HK55889A - 1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation - Google Patents

1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation

Info

Publication number
HK55889A
HK55889A HK558/89A HK55889A HK55889A HK 55889 A HK55889 A HK 55889A HK 558/89 A HK558/89 A HK 558/89A HK 55889 A HK55889 A HK 55889A HK 55889 A HK55889 A HK 55889A
Authority
HK
Hong Kong
Prior art keywords
cyclohexanyl
methyl
preparation
pyrrolidine derivatives
pyrrolidine
Prior art date
Application number
HK558/89A
Other languages
English (en)
Inventor
Michel Thominet
Jacqueline Franceschini
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7917610A external-priority patent/FR2460935A1/fr
Priority claimed from FR8007352A external-priority patent/FR2479218A2/fr
Application filed by Ile De France filed Critical Ile De France
Publication of HK55889A publication Critical patent/HK55889A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK558/89A 1979-07-06 1989-07-13 1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation HK55889A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7917610A FR2460935A1 (fr) 1979-07-06 1979-07-06 Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthetiques locaux
FR8007352A FR2479218A2 (fr) 1980-04-01 1980-04-01 Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthesiques locaux

Publications (1)

Publication Number Publication Date
HK55889A true HK55889A (en) 1989-07-21

Family

ID=26221244

Family Applications (2)

Application Number Title Priority Date Filing Date
HK556/89A HK55689A (en) 1979-07-06 1989-07-13 Substituted heterocyclic phenoxy amines,their preparation method and their use as local anaesthetics
HK558/89A HK55889A (en) 1979-07-06 1989-07-13 1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK556/89A HK55689A (en) 1979-07-06 1989-07-13 Substituted heterocyclic phenoxy amines,their preparation method and their use as local anaesthetics

Country Status (37)

Country Link
US (1) US4379161A (xx)
EP (2) EP0024960B1 (xx)
JP (2) JPS5639065A (xx)
AR (1) AR224012A1 (xx)
AT (2) ATE10739T1 (xx)
AU (2) AU536482B2 (xx)
BE (1) BE884124A (xx)
BG (2) BG35039A3 (xx)
CA (1) CA1163273A (xx)
CH (2) CH655100A5 (xx)
CS (1) CS216933B2 (xx)
DD (2) DD201141A5 (xx)
DE (2) DE3069789D1 (xx)
DK (1) DK157538C (xx)
ES (1) ES493111A0 (xx)
FI (2) FI74274C (xx)
GR (1) GR69638B (xx)
HK (2) HK55689A (xx)
HU (2) HU181147B (xx)
IE (2) IE50061B1 (xx)
IL (2) IL60472A (xx)
IN (2) IN153037B (xx)
IT (1) IT1188985B (xx)
JO (1) JO1077B1 (xx)
LU (1) LU82584A1 (xx)
MA (1) MA18893A1 (xx)
MX (2) MX6366E (xx)
NO (2) NO156086C (xx)
NZ (1) NZ194230A (xx)
OA (1) OA06561A (xx)
PH (1) PH16449A (xx)
PL (1) PL127393B1 (xx)
PT (1) PT71482A (xx)
RO (2) RO81532B (xx)
SU (1) SU1085507A3 (xx)
YU (2) YU42344B (xx)
ZW (1) ZW15280A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2586018B1 (fr) * 1985-08-12 1988-03-25 Ile De France Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique
WO1990012004A1 (en) * 1989-04-07 1990-10-18 Fujisawa Pharmaceutical Co., Ltd. New naphthalene compounds and method of producing the same
EP0471941A3 (en) * 1990-08-16 1992-10-14 American Cyanamid Company An improved process for the preparation of 5-bromo-2-methoxyresorcinol
US5472958A (en) * 1994-08-29 1995-12-05 Abbott Laboratories 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function
US7799337B2 (en) * 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
WO1999024422A1 (en) * 1997-11-05 1999-05-20 Neurosearch A/S Azaring-ether derivatives and their use as nicotinic ach receptor modulators
US8473062B2 (en) * 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) * 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US20100185249A1 (en) * 2009-01-22 2010-07-22 Wingeier Brett M Method and Devices for Adrenal Stimulation
CN111205015B (zh) * 2020-01-20 2021-11-26 东南大学 一种高稳定泡沫混凝土发泡剂的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE543876C (de) * 1928-04-25 1932-02-11 C H Boehringer Sohn Akt Ges Verfahren zur Darstellung von Piperidinalkinen
US3117976A (en) * 1958-11-12 1964-01-14 Beecham Res Lab Nu-alkyl-pyrrolidine-2-methanol, alpha cyclohexyl mandelates
FR1342756A (fr) * 1958-11-21 1963-11-15 Beecham Res Lab Esters basiques et leur procédé de préparation, notamment le phényl-cyclohexyl-glycolate de (1-méthyl-2-pyrrolidyl) méthyle et ses sels d'addition
GB1096441A (en) * 1964-01-15 1967-12-29 Bristol Myers Co Ethers of benzyl phenols and a process for the preparation thereof
US3904622A (en) * 1968-02-16 1975-09-09 Ile De France Dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene
GB1268951A (en) * 1969-06-12 1972-03-29 Pfizer Ltd Phenoxy-amines
FR2155927A1 (en) * 1971-10-15 1973-05-25 Synthelabo 1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity
JPS5139661A (en) * 1974-09-27 1976-04-02 Nippon Kayaku Kk Kogakukatsusei 11 mechiru 22 * beetaaa hidorokishechiru * pirorijin oyobisono chukantaino seizoho
JPS5251362A (en) * 1975-10-20 1977-04-25 Teijin Ltd Preparation of optically active pyrrolidine derivatives
LU78625A1 (de) * 1977-12-02 1979-06-13 Byk Gulden Lomberg Chem Fab Substituierte 1-phenyl-2-pyrrolidin-2-yl-ethanole,verfahren zu ihrer herstellung,ihre verwendung und sie enthaltende arzneimittel
DE2811952A1 (de) * 1978-03-18 1979-10-31 Merck Patent Gmbh Phenoxyalkylamine und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IL60472A (en) 1983-09-30
ATE17119T1 (de) 1986-01-15
SU1085507A3 (ru) 1984-04-07
NZ194230A (en) 1983-02-15
IL68854A0 (en) 1983-10-31
MX6366E (es) 1985-05-21
IE50061B1 (en) 1986-02-05
AU563009B2 (en) 1987-06-25
MX7642E (es) 1990-05-16
CA1163273A (fr) 1984-03-06
RO85323B (ro) 1984-10-30
IT8049163A1 (it) 1982-01-04
HU181147B (en) 1983-06-28
PT71482A (fr) 1980-08-01
RO81532A (ro) 1983-04-29
NO861988L (no) 1981-01-07
AU536482B2 (en) 1984-05-10
DE3071314D1 (en) 1986-02-06
EP0024960B1 (fr) 1984-12-12
DK157538B (da) 1990-01-22
JPH0149704B2 (xx) 1989-10-25
PH16449A (en) 1983-10-12
GR69638B (xx) 1982-07-06
MA18893A1 (fr) 1981-04-01
RO81532B (ro) 1983-04-30
FI872955A (fi) 1987-07-03
IT1188985B (it) 1988-01-28
PL225473A1 (xx) 1981-10-16
AU6002880A (en) 1981-01-15
DD201141A5 (de) 1983-07-06
IN153037B (xx) 1984-05-26
FI74274B (fi) 1987-09-30
JO1077B1 (en) 1982-07-10
BG35746A3 (en) 1984-06-15
DE3069789D1 (en) 1985-01-24
JPS5649351A (en) 1981-05-02
IE801392L (en) 1981-01-06
YU42824B (en) 1988-12-31
FI872955A0 (fi) 1987-07-03
YU171080A (en) 1983-06-30
CS216933B2 (en) 1982-12-31
EP0024960A2 (fr) 1981-03-11
JPS5639065A (en) 1981-04-14
CH655100A5 (fr) 1986-03-27
ES8103049A1 (es) 1981-02-16
FI802156A (fi) 1981-01-07
OA06561A (fr) 1981-07-31
RO85323A (ro) 1984-09-29
FI74274C (fi) 1988-01-11
HK55689A (en) 1989-07-21
NO802027L (no) 1981-01-07
DK157538C (da) 1990-06-11
IL60472A0 (en) 1980-09-16
US4379161A (en) 1983-04-05
EP0094102A2 (fr) 1983-11-16
IE801390L (en) 1981-01-04
JPH0122264B2 (xx) 1989-04-25
EP0094102A3 (en) 1984-04-11
EP0094102B1 (fr) 1985-12-27
EP0024960A3 (en) 1981-06-17
IT8049163A0 (it) 1980-07-04
ATE10739T1 (de) 1984-12-15
AU2526084A (en) 1984-07-26
YU42344B (en) 1988-08-31
PL127393B1 (en) 1983-10-31
IE50060B1 (en) 1986-02-05
BE884124A (fr) 1981-01-05
AR224012A1 (es) 1981-10-15
NO156086B (no) 1987-04-13
LU82584A1 (fr) 1981-02-02
BG35039A3 (en) 1984-01-16
DD153206A5 (de) 1981-12-30
IN158706B (xx) 1987-01-10
DK289580A (da) 1981-01-07
YU280182A (en) 1983-06-30
ZW15280A1 (en) 1980-10-01
CH648827A5 (fr) 1985-04-15
NO156086C (no) 1987-07-22
ES493111A0 (es) 1981-02-16
HU186539B (en) 1985-08-28

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