HK55689A - Substituted heterocyclic phenoxy amines,their preparation method and their use as local anaesthetics - Google Patents
Substituted heterocyclic phenoxy amines,their preparation method and their use as local anaestheticsInfo
- Publication number
- HK55689A HK55689A HK556/89A HK55689A HK55689A HK 55689 A HK55689 A HK 55689A HK 556/89 A HK556/89 A HK 556/89A HK 55689 A HK55689 A HK 55689A HK 55689 A HK55689 A HK 55689A
- Authority
- HK
- Hong Kong
- Prior art keywords
- amines
- preparation
- substituted heterocyclic
- local anaesthetics
- phenoxy
- Prior art date
Links
- -1 heterocyclic phenoxy amines Chemical class 0.000 title 1
- 229960005015 local anesthetics Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7917610A FR2460935A1 (fr) | 1979-07-06 | 1979-07-06 | Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthetiques locaux |
| FR8007352A FR2479218A2 (fr) | 1980-04-01 | 1980-04-01 | Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthesiques locaux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK55689A true HK55689A (en) | 1989-07-21 |
Family
ID=26221244
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK558/89A HK55889A (en) | 1979-07-06 | 1989-07-13 | 1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation |
| HK556/89A HK55689A (en) | 1979-07-06 | 1989-07-13 | Substituted heterocyclic phenoxy amines,their preparation method and their use as local anaesthetics |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK558/89A HK55889A (en) | 1979-07-06 | 1989-07-13 | 1-(1-cyclohexanyl-methyl)pyrrolidine derivatives,and process for their preparation |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US4379161A (ro) |
| EP (2) | EP0024960B1 (ro) |
| JP (2) | JPS5639065A (ro) |
| AR (1) | AR224012A1 (ro) |
| AT (2) | ATE17119T1 (ro) |
| AU (2) | AU536482B2 (ro) |
| BE (1) | BE884124A (ro) |
| BG (2) | BG35039A3 (ro) |
| CA (1) | CA1163273A (ro) |
| CH (2) | CH648827A5 (ro) |
| CS (1) | CS216933B2 (ro) |
| DD (2) | DD201141A5 (ro) |
| DE (2) | DE3071314D1 (ro) |
| DK (1) | DK157538C (ro) |
| ES (1) | ES493111A0 (ro) |
| FI (2) | FI74274C (ro) |
| GR (1) | GR69638B (ro) |
| HK (2) | HK55889A (ro) |
| HU (2) | HU181147B (ro) |
| IE (2) | IE50061B1 (ro) |
| IL (2) | IL60472A (ro) |
| IN (2) | IN153037B (ro) |
| IT (1) | IT1188985B (ro) |
| JO (1) | JO1077B1 (ro) |
| LU (1) | LU82584A1 (ro) |
| MA (1) | MA18893A1 (ro) |
| MX (2) | MX7642E (ro) |
| NO (2) | NO156086C (ro) |
| NZ (1) | NZ194230A (ro) |
| OA (1) | OA06561A (ro) |
| PH (1) | PH16449A (ro) |
| PL (1) | PL127393B1 (ro) |
| PT (1) | PT71482A (ro) |
| RO (2) | RO85323B (ro) |
| SU (1) | SU1085507A3 (ro) |
| YU (2) | YU42344B (ro) |
| ZW (1) | ZW15280A1 (ro) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586018B1 (fr) * | 1985-08-12 | 1988-03-25 | Ile De France | Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique |
| WO1990012004A1 (en) * | 1989-04-07 | 1990-10-18 | Fujisawa Pharmaceutical Co., Ltd. | New naphthalene compounds and method of producing the same |
| EP0471941A3 (en) * | 1990-08-16 | 1992-10-14 | American Cyanamid Company | An improved process for the preparation of 5-bromo-2-methoxyresorcinol |
| US5472958A (en) * | 1994-08-29 | 1995-12-05 | Abbott Laboratories | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function |
| US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
| CA2306477A1 (en) * | 1997-11-05 | 1999-05-20 | Neurosearch A/S | Azaring-ether derivatives and their use as nicotinic ach receptor modulators |
| US8473062B2 (en) * | 2008-05-01 | 2013-06-25 | Autonomic Technologies, Inc. | Method and device for the treatment of headache |
| US8412336B2 (en) | 2008-12-29 | 2013-04-02 | Autonomic Technologies, Inc. | Integrated delivery and visualization tool for a neuromodulation system |
| US9320908B2 (en) * | 2009-01-15 | 2016-04-26 | Autonomic Technologies, Inc. | Approval per use implanted neurostimulator |
| US8494641B2 (en) | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
| US20100185249A1 (en) * | 2009-01-22 | 2010-07-22 | Wingeier Brett M | Method and Devices for Adrenal Stimulation |
| CN111205015B (zh) * | 2020-01-20 | 2021-11-26 | 东南大学 | 一种高稳定泡沫混凝土发泡剂的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE543876C (de) * | 1928-04-25 | 1932-02-11 | C H Boehringer Sohn Akt Ges | Verfahren zur Darstellung von Piperidinalkinen |
| US3117976A (en) * | 1958-11-12 | 1964-01-14 | Beecham Res Lab | Nu-alkyl-pyrrolidine-2-methanol, alpha cyclohexyl mandelates |
| FR1342756A (fr) * | 1958-11-21 | 1963-11-15 | Beecham Res Lab | Esters basiques et leur procédé de préparation, notamment le phényl-cyclohexyl-glycolate de (1-méthyl-2-pyrrolidyl) méthyle et ses sels d'addition |
| GB1096441A (en) * | 1964-01-15 | 1967-12-29 | Bristol Myers Co | Ethers of benzyl phenols and a process for the preparation thereof |
| US3904622A (en) * | 1968-02-16 | 1975-09-09 | Ile De France | Dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene |
| GB1268951A (en) * | 1969-06-12 | 1972-03-29 | Pfizer Ltd | Phenoxy-amines |
| FR2155927A1 (en) * | 1971-10-15 | 1973-05-25 | Synthelabo | 1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity |
| JPS5139661A (en) * | 1974-09-27 | 1976-04-02 | Nippon Kayaku Kk | Kogakukatsusei 11 mechiru 22 * beetaaa hidorokishechiru * pirorijin oyobisono chukantaino seizoho |
| JPS5251362A (en) * | 1975-10-20 | 1977-04-25 | Teijin Ltd | Preparation of optically active pyrrolidine derivatives |
| LU78625A1 (de) * | 1977-12-02 | 1979-06-13 | Byk Gulden Lomberg Chem Fab | Substituierte 1-phenyl-2-pyrrolidin-2-yl-ethanole,verfahren zu ihrer herstellung,ihre verwendung und sie enthaltende arzneimittel |
| DE2811952A1 (de) * | 1978-03-18 | 1979-10-31 | Merck Patent Gmbh | Phenoxyalkylamine und verfahren zu ihrer herstellung |
-
1980
- 1980-06-25 US US06/162,796 patent/US4379161A/en not_active Expired - Lifetime
- 1980-07-01 EP EP80400999A patent/EP0024960B1/fr not_active Expired
- 1980-07-01 OA OA57149A patent/OA06561A/xx unknown
- 1980-07-01 BG BG048341A patent/BG35039A3/xx unknown
- 1980-07-01 EP EP83105420A patent/EP0094102B1/fr not_active Expired
- 1980-07-01 AT AT83105420T patent/ATE17119T1/de not_active IP Right Cessation
- 1980-07-01 AT AT80400999T patent/ATE10739T1/de not_active IP Right Cessation
- 1980-07-01 BG BG062115A patent/BG35746A3/xx unknown
- 1980-07-01 YU YU1710/80A patent/YU42344B/xx unknown
- 1980-07-01 DE DE8383105420T patent/DE3071314D1/de not_active Expired
- 1980-07-01 SU SU802938255A patent/SU1085507A3/ru active
- 1980-07-01 CS CS804693A patent/CS216933B2/cs unknown
- 1980-07-01 DE DE8080400999T patent/DE3069789D1/de not_active Expired
- 1980-07-02 IL IL60472A patent/IL60472A/xx unknown
- 1980-07-02 PT PT71482A patent/PT71482A/pt unknown
- 1980-07-02 BE BE1/9873A patent/BE884124A/fr not_active IP Right Cessation
- 1980-07-02 AU AU60028/80A patent/AU536482B2/en not_active Ceased
- 1980-07-03 AR AR281635A patent/AR224012A1/es active
- 1980-07-03 HU HU80801658A patent/HU181147B/hu not_active IP Right Cessation
- 1980-07-03 NZ NZ194230A patent/NZ194230A/xx unknown
- 1980-07-03 RO RO110029A patent/RO85323B/ro unknown
- 1980-07-03 HU HU822217A patent/HU186539B/hu not_active IP Right Cessation
- 1980-07-03 RO RO101590A patent/RO81532B/ro unknown
- 1980-07-04 NO NO802027A patent/NO156086C/no unknown
- 1980-07-04 GR GR62381A patent/GR69638B/el unknown
- 1980-07-04 MX MX8011334U patent/MX7642E/es unknown
- 1980-07-04 ES ES493111A patent/ES493111A0/es active Granted
- 1980-07-04 FI FI802156A patent/FI74274C/fi not_active IP Right Cessation
- 1980-07-04 CH CH5169/80A patent/CH648827A5/fr not_active IP Right Cessation
- 1980-07-04 IE IE1653/85A patent/IE50061B1/en not_active IP Right Cessation
- 1980-07-04 MA MA19091A patent/MA18893A1/fr unknown
- 1980-07-04 CH CH5684/84A patent/CH655100A5/fr not_active IP Right Cessation
- 1980-07-04 DK DK289580A patent/DK157538C/da not_active IP Right Cessation
- 1980-07-04 PL PL1980225473A patent/PL127393B1/pl unknown
- 1980-07-04 MX MX80100439U patent/MX6366E/es unknown
- 1980-07-04 IT IT49163/80A patent/IT1188985B/it active
- 1980-07-04 LU LU82584A patent/LU82584A1/fr unknown
- 1980-07-04 IE IE1392/80A patent/IE50060B1/en not_active IP Right Cessation
- 1980-07-04 ZW ZW152/80A patent/ZW15280A1/xx unknown
- 1980-07-05 JO JO19801077A patent/JO1077B1/en active
- 1980-07-05 IN IN779/CAL/80A patent/IN153037B/en unknown
- 1980-07-07 JP JP9321680A patent/JPS5639065A/ja active Granted
- 1980-07-07 DD DD80234984A patent/DD201141A5/de not_active IP Right Cessation
- 1980-07-07 PH PH24248A patent/PH16449A/en unknown
- 1980-07-07 DD DD222455A patent/DD153206A5/de unknown
- 1980-09-30 JP JP13751280A patent/JPS5649351A/ja active Granted
-
1982
- 1982-12-16 CA CA000417963A patent/CA1163273A/fr not_active Expired
- 1982-12-17 YU YU2801/82A patent/YU42824B/xx unknown
-
1983
- 1983-06-01 IL IL68854A patent/IL68854A0/xx not_active IP Right Cessation
- 1983-10-10 IN IN1246/CAL/83A patent/IN158706B/en unknown
-
1984
- 1984-03-02 AU AU25260/84A patent/AU563009B2/en not_active Ceased
-
1986
- 1986-05-20 NO NO861988A patent/NO861988L/no unknown
-
1987
- 1987-07-03 FI FI872955A patent/FI872955A/fi not_active Application Discontinuation
-
1989
- 1989-07-13 HK HK558/89A patent/HK55889A/xx unknown
- 1989-07-13 HK HK556/89A patent/HK55689A/xx unknown
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