HK52391A - (s)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide - Google Patents

(s)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide

Info

Publication number
HK52391A
HK52391A HK523/91A HK52391A HK52391A HK 52391 A HK52391 A HK 52391A HK 523/91 A HK523/91 A HK 523/91A HK 52391 A HK52391 A HK 52391A HK 52391 A HK52391 A HK 52391A
Authority
HK
Hong Kong
Prior art keywords
radical
oxo
alpha
ethyl
pyrrolidinacetamide
Prior art date
Application number
HK523/91A
Other languages
English (en)
Inventor
Jean Gobert
Jean-Pierre Geerts
Guy Bodson
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10560974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK52391(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of HK52391A publication Critical patent/HK52391A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Detergent Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
HK523/91A 1984-05-15 1991-07-11 (s)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide HK52391A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848412357A GB8412357D0 (en) 1984-05-15 1984-05-15 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
HK52391A true HK52391A (en) 1991-07-19

Family

ID=10560974

Family Applications (1)

Application Number Title Priority Date Filing Date
HK523/91A HK52391A (en) 1984-05-15 1991-07-11 (s)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide

Country Status (33)

Country Link
US (3) US4696943A (sv)
EP (1) EP0162036B1 (sv)
JP (1) JPH0629186B2 (sv)
KR (1) KR920003819B1 (sv)
CN (1) CN1015541B (sv)
AT (1) ATE45567T1 (sv)
AU (1) AU574465B2 (sv)
BG (2) BG50156A3 (sv)
CA (1) CA1235129A (sv)
CY (2) CY1567A (sv)
DE (3) DE10199005I2 (sv)
DK (1) DK163501C (sv)
ES (2) ES8608485A1 (sv)
FI (1) FI80673C (sv)
GB (1) GB8412357D0 (sv)
GE (1) GEP20002001B (sv)
GR (1) GR851155B (sv)
HK (1) HK52391A (sv)
IE (1) IE59950B1 (sv)
IL (1) IL75179A (sv)
LT (1) LT2584B (sv)
LU (2) LU90615I2 (sv)
LV (1) LV5233A3 (sv)
MY (2) MY101726A (sv)
NL (1) NL300028I2 (sv)
NO (2) NO164534C (sv)
PL (2) PL144346B1 (sv)
PT (1) PT80460B (sv)
SA (1) SA01210656A (sv)
SG (1) SG80090G (sv)
SU (3) SU1402260A3 (sv)
UA (1) UA6158A1 (sv)
ZA (1) ZA853635B (sv)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827389D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide
IT1231477B (it) * 1989-07-12 1991-12-07 Sigma Tau Ind Farmaceuti (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
GB9319732D0 (en) 1993-09-24 1993-11-10 Ucb Sa Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
US6124473A (en) * 1998-05-08 2000-09-26 Ucb, S.A. Process for preparing (s)- and (R)-α-ethyl-2-oxo-1-pyrrolidineacetamide
US6107492A (en) * 1998-05-08 2000-08-22 Ucb, S.A. Process for the preparation of levetiracetam
EA002380B1 (ru) * 1999-07-21 2002-04-25 Российский Государственный Педагогический Университет Им. А.И.Герцена Антиишемическое средство
EA002379B1 (ru) * 1999-07-21 2002-04-25 Российский Государственный Педагогический Университет Им. А.И.Герцена Средство, обладающее антиишемической, гипотензивной и антигипоксической активностью
DE60034815T2 (de) * 1999-12-01 2008-01-31 Ucb S.A. Ein pyrrolidinacetatderivat zur behandlung von chronischem oder neuropathischem schmerz
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
US6686477B2 (en) * 2000-09-29 2004-02-03 Eastman Chemical Company Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same
DE60134337D1 (de) * 2000-11-21 2008-07-17 Ucb Pharma Sa N-alkylierte gaba verbindungen, verfahren zu deren
WO2002053153A1 (fr) 2000-12-28 2002-07-11 Daiichi Pharmaceutical Co., Ltd. Medicaments permettant de traiter et de prevenir une douleur neurologique
CA2438930A1 (en) * 2001-02-23 2002-09-06 Johns Hopkins University Treatment of tics, tremors and related disorders
IL160045A0 (en) 2001-08-10 2004-06-20 Ucb Sa Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
PL370529A1 (en) * 2001-10-08 2005-05-30 Ucb, S.A. Use of 2-oxo-1-pyrrolidine derivatives for the preparation of a drug
AU2003242538A1 (en) * 2002-05-14 2003-11-11 Ucb, S.A. Use of 2-oxo-1-pyrrolidone derivatives for the preparation of a drug
CA2515090A1 (en) * 2003-02-03 2004-08-19 Teva Pharmaceutical Industries Ltd Process for producing levetiracetam
ES2214147B1 (es) 2003-02-28 2005-10-01 Farma-Lepori S.A. Procedimiento de obtencion de un agente antiepileptico.
US20050143445A1 (en) * 2003-03-18 2005-06-30 Parthasaradhi Reddy B. Novel crystalline forms of levetiracetam
WO2005023763A1 (en) * 2003-09-05 2005-03-17 Ranbaxy Laboratories Limited Process for the preparation of pure levetiracetam
PL1667967T3 (pl) * 2003-09-24 2012-11-30 Ucb Pharma Sa Sposób wytwarzania pochodnych 2-okso-1-pirolidyny
EP2050736A1 (en) 2003-12-02 2009-04-22 UCB Pharma, S.A. Imidazole derivatives, processes for preparing them and their uses
CA2497062A1 (en) 2004-02-18 2005-08-18 Dr. Reddy's Laboratories Limited Preparation of amino acid amides
CA2488325C (en) * 2004-11-22 2010-08-24 Apotex Pharmachem Inc. Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide
ES2294979T1 (es) * 2005-01-27 2008-04-16 Alembic Limited Formulacion de levetiracetam de liberacion prolongada.
WO2006088864A1 (en) * 2005-02-16 2006-08-24 Elan Pharma International Limited Controlled release compositions comprising levetiracetam
US20070298098A1 (en) * 2005-02-16 2007-12-27 Elan Pharma International Limited Controlled Release Compositions Comprising Levetiracetam
WO2006090265A2 (en) * 2005-02-28 2006-08-31 Ranbaxy Laboratories Limited Processes for the preparation of levetiracetam, its intermediate and the use of levetiracetam in pharmaceutical compositions
WO2006095362A1 (en) * 2005-03-10 2006-09-14 Rubamin Limited Process for preparing levetiracetam
AU2006228947A1 (en) * 2005-03-30 2006-10-05 Mylan Pharmaceuticals Ulc Combined-step process for pharmaceutical compositions
WO2006103696A2 (en) * 2005-04-01 2006-10-05 Rubamin Laboratories Limited Process for preparing levetiracetam and racemization of (r)- and (s)-2-amino butynamide and the corresponding acid derivatives
AU2006254335A1 (en) 2005-06-01 2006-12-07 Ucb Pharma, S.A. 2-oxo-1-pyrrolidine derivatives and their therapeutic use on the central nervous system
US8802142B2 (en) 2005-07-26 2014-08-12 Ucb Pharma, S.A. Pharmaceutical compositions comprising levetiracetam and process for their preparation
US8338621B2 (en) 2005-12-21 2012-12-25 Ucb S.A. Process for the preparation of 2-oxo-1-pyrrolidine derivatives
ATE413875T1 (de) * 2006-01-24 2008-11-15 Teva Pharma Zusammensetzungen enthaltend levetiracetam und verfahren zu deren herstellung.
US20080014271A1 (en) * 2006-07-13 2008-01-17 Ucb, S.A. Novel pharmaceutical compositions comprising levetiracetam
EP2049476A1 (en) * 2006-07-25 2009-04-22 ZaCh System S.p.A. Process for the preparation of levetiracetam
EP2051696A2 (en) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
CN101130504B (zh) * 2006-08-25 2010-07-28 苏州雅本化学股份有限公司 经合成、拆分与消旋化制备手性药物左乙拉西坦中间体(s)-(+)-2-氨基丁酰胺盐酸盐的方法
EP1932922A1 (de) * 2006-12-13 2008-06-18 Desitin Arzneimittel GmbH Schnelltest zum Nachweis von DNA-Sequenzen
WO2008077035A2 (en) * 2006-12-18 2008-06-26 Dr. Reddy's Laboratories Ltd. Processes for the preparation of levetiracetam
CN101333180B (zh) * 2007-06-29 2011-05-18 浙江华海药业股份有限公司 一种制备左乙拉西坦中间体的方法
US20090082422A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched levetiracetam
WO2009050735A1 (en) * 2007-10-15 2009-04-23 Lupin Limited A novel polymorph of levetiracetam and a process for its preparation
US20090263481A1 (en) * 2008-04-17 2009-10-22 Atul Vishvanath Patil Levetiracetam formulations
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
EP2147911A1 (en) 2008-07-24 2010-01-27 ZaCh System S.p.A. Process for the preparation of levetiracetam
US20100190752A1 (en) * 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
DK3260118T3 (da) * 2008-10-16 2021-04-19 Univ Johns Hopkins Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion
EP2179725A1 (en) 2008-10-23 2010-04-28 LEK Pharmaceuticals D.D. Pharmaceutical composition comprising levetiracetam
US8722715B2 (en) * 2008-11-07 2014-05-13 NovaBay Pharmaceuticals Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
US20100172979A1 (en) * 2008-12-24 2010-07-08 Zhongshui Yu Controlled-release formulations
US20100159009A1 (en) * 2008-12-24 2010-06-24 Zhongshui Yu Controlled-release formulations
WO2010132693A2 (en) 2009-05-13 2010-11-18 Nektar Therapeutics Oligomer-containing pyrrolidine compounds
CN101885696A (zh) * 2009-05-14 2010-11-17 上海华理生物医药有限公司 一种合成高纯度左乙拉西坦的方法
EP2461808A2 (en) 2009-08-07 2012-06-13 UCB Pharma S.A. Methods for enhancing the cognitive function
EP2298290A1 (en) 2009-09-16 2011-03-23 LEK Pharmaceuticals d.d. Controlled release composition comprising levetiracetam
US7939676B2 (en) * 2009-09-17 2011-05-10 Zach System S.P.A. Process for the preparation of levetiracetam
BR112012009310B8 (pt) 2009-10-23 2021-05-25 Ucb Biopharma Sprl composto derivados de 2-oxo-1-pirrolidinil imidazotiadiazol, uso dos mesmos e composição farmacêutica compreendendo os mesmos
JP6082250B2 (ja) * 2010-02-09 2017-02-15 ザ・ジョンズ・ホプキンス・ユニバーシティー 認知機能を改善するための方法および組成物
WO2011106696A2 (en) 2010-02-26 2011-09-01 The Regents Of The University Of California Compositions and methods for the production of l-homoalanine
EP2563340A2 (en) 2010-04-26 2013-03-06 Mahmut Bilgic Water soluble pharmaceutical composition
US9333175B2 (en) 2010-06-16 2016-05-10 Mylan Inc. Controlled release levetiracetam formulations and methods for producing the same
EP2492354A1 (en) 2011-02-23 2012-08-29 Institut National De La Recherche Agronomique (INRA) Method for identifying compounds useful in the treatment of photosensitive reflex epilepsy
PT2699581E (pt) 2011-04-18 2016-03-22 Ucb Biopharma Sprl Derivados de 2-oxo-1-imidazolidinil-imidazotiazole
EP2524910A1 (en) 2011-05-17 2012-11-21 DSM IP Assets B.V. Process for the resolution of aminobutyramide
CN102382027B (zh) * 2011-09-20 2013-11-13 浙江江北药业有限公司 一种左乙拉西坦的制备方法
CN102617436B (zh) * 2012-03-20 2014-02-12 浙江洪波化工有限公司 2-(2-氧代吡咯烷基）丁酰胺的制备方法
CN102633675A (zh) * 2012-04-10 2012-08-15 南京大学 一种dl-2-氨基丁酰胺制备方法
CN102675181B (zh) * 2012-06-07 2013-11-20 北京师宏药物研制中心 一种左乙拉西坦的制备方法
CN102702063B (zh) * 2012-06-15 2013-09-04 孙威 一种左乙拉西坦制备方法
WO2014012563A1 (en) 2012-07-20 2014-01-23 Ucb Pharma, S.A. Compounds for enhancing the cognitive function
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN103012190B (zh) * 2012-12-05 2015-03-18 江苏拜克新材料有限公司 一种s-2-氨基丁酰胺盐酸盐的合成方法
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
JP6170234B2 (ja) 2013-03-15 2017-07-26 アプレシア・ファーマスーティカルズ・カンパニー レベチラセタムを含む急速に分散する剤形
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
KR102502485B1 (ko) 2014-01-21 2023-02-21 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
CN103922988A (zh) * 2014-04-29 2014-07-16 苏州天马精细化学品股份有限公司 一种左乙拉西坦粗品的纯化方法
CN103910649A (zh) * 2014-04-29 2014-07-09 苏州天马精细化学品股份有限公司 一种左乙拉西坦中间体（s）-n-[1-(氨基羰基)丙基]-4-氯代丁酰胺的合成方法
CN104860863B (zh) * 2015-04-10 2017-06-20 惠州信立泰药业有限公司 左乙拉西坦和含其的药物组合物
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam
AU2016381366A1 (en) 2015-12-30 2018-06-28 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of seizure-related disorders
CN106432032B (zh) * 2016-09-14 2019-07-12 苏州天马药业有限公司 一种左乙拉西坦的制备方法
CN106591179B (zh) * 2016-12-05 2018-07-03 长兴制药股份有限公司 甲基包囊菌及其在选择性拆分制备(S)-α-乙基-2-氧-1-吡咯烷乙酸盐上的应用
US11213517B2 (en) 2016-12-16 2022-01-04 Idorsia Pharmaceuticals Ltd Pharmaceutical combination comprising a T-type calcium channel blocker
CN108503610B (zh) 2017-02-24 2019-09-13 北京艾百诺医药股份有限公司 一种光学纯的(r)-4-正丙基-二氢呋喃-2(3h)-酮的制备方法
CN107337628B (zh) 2017-08-10 2022-02-08 浙江华海药业股份有限公司 一种制备左乙拉西坦的方法
TWI826531B (zh) 2018-09-21 2023-12-21 南韓商愛思開生物製藥股份有限公司 具有㗁二唑之化合物及包含該化合物之醫藥組合物
CN110003074A (zh) 2019-04-23 2019-07-12 浙江华海药业股份有限公司 一种左乙拉西坦中间体的制备方法
TW202114655A (zh) 2019-08-14 2021-04-16 瑞士商辛鐵堤卡公司 左乙拉西坦(levetiracetam)之鞘內投藥
US11384050B1 (en) 2021-02-03 2022-07-12 Vitaworks Ip, Llc Method for preparing levetiracetam and intermediates thereof
EP4297749A1 (en) 2021-02-26 2024-01-03 Syndesi Therapeutics SA Compound for treatment of cognitive disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309692A (en) * 1970-02-13 1973-03-14 Ucb Sa N-substituted lactams
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
FR2418790A1 (fr) * 1978-03-02 1979-09-28 Philagro Sa Nouveaux derives de pyrrolidinone-2 et compositions herbicides les contenant
GB8412358D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition

Also Published As

Publication number Publication date
IE851193L (en) 1985-11-15
KR850008336A (ko) 1985-12-16
CY1567A (en) 1991-12-20
GR851155B (sv) 1985-11-25
NL300028I2 (nl) 2001-06-01
IE59950B1 (en) 1994-05-04
FI80673B (fi) 1990-03-30
US4837223A (en) 1989-06-06
PL147386B1 (en) 1989-05-31
CA1235129A (en) 1988-04-12
JPS60252461A (ja) 1985-12-13
SU1428195A3 (ru) 1988-09-30
SU1402260A3 (ru) 1988-06-07
ATE45567T1 (de) 1989-09-15
GB8412357D0 (en) 1984-06-20
US4696943A (en) 1987-09-29
DE10075021I1 (de) 2000-10-19
DE3572348D1 (de) 1989-09-21
ZA853635B (en) 1985-12-24
NO2001008I2 (no) 2005-05-30
ES8608485A1 (es) 1986-06-16
CN1015541B (zh) 1992-02-19
EP0162036B1 (fr) 1989-08-16
IL75179A0 (en) 1985-09-29
MY101725A (en) 1992-01-17
BG50156A3 (en) 1992-05-15
PT80460A (fr) 1985-06-01
AU4253085A (en) 1986-11-20
SG80090G (en) 1990-11-23
IL75179A (en) 1988-05-31
DK163501B (da) 1992-03-09
AU574465B2 (en) 1988-07-07
GEP20002001B (en) 2000-03-10
SU1430392A1 (ru) 1988-10-15
LT2584B (lt) 1994-03-25
LU90682I2 (fr) 2001-01-30
ES8704893A1 (es) 1987-04-16
PL144346B1 (en) 1988-05-31
SA01210656A (ar) 2005-12-03
ES543124A0 (es) 1986-06-16
NO164534C (no) 1990-10-17
BG47497A3 (en) 1990-07-16
PT80460B (pt) 1987-08-19
PL253374A1 (en) 1986-05-06
MY101726A (en) 1992-01-17
LV5233A3 (lv) 1993-10-10
CN85105301A (zh) 1987-01-14
DK212985A (da) 1985-11-16
PL257385A1 (en) 1986-10-07
EP0162036A1 (fr) 1985-11-21
CY2004007I1 (el) 2009-11-04
NO164534B (no) 1990-07-09
DE10199005I2 (de) 2002-03-14
UA6158A1 (uk) 1994-12-29
DE10199005I1 (de) 2001-07-12
DK163501C (da) 1992-07-27
FI851875A0 (fi) 1985-05-13
FI851875L (fi) 1985-11-16
CY2004007I2 (el) 2009-11-04
US4943639A (en) 1990-07-24
JPH0629186B2 (ja) 1994-04-20
KR920003819B1 (ko) 1992-05-15
ES8704893B9 (es) 2012-02-07
LU90615I2 (fr) 2000-10-02
DK212985D0 (da) 1985-05-14
NL300028I1 (nl) 2001-02-01
FI80673C (sv) 1990-07-10
NO851933L (no) 1985-11-18

Similar Documents

Publication Publication Date Title
AU574465B2 (en) (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide
AU574175B2 (en) (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20050513