HN2005000508A - Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas - Google Patents

Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas

Info

Publication number
HN2005000508A
HN2005000508A HN2005000508A HN2005000508A HN2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A HN 2005000508 A HN2005000508 A HN 2005000508A
Authority
HN
Honduras
Prior art keywords
substituted
preparation
processes
dixopiperidin
oxoisoindolines
Prior art date
Application number
HN2005000508A
Other languages
English (en)
Inventor
W Muller George
Chen Roger
Tukaram Saindane Manohar
Ge Chuansheng
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35385616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HN2005000508(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of HN2005000508A publication Critical patent/HN2005000508A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

ESTA INVENCION SE REFIERE A NUEVOS PROCESOS PARA LA PREPARACION DE 2-(2,6-DIOXOPIPERIDIN-3-JL)-1-OXOISOINDOLINAS SUSTITUIDAS LAS CUALES SON UTILES PARA LA PREVENCION O TRATAMIENTO DE ENFERMEDADES O CONDICIONES RELACIONADAS CON UN NIVEL O ACTIVIDAD ANORMALMENTE ALTOS DE TNT-A LA INVENCION PROPORCIONA PROCESO PARA LA PRODUCCION COMERCIAL DE 2-(2,6-DIOXOPIPERIDIN-3-JL)-1- OXOIISOINDOLINAS SUSTITUIDAS QUE INCLUYEN, PERO NO SE IRRITAN A, LA 3-(-4AMINO-1OXOISOINDOLIN-2-JL)-PIPERIDIN-2,6-DIONA TERAPEUTICAMENTE ACTIVA.
HN2005000508A 2004-09-03 2005-09-02 Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas HN2005000508A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60740904P 2004-09-03 2004-09-03

Publications (1)

Publication Number Publication Date
HN2005000508A true HN2005000508A (es) 2010-10-08

Family

ID=35385616

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2005000508A HN2005000508A (es) 2004-09-03 2005-09-02 Procesos para la preparacion de 2-(2,6-dixopiperidin-3-il)-1-oxoisoindolinas sustituidas

Country Status (22)

Country Link
US (1) US7863451B2 (es)
EP (2) EP2479172B1 (es)
JP (2) JP2008512379A (es)
KR (1) KR20070057907A (es)
CN (1) CN101080400A (es)
AR (1) AR050724A1 (es)
AU (1) AU2005282728A1 (es)
BR (1) BRPI0514865A (es)
CA (1) CA2579291C (es)
ES (2) ES2437592T3 (es)
GT (1) GT200500242A (es)
HN (1) HN2005000508A (es)
IL (1) IL181674A0 (es)
MX (1) MX2007002521A (es)
NZ (1) NZ554068A (es)
PA (1) PA8643901A1 (es)
PE (1) PE20060648A1 (es)
SV (1) SV2007002219A (es)
TW (1) TW200621748A (es)
UY (1) UY29097A1 (es)
WO (1) WO2006028964A1 (es)
ZA (1) ZA200702382B (es)

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PL2477973T3 (pl) * 2009-09-16 2015-04-30 Ranbaxy Laboratories Ltd Sposób wytwarzania krystalicznej formy lenalidomidu
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WO2011050962A1 (en) 2009-10-29 2011-05-05 Ratiopharm Gmbh Acid addition salts of lenalidomide
CN102060842B (zh) * 2009-11-02 2013-05-08 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
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CN102127054B (zh) * 2009-11-02 2013-04-03 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
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Also Published As

Publication number Publication date
WO2006028964A1 (en) 2006-03-16
ZA200702382B (en) 2008-08-27
NZ554068A (en) 2009-07-31
JP2008512379A (ja) 2008-04-24
PE20060648A1 (es) 2006-07-14
TW200621748A (en) 2006-07-01
SV2007002219A (es) 2007-03-20
PA8643901A1 (es) 2006-05-16
AU2005282728A1 (en) 2006-03-16
EP1797068A1 (en) 2007-06-20
CN101080400A (zh) 2007-11-28
JP5701824B2 (ja) 2015-04-15
ES2437592T3 (es) 2014-01-13
BRPI0514865A (pt) 2008-06-24
EP2479172B1 (en) 2013-10-09
EP1797068B1 (en) 2013-10-09
ES2438725T3 (es) 2014-01-20
AR050724A1 (es) 2006-11-15
IL181674A0 (en) 2007-07-04
US20060052609A1 (en) 2006-03-09
KR20070057907A (ko) 2007-06-07
MX2007002521A (es) 2007-05-09
CA2579291A1 (en) 2006-03-16
UY29097A1 (es) 2006-03-31
EP2479172A1 (en) 2012-07-25
JP2012207040A (ja) 2012-10-25
CA2579291C (en) 2011-11-29
US7863451B2 (en) 2011-01-04
GT200500242A (es) 2006-06-22

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