A (ru) |
RU (1) | RU2449989C2 (ru) |
SG (1) | SG173312A1 (ru) |
TW (1) | TW200808773A (ru) |
UA (1) | UA98772C2 (ru) |
UY (1) | UY31527A1 (ru) |
WO (1) | WO2007150010A2 (ru) |
Families Citing this family (10)
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JP4981794B2 (ja) * | 2005-06-03 | 2012-07-25 | アボット・ラボラトリーズ | シクロブチルアミン誘導体 |
US9108948B2 (en) * | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
CN103382174A (zh) | 2006-06-23 | 2013-11-06 | 雅培制药有限公司 | 作为组胺h3受体调节物的环丙胺衍生物 |
PT2195293E (pt) | 2007-08-22 | 2014-01-21 | Astrazeneca Ab | Derivados da ciclopropilamida |
AU2013216616B2 (en) * | 2007-12-14 | 2016-04-21 | Abbvie Bahamas Ltd. | Cyclopropyl amine derivatives |
TW201039825A (en) * | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
US9186353B2 (en) * | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
AU2011218490B9 (en) * | 2010-02-18 | 2014-12-18 | Astrazeneca Ab | Solid forms comprising a cyclopropyl amide derivative |
RU2012136148A (ru) | 2010-02-18 | 2014-03-27 | Астразенека Аб | Новая кристаллическая форма производного циклопропилбензамида |
WO2012037258A1 (en) | 2010-09-16 | 2012-03-22 | Abbott Laboratories | Processes for preparing 1,2-substituted cyclopropyl derivatives |
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-
2007
- 2007-06-22 CN CN2013102935381A patent/CN103382174A/zh active Pending
- 2007-06-22 WO PCT/US2007/071849 patent/WO2007150010A2/en active Application Filing
- 2007-06-22 JP JP2009516740A patent/JP5203360B2/ja not_active Expired - Fee Related
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- 2007-06-22 MX MX2008016343A patent/MX2008016343A/es active IP Right Grant
- 2007-06-22 US US11/766,987 patent/US8829041B2/en not_active Expired - Fee Related
- 2007-06-22 ES ES07784511.3T patent/ES2533009T3/es active Active
- 2007-06-22 CN CNA2007800231964A patent/CN101472887A/zh active Pending
- 2007-06-22 BR BRPI0712823-1A patent/BRPI0712823A2/pt not_active IP Right Cessation
- 2007-06-22 EP EP07784511.3A patent/EP2049472B1/en active Active
- 2007-06-22 UA UAA200900472A patent/UA98772C2/ru unknown
- 2007-06-22 TW TW096122533A patent/TW200808773A/zh unknown
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- 2007-06-22 CA CA2655604A patent/CA2655604C/en not_active Expired - Fee Related
- 2007-06-22 KR KR1020097001505A patent/KR20090024811A/ko not_active Application Discontinuation
- 2007-06-22 SG SG2011045200A patent/SG173312A1/en unknown
- 2007-06-22 NZ NZ597498A patent/NZ597498A/xx not_active IP Right Cessation
- 2007-06-22 RU RU2009102048/04A patent/RU2449989C2/ru not_active IP Right Cessation
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- 2008-12-19 CR CR10540A patent/CR10540A/es not_active Application Discontinuation
- 2008-12-21 IL IL196094A patent/IL196094A0/en unknown
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UY31527A1 (es) | 2009-08-03 |
NO20090282L (no) | 2009-03-19 |
CR10540A (es) | 2009-02-05 |
RU2009102048A (ru) | 2010-07-27 |
WO2007150010A3 (en) | 2008-05-02 |
JP5203360B2 (ja) | 2013-06-05 |
EP2049472B1 (en) | 2015-01-21 |
MX2008016343A (es) | 2009-01-19 |
JP2009541350A (ja) | 2009-11-26 |
RU2449989C2 (ru) | 2012-05-10 |
CN101472887A (zh) | 2009-07-01 |
AU2007260836A1 (en) | 2007-12-27 |
CN103382174A (zh) | 2013-11-06 |
ES2533009T3 (es) | 2015-04-06 |
SG173312A1 (en) | 2011-08-29 |
WO2007150010A2 (en) | 2007-12-27 |
CA2655604A1 (en) | 2007-12-27 |
KR20090024811A (ko) | 2009-03-09 |
US20080021081A1 (en) | 2008-01-24 |
US8829041B2 (en) | 2014-09-09 |
EP2049472A2 (en) | 2009-04-22 |
ECSP099046A (es) | 2009-02-27 |
CA2655604C (en) | 2016-08-09 |
NZ597498A (en) | 2013-06-28 |
IL196094A0 (en) | 2009-09-01 |
BRPI0712823A2 (pt) | 2012-07-24 |
NZ611323A (en) | 2014-10-31 |
TW200808773A (en) | 2008-02-16 |
DOP2011000283A (es) | 2011-10-31 |
AU2007260836B2 (en) | 2012-11-15 |
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