SV2005001840A - Compuestos de oxazol para el tratamiento de trastornos neurodegenerativos - docket 17005 - Google Patents
Compuestos de oxazol para el tratamiento de trastornos neurodegenerativos - docket 17005Info
- Publication number
- SV2005001840A SV2005001840A SV2004001840A SV2004001840A SV2005001840A SV 2005001840 A SV2005001840 A SV 2005001840A SV 2004001840 A SV2004001840 A SV 2004001840A SV 2004001840 A SV2004001840 A SV 2004001840A SV 2005001840 A SV2005001840 A SV 2005001840A
- Authority
- SV
- El Salvador
- Prior art keywords
- compounds
- formula
- docket
- treatment
- neurodegenerative disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
COMPUESTOS DE FORMULA (VER FORMULA) EN DONDE R3, R5, R6, R7 Y Z, ASI COMO OTROS VALORES ENUMERADOS CON RELACION A R3, R5, R6, R7 Y Z SON COMO SE LOS DEFINE. LOS COMPUESTOS DE FORMULA I PRESENTAN ACTIVIDAD INHIBIDORA DE LA PRODUCCION DE PEPTIDO ABETA. ESTA INVENCION SE REFIERE ADEMAS A COMPOSICIONES FARMACEUTICAS Y METODOS PARA TRATAR ENFERMEDADES, POR EJEMPLO, ENFERMEDADES NEURODEGENERATIVAS, I.E. ENFERMEDAD DE ALZHEIMER, EN UN MAMIFERO, QUE COMPRENDEN COMPUESTOS DE FORMULA I.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49288403P | 2003-08-06 | 2003-08-06 | |
US49802803P | 2003-08-27 | 2003-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2005001840A true SV2005001840A (es) | 2005-11-04 |
Family
ID=34197958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2004001840A SV2005001840A (es) | 2003-08-06 | 2004-08-09 | Compuestos de oxazol para el tratamiento de trastornos neurodegenerativos - docket 17005 |
Country Status (13)
Country | Link |
---|---|
US (1) | US7112599B2 (es) |
EP (1) | EP1653952A4 (es) |
JP (1) | JP2007501244A (es) |
AR (1) | AR046327A1 (es) |
BR (1) | BRPI0413349A (es) |
CA (1) | CA2534529A1 (es) |
MX (1) | MXPA06001480A (es) |
PA (1) | PA8608601A1 (es) |
PE (1) | PE20050337A1 (es) |
SV (1) | SV2005001840A (es) |
TW (1) | TW200510351A (es) |
UY (1) | UY28458A1 (es) |
WO (1) | WO2005016267A2 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS50595B (sr) * | 2004-03-23 | 2010-05-07 | Pfizer Products Incorporated | Jedinjenja imidazola za lečenje neurodegenerativnih poremećaja |
US20050222227A1 (en) * | 2004-04-01 | 2005-10-06 | Pfizer Inc | Oxazole-amine compounds for the treatment of neurodegenerative disorders |
EP1940802A2 (en) * | 2005-09-22 | 2008-07-09 | Pfizer Products Inc. | Imidazole compounds for the treatment of neurological disorders |
KR101335845B1 (ko) | 2007-02-15 | 2013-12-02 | 에프. 호프만-라 로슈 아게 | Taar1 리간드로서의 2-아미노옥사졸린 |
DK2385938T3 (en) | 2009-01-12 | 2015-04-27 | Pfizer Ltd | Sulfonamidderivater |
EA201791271A1 (ru) * | 2012-05-31 | 2018-01-31 | Фенекс Фармасьютикалз Аг | ТИАЗОЛЫ, ЗАМЕЩЕННЫЕ КАРБОКСАМИДОМ ИЛИ СУЛЬФОНАМИДОМ, И РОДСТВЕННЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ МОДУЛЯТОРОВ ДЛЯ ОРФАННОГО ЯДЕРНОГО РЕЦЕПТОРА RORγ |
EP3768269A4 (en) * | 2018-03-23 | 2022-03-23 | Yumanity Therapeutics, Inc. | COMPOUNDS AND THEIR USES |
CN113651805B (zh) * | 2021-07-19 | 2023-07-25 | 安徽医科大学 | 一种1,2,4-噁二唑-吡啶类化合物及其在治疗阿尔茨海默症中的应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3094462A (en) * | 1961-09-18 | 1963-06-18 | Mcneilab Inc | Therapeutic reaction complex for muscle relaxation |
US3591584A (en) * | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
GB1264258A (es) * | 1970-10-10 | 1972-02-16 | ||
GB9320660D0 (en) * | 1993-10-07 | 1993-11-24 | British Bio Technology | Inhibition of cytokine production |
KR20000005291A (ko) * | 1996-06-25 | 2000-01-25 | 다케다 야쿠힌 고교 가부시키가이샤 | 옥사졸론 유도체 및 항-헬리코박터 파일로리 제제로서의 이의용도 |
US20020002199A1 (en) * | 1998-03-12 | 2002-01-03 | Lone Jeppesen | Modulators of protein tyrosine phosphatases (ptpases) |
WO2000059285A2 (en) * | 1999-04-02 | 2000-10-12 | Du Pont Pharmaceuticals Company | NOVEL LACTAM INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE |
TW593241B (en) * | 1999-04-20 | 2004-06-21 | Hoffmann La Roche | Carbamic acid derivatives |
AR039059A1 (es) * | 2001-08-06 | 2005-02-09 | Sanofi Aventis | Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios |
CN1688557A (zh) * | 2002-10-09 | 2005-10-26 | 辉瑞产品公司 | 用于治疗神经变性疾病的噻唑化合物 |
CA2501799C (en) * | 2002-10-09 | 2008-06-17 | Pfizer Products Inc. | Pyrazole compounds for treatment of neurodegenerative disorders |
AU2003298195B8 (en) * | 2002-12-23 | 2009-04-23 | F. Hoffmann-La Roche Ag | Oxazoles as mGluR1 enhancer |
PL378343A1 (pl) * | 2003-01-13 | 2006-03-20 | F. Hoffmann-La Roche Ag | Pochodne benzoksazolu i ich zastosowanie jako ligandów receptora adenozyny |
-
2004
- 2004-08-04 EP EP04779943A patent/EP1653952A4/en not_active Withdrawn
- 2004-08-04 WO PCT/US2004/025023 patent/WO2005016267A2/en active Application Filing
- 2004-08-04 JP JP2006522669A patent/JP2007501244A/ja not_active Withdrawn
- 2004-08-04 BR BRPI0413349-8A patent/BRPI0413349A/pt not_active IP Right Cessation
- 2004-08-04 CA CA002534529A patent/CA2534529A1/en not_active Abandoned
- 2004-08-04 MX MXPA06001480A patent/MXPA06001480A/es active IP Right Grant
- 2004-08-05 TW TW093123538A patent/TW200510351A/zh unknown
- 2004-08-05 US US10/911,869 patent/US7112599B2/en not_active Expired - Fee Related
- 2004-08-06 PA PA20048608601A patent/PA8608601A1/es unknown
- 2004-08-06 UY UY28458A patent/UY28458A1/es not_active Application Discontinuation
- 2004-08-06 PE PE2004000763A patent/PE20050337A1/es not_active Application Discontinuation
- 2004-08-06 AR ARP040102804A patent/AR046327A1/es unknown
- 2004-08-09 SV SV2004001840A patent/SV2005001840A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005016267A2 (en) | 2005-02-24 |
AR046327A1 (es) | 2005-12-07 |
PA8608601A1 (es) | 2005-03-03 |
PE20050337A1 (es) | 2005-06-06 |
JP2007501244A (ja) | 2007-01-25 |
CA2534529A1 (en) | 2005-02-24 |
MXPA06001480A (es) | 2006-05-15 |
EP1653952A4 (en) | 2007-04-04 |
BRPI0413349A (pt) | 2006-10-10 |
US20050032859A1 (en) | 2005-02-10 |
EP1653952A2 (en) | 2006-05-10 |
WO2005016267A3 (en) | 2005-04-21 |
UY28458A1 (es) | 2005-03-31 |
US7112599B2 (en) | 2006-09-26 |
TW200510351A (en) | 2005-03-16 |
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