HK49496A - Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof - Google Patents
Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereofInfo
- Publication number
- HK49496A HK49496A HK49496A HK49496A HK49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A
- Authority
- HK
- Hong Kong
- Prior art keywords
- enoic
- hept
- derivatives
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
- C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25747588A | 1988-10-13 | 1988-10-13 | |
US35553189A | 1989-05-22 | 1989-05-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK49496A true HK49496A (en) | 1996-03-29 |
Family
ID=26945992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK49496A HK49496A (en) | 1988-10-13 | 1996-03-21 | Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof |
Country Status (24)
Country | Link |
---|---|
EP (2) | EP0363934B1 (fi) |
JP (1) | JP2853227B2 (fi) |
KR (1) | KR0162656B1 (fi) |
AT (1) | ATE99281T1 (fi) |
AU (1) | AU636122B2 (fi) |
BG (1) | BG60555B1 (fi) |
CA (1) | CA2000553C (fi) |
CZ (1) | CZ283316B6 (fi) |
DE (1) | DE68911834T2 (fi) |
DK (1) | DK175073B1 (fi) |
ES (1) | ES2060712T3 (fi) |
FI (1) | FI98063C (fi) |
HK (1) | HK49496A (fi) |
HU (1) | HU207993B (fi) |
IE (2) | IE63477B1 (fi) |
IL (1) | IL91941A (fi) |
MY (1) | MY105067A (fi) |
NO (1) | NO174623C (fi) |
NZ (1) | NZ230973A (fi) |
RO (1) | RO109732B1 (fi) |
SG (1) | SG139553A1 (fi) |
SK (1) | SK280845B6 (fi) |
WO (1) | WO1990003962A1 (fi) |
YU (1) | YU48466B (fi) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5290946A (en) * | 1988-10-13 | 1994-03-01 | Sandoz Ltd. | Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes |
US5118853A (en) * | 1988-10-13 | 1992-06-02 | Sandoz Ltd. | Processes for the synthesis of 3-disubstituted aminoacroleins |
IE903606A1 (en) * | 1989-10-10 | 1991-04-24 | Glaxo Group Ltd | Chemical compounds |
DE4424525A1 (de) * | 1994-07-12 | 1995-01-26 | Elmar Meyer | Dauermagnet-Kolbenmotor |
GT199800127A (es) | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
DE60022525T2 (de) | 1999-08-30 | 2006-06-14 | Sanofi Aventis Deutschland | Ramipril zur vorbeugung von kardiovaskulären vorfällen |
EP1284964A1 (en) * | 2000-05-26 | 2003-02-26 | Ciba SC Holding AG | Process for the preparation of indole derivatives and intermediates of the process |
US7777006B2 (en) | 2002-12-31 | 2010-08-17 | Csl Behring L.L.C. | Method for purification of alpha-1-antitrypsin |
EP1623976A4 (en) * | 2003-04-24 | 2008-07-30 | Daicel Chem | PROCESS FOR SEPARATING OPTICALLY ACTIVE DIHYDROXY-HEPTENOIC ACID ESTERS |
US7368581B2 (en) | 2003-06-18 | 2008-05-06 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of fluvastatin sodium crystal from XIV |
US7368468B2 (en) | 2003-06-18 | 2008-05-06 | Teva Pharmaceutical Industries Ltd. | Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them |
CA2613021A1 (en) | 2003-06-18 | 2004-12-29 | Teva Pharmaceutical Industries Ltd | Fluvastatin sodium crystal form lxxx, processes for preparing, compositions and methods of using |
WO2005053683A1 (en) | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
US7851624B2 (en) | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
US20060211752A1 (en) | 2004-03-16 | 2006-09-21 | Kohn Leonard D | Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
ATE431818T1 (de) | 2006-04-20 | 2009-06-15 | Italiana Sint Spa | Verfahren zur herstellung von fluvastatin-natrium |
WO2010069593A1 (en) | 2008-12-19 | 2010-06-24 | Krka, D. D., Novo Mesto | Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates |
EP2327682A1 (en) | 2009-10-29 | 2011-06-01 | KRKA, D.D., Novo Mesto | Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates |
JP6224624B2 (ja) | 2012-02-02 | 2017-11-01 | ザ・ユニバーシティ・オブ・シドニー | 涙膜安定性における改善 |
EP2986599A1 (en) | 2013-04-17 | 2016-02-24 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CA3125765A1 (en) | 2019-01-18 | 2020-07-23 | Astrazeneca Ab | Pcsk9 inhibitors and methods of use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB945536A (en) * | 1961-09-08 | 1964-01-02 | Istituto Chemioterapico | Method of preparing ª -amino-acroleins |
US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
WO1984002131A1 (en) * | 1982-11-22 | 1984-06-07 | Sandoz Ag | Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
US4571428A (en) * | 1983-07-08 | 1986-02-18 | Sandoz, Inc. | 6-Substituted-4-hydroxy-tetrahydropyran-2-ones |
US4650890A (en) * | 1984-04-03 | 1987-03-17 | Sandoz Corp. | Preparation of olefinic compounds and intermediates thereof |
JPS61502467A (ja) * | 1984-06-22 | 1986-10-30 | サンド・アクチエンゲゼルシヤフト | メバロノラクトンのピラゾ−ル同族体およびその誘導体、それらの製造方法ならびに用途 |
EP0216785B1 (en) * | 1984-12-04 | 1991-01-30 | Sandoz Ag | Indene analogs of mevalonolactone and derivatives thereof |
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
EP0244364A3 (en) * | 1986-04-30 | 1992-04-01 | Sandoz Ag | Preparation of olefinic compounds |
PT85662B (pt) * | 1986-09-10 | 1990-06-29 | Sandoz Sa | Processo para a preparacao de derivados de aza-indol e de indolizina e de composicoes farmaceuticas que os contem |
-
1989
- 1989-10-11 EP EP89118906A patent/EP0363934B1/en not_active Expired - Lifetime
- 1989-10-11 KR KR1019900701243A patent/KR0162656B1/ko not_active IP Right Cessation
- 1989-10-11 AT AT89118906T patent/ATE99281T1/de not_active IP Right Cessation
- 1989-10-11 JP JP1510605A patent/JP2853227B2/ja not_active Expired - Lifetime
- 1989-10-11 EP EP19930106005 patent/EP0562643A3/en not_active Ceased
- 1989-10-11 NZ NZ230973A patent/NZ230973A/xx unknown
- 1989-10-11 AU AU43448/89A patent/AU636122B2/en not_active Expired
- 1989-10-11 HU HU896048A patent/HU207993B/hu unknown
- 1989-10-11 IL IL9194189A patent/IL91941A/en not_active IP Right Cessation
- 1989-10-11 DE DE68911834T patent/DE68911834T2/de not_active Expired - Lifetime
- 1989-10-11 IE IE327789A patent/IE63477B1/en not_active IP Right Cessation
- 1989-10-11 WO PCT/EP1989/001201 patent/WO1990003962A1/en active IP Right Grant
- 1989-10-11 MY MYPI89001403A patent/MY105067A/en unknown
- 1989-10-11 SG SG200602066-3A patent/SG139553A1/en unknown
- 1989-10-11 RO RO145326A patent/RO109732B1/ro unknown
- 1989-10-11 YU YU197389A patent/YU48466B/sh unknown
- 1989-10-11 IE IE940109A patent/IE940109L/xx unknown
- 1989-10-11 ES ES89118906T patent/ES2060712T3/es not_active Expired - Lifetime
- 1989-10-12 CZ CS895797A patent/CZ283316B6/cs not_active IP Right Cessation
- 1989-10-12 SK SK5797-89A patent/SK280845B6/sk unknown
- 1989-10-12 CA CA002000553A patent/CA2000553C/en not_active Expired - Lifetime
-
1990
- 1990-06-07 BG BG92179A patent/BG60555B1/bg unknown
- 1990-06-12 FI FI902935A patent/FI98063C/fi active IP Right Grant
- 1990-06-12 NO NO902598A patent/NO174623C/no unknown
- 1990-06-13 DK DK199001446A patent/DK175073B1/da not_active IP Right Cessation
-
1996
- 1996-03-21 HK HK49496A patent/HK49496A/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20091010 |