BRPI0418181A - emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinson - Google Patents
emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinsonInfo
- Publication number
- BRPI0418181A BRPI0418181A BRPI0418181-6A BRPI0418181A BRPI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A
- Authority
- BR
- Brazil
- Prior art keywords
- substituted
- aminotetralines
- morbus parkinson
- prevent treatment
- parkinson
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
"EMPREGO DE 2-AMINOTETRALINAS SUBSTITUìDAS PARA PREVENçãO DO TRATAMENTO DE MORBUS PARKINSON". A presente invenção refere-se ao emprego de 2-aminotetralinas de fórmula geral (I) como medicamento para prevenção de Morbus Parkinson.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10361258A DE10361258A1 (de) | 2003-12-24 | 2003-12-24 | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
PCT/EP2004/014656 WO2005063238A1 (de) | 2003-12-24 | 2004-12-23 | Verwendung von substituierten 2-aminotetralinen zur vorbeugenden behandlung von morbus parkinson |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0418181A true BRPI0418181A (pt) | 2007-04-27 |
Family
ID=34706586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0418181-6A BRPI0418181A (pt) | 2003-12-24 | 2004-12-23 | emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinson |
Country Status (28)
Country | Link |
---|---|
US (1) | US8283376B2 (pt) |
EP (1) | EP1696905B1 (pt) |
JP (1) | JP5085938B2 (pt) |
KR (1) | KR20060125799A (pt) |
CN (1) | CN1897934B (pt) |
AT (1) | ATE389395T1 (pt) |
AU (1) | AU2004308649B2 (pt) |
BR (1) | BRPI0418181A (pt) |
CA (1) | CA2546797A1 (pt) |
CY (1) | CY1107956T1 (pt) |
DE (2) | DE10361258A1 (pt) |
DK (1) | DK1696905T3 (pt) |
EA (1) | EA011387B1 (pt) |
ES (1) | ES2303123T3 (pt) |
HK (1) | HK1094425A1 (pt) |
HR (1) | HRP20080175T3 (pt) |
IL (1) | IL175762A (pt) |
IS (1) | IS2517B (pt) |
MX (1) | MXPA06006693A (pt) |
NO (1) | NO20063275L (pt) |
NZ (1) | NZ547673A (pt) |
PL (1) | PL1696905T3 (pt) |
PT (1) | PT1696905E (pt) |
RS (1) | RS50578B (pt) |
SI (1) | SI1696905T1 (pt) |
UA (1) | UA83691C2 (pt) |
WO (1) | WO2005063238A1 (pt) |
ZA (1) | ZA200604114B (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10359528A1 (de) * | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
US8592477B2 (en) | 2007-11-28 | 2013-11-26 | Ucb Pharma Gmbh | Polymorphic form of rotigotine and process for production |
US8604242B2 (en) * | 2008-10-13 | 2013-12-10 | Interquim, S.A. | Process for the preparation of optically active (S)-(−)-2-(N-propylamino)-5-methoxytetraline and (S)-(−)-2-(N-propylamino)-5-hydroxytetraline compounds |
EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
WO2011033252A1 (en) * | 2009-09-16 | 2011-03-24 | United Arab Emirates University | Diagnostic agent for parkinson's disease |
KR20120107075A (ko) | 2009-10-16 | 2012-09-28 | 에파이오메드 테라퓨틱스, 아이엔씨. | 구토 치료 |
HUE039447T2 (hu) | 2009-12-22 | 2018-12-28 | Ucb Biopharma Sprl | Polivinilpirrolidon rotigotin nem kristályos formája szilárd diszperziójának stabilizálására |
US9956201B2 (en) | 2014-07-21 | 2018-05-01 | Spriaso Llc | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms |
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ES2203563T3 (es) | 2001-05-08 | 2004-04-16 | Schwarz Pharma Ag | Sistema terapeutico transdermico mejorado para el tratamiento de la enfermedad de parkinson. |
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DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10359528A1 (de) * | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
EP1547592A1 (en) * | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Intranasal formulation of rotigotine |
DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
CA2554616A1 (en) * | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and a dopamine agonist |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
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TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
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US8592477B2 (en) * | 2007-11-28 | 2013-11-26 | Ucb Pharma Gmbh | Polymorphic form of rotigotine and process for production |
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2003
- 2003-12-24 DE DE10361258A patent/DE10361258A1/de not_active Ceased
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2004
- 2004-12-23 AT AT04804250T patent/ATE389395T1/de active
- 2004-12-23 DK DK04804250T patent/DK1696905T3/da active
- 2004-12-23 DE DE502004006619T patent/DE502004006619D1/de active Active
- 2004-12-23 SI SI200430713T patent/SI1696905T1/sl unknown
- 2004-12-23 WO PCT/EP2004/014656 patent/WO2005063238A1/de active Application Filing
- 2004-12-23 US US10/585,609 patent/US8283376B2/en not_active Expired - Fee Related
- 2004-12-23 AU AU2004308649A patent/AU2004308649B2/en not_active Ceased
- 2004-12-23 PT PT04804250T patent/PT1696905E/pt unknown
- 2004-12-23 BR BRPI0418181-6A patent/BRPI0418181A/pt not_active IP Right Cessation
- 2004-12-23 PL PL04804250T patent/PL1696905T3/pl unknown
- 2004-12-23 CA CA002546797A patent/CA2546797A1/en not_active Abandoned
- 2004-12-23 EP EP04804250A patent/EP1696905B1/de active Active
- 2004-12-23 CN CN2004800384631A patent/CN1897934B/zh not_active Expired - Fee Related
- 2004-12-23 UA UAA200605754A patent/UA83691C2/ru unknown
- 2004-12-23 ES ES04804250T patent/ES2303123T3/es active Active
- 2004-12-23 NZ NZ547673A patent/NZ547673A/en not_active IP Right Cessation
- 2004-12-23 JP JP2006546072A patent/JP5085938B2/ja not_active Expired - Fee Related
- 2004-12-23 KR KR1020067011509A patent/KR20060125799A/ko not_active IP Right Cessation
- 2004-12-23 RS RSP-2008/0189A patent/RS50578B/sr unknown
- 2004-12-23 EA EA200600971A patent/EA011387B1/ru not_active IP Right Cessation
- 2004-12-23 MX MXPA06006693A patent/MXPA06006693A/es active IP Right Grant
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2006
- 2006-05-18 IL IL175762A patent/IL175762A/en not_active IP Right Cessation
- 2006-05-19 ZA ZA200604114A patent/ZA200604114B/xx unknown
- 2006-05-26 IS IS8485A patent/IS2517B/is unknown
- 2006-07-14 NO NO20063275A patent/NO20063275L/no not_active Application Discontinuation
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2007
- 2007-02-07 HK HK07101435A patent/HK1094425A1/xx not_active IP Right Cessation
-
2008
- 2008-04-16 HR HR20080175T patent/HRP20080175T3/xx unknown
- 2008-05-23 CY CY20081100530T patent/CY1107956T1/el unknown
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