HK49496A - Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof - Google Patents

Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof

Info

Publication number
HK49496A
HK49496A HK49496A HK49496A HK49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A
Authority
HK
Hong Kong
Prior art keywords
enoic
hept
derivatives
substituted
preparation
Prior art date
Application number
HK49496A
Other languages
English (en)
Inventor
Kau-Ming Chen
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26945992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK49496(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK49496A publication Critical patent/HK49496A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK49496A 1988-10-13 1996-03-21 Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof HK49496A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25747588A 1988-10-13 1988-10-13
US35553189A 1989-05-22 1989-05-22

Publications (1)

Publication Number Publication Date
HK49496A true HK49496A (en) 1996-03-29

Family

ID=26945992

Family Applications (1)

Application Number Title Priority Date Filing Date
HK49496A HK49496A (en) 1988-10-13 1996-03-21 Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof

Country Status (24)

Country Link
EP (2) EP0363934B1 (xx)
JP (1) JP2853227B2 (xx)
KR (1) KR0162656B1 (xx)
AT (1) ATE99281T1 (xx)
AU (1) AU636122B2 (xx)
BG (1) BG60555B1 (xx)
CA (1) CA2000553C (xx)
CZ (1) CZ283316B6 (xx)
DE (1) DE68911834T2 (xx)
DK (1) DK175073B1 (xx)
ES (1) ES2060712T3 (xx)
FI (1) FI98063C (xx)
HK (1) HK49496A (xx)
HU (1) HU207993B (xx)
IE (2) IE63477B1 (xx)
IL (1) IL91941A (xx)
MY (1) MY105067A (xx)
NO (1) NO174623C (xx)
NZ (1) NZ230973A (xx)
RO (1) RO109732B1 (xx)
SG (1) SG139553A1 (xx)
SK (1) SK280845B6 (xx)
WO (1) WO1990003962A1 (xx)
YU (1) YU48466B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118853A (en) * 1988-10-13 1992-06-02 Sandoz Ltd. Processes for the synthesis of 3-disubstituted aminoacroleins
US5290946A (en) * 1988-10-13 1994-03-01 Sandoz Ltd. Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
AU637408B2 (en) * 1989-10-10 1993-05-27 Glaxo Group Limited Substituted N-vinyl imidazole derivatives.
DE4424525A1 (de) * 1994-07-12 1995-01-26 Elmar Meyer Dauermagnet-Kolbenmotor
GT199800127A (es) 1997-08-29 2000-02-01 Combinaciones terapeuticas.
DK1216038T3 (da) 1999-08-30 2005-12-27 Sanofi Aventis Deutschland Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
CN1217930C (zh) * 2000-05-26 2005-09-07 西巴特殊化学品控股有限公司 吲哚衍生物的制备方法和该方法的中间体
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
WO2004094377A1 (ja) * 2003-04-24 2004-11-04 Daicel Chemical Industries Ltd. 光学活性なジヒドロキシヘプテン酸エステルの分離方法
US7368468B2 (en) 2003-06-18 2008-05-06 Teva Pharmaceutical Industries Ltd. Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
EP1780200A1 (en) 2003-06-18 2007-05-02 Teva Pharmaceutical Industries Limited A crystalline form of fluvastatin sodium and a process for preparing it
US7368581B2 (en) 2003-06-18 2008-05-06 Teva Pharmaceutical Industries Ltd. Process for the preparation of fluvastatin sodium crystal from XIV
WO2005053683A1 (en) 2003-11-26 2005-06-16 Duke University A method of preventing or treating glaucoma
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
DE602006006899D1 (de) 2006-04-20 2009-07-02 Italiana Sint Spa Verfahren zur Herstellung von Fluvastatin-Natrium
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
SI2373609T1 (sl) 2008-12-19 2013-12-31 Krka, D.D., Novo Mesto Uporaba amfifilnih spojin za kontrolirano kristalizacijo statinov in intermediatov statinov
WO2013113067A1 (en) 2012-02-02 2013-08-08 The University Of Sydney Improvements in tear film stability
KR101695582B1 (ko) 2013-04-17 2017-01-13 화이자 인코포레이티드 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB945536A (en) * 1961-09-08 1964-01-02 Istituto Chemioterapico Method of preparing ª -amino-acroleins
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
HU204253B (en) * 1982-11-22 1991-12-30 Sandoz Ag Process for producing mevalonolactone analogues and derivatives and pharmaceutical compositions containing them
US4571428A (en) * 1983-07-08 1986-02-18 Sandoz, Inc. 6-Substituted-4-hydroxy-tetrahydropyran-2-ones
US4650890A (en) * 1984-04-03 1987-03-17 Sandoz Corp. Preparation of olefinic compounds and intermediates thereof
WO1986000307A2 (en) * 1984-06-22 1986-01-16 Sandoz Ag Pyrazole analogs of mevalonolactone and derivatives thereof, processes for their production and their use
DE3581638D1 (de) * 1984-12-04 1991-03-07 Sandoz Ag Inden-analoga von mevalonolakton und ihre derivate.
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
EP0244364A3 (en) * 1986-04-30 1992-04-01 Sandoz Ag Preparation of olefinic compounds
IL83821A0 (en) * 1986-09-10 1988-02-29 Sandoz Ag Azaindole and indolizine derivatives,their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPH03501735A (ja) 1991-04-18
EP0562643A3 (en) 1994-05-18
FI98063B (fi) 1996-12-31
HUT53860A (en) 1990-12-28
EP0363934B1 (en) 1993-12-29
NO174623C (no) 1994-06-08
RO109732B1 (ro) 1995-05-30
NO174623B (no) 1994-02-28
IE63477B1 (en) 1995-04-19
NZ230973A (en) 1993-03-26
NO902598D0 (no) 1990-06-12
EP0562643A2 (en) 1993-09-29
SG139553A1 (en) 2008-02-29
JP2853227B2 (ja) 1999-02-03
CZ579789A3 (en) 1997-11-12
FI98063C (fi) 1997-04-10
SK579789A3 (en) 2000-08-14
KR0162656B1 (ko) 1999-01-15
IE893277L (en) 1990-04-13
CA2000553C (en) 2001-12-04
AU636122B2 (en) 1993-04-22
DK144690A (da) 1990-06-13
IL91941A0 (en) 1990-06-10
CZ283316B6 (cs) 1998-02-18
ES2060712T3 (es) 1994-12-01
IL91941A (en) 1994-10-21
DK175073B1 (da) 2004-05-24
AU4344889A (en) 1990-05-01
EP0363934A1 (en) 1990-04-18
FI902935A0 (fi) 1990-06-12
CA2000553A1 (en) 1990-04-13
ATE99281T1 (de) 1994-01-15
BG60555B1 (en) 1995-08-28
DE68911834D1 (de) 1994-02-10
WO1990003962A1 (en) 1990-04-19
DK144690D0 (da) 1990-06-13
YU197389A (en) 1990-12-31
BG92179A (bg) 1993-12-24
NO902598L (no) 1990-08-07
SK280845B6 (sk) 2000-08-14
IE940109L (en) 1990-04-13
HU207993B (en) 1993-07-28
YU48466B (sh) 1998-08-14
HU896048D0 (en) 1990-11-28
DE68911834T2 (de) 1994-06-23
MY105067A (en) 1994-07-30
KR900701723A (ko) 1990-12-04

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20091010