HK1494A - Fluorinated benzyl triazole compounds - Google Patents

Fluorinated benzyl triazole compounds Download PDF

Info

Publication number
HK1494A
HK1494A HK14/94A HK1494A HK1494A HK 1494 A HK1494 A HK 1494A HK 14/94 A HK14/94 A HK 14/94A HK 1494 A HK1494 A HK 1494A HK 1494 A HK1494 A HK 1494A
Authority
HK
Hong Kong
Prior art keywords
carbamoyl
triazole
chlorine
formula
alkylcarbamoyl
Prior art date
Application number
HK14/94A
Other languages
German (de)
English (en)
French (fr)
Inventor
Rene Meier
Original Assignee
Ciba-Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba-Geigy Ag filed Critical Ciba-Geigy Ag
Publication of HK1494A publication Critical patent/HK1494A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK14/94A 1985-04-18 1994-01-06 Fluorinated benzyl triazole compounds HK1494A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (1)

Publication Number Publication Date
HK1494A true HK1494A (en) 1994-01-14

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14/94A HK1494A (en) 1985-04-18 1994-01-06 Fluorinated benzyl triazole compounds

Country Status (22)

Country Link
EP (1) EP0199262B1 (enExample)
JP (1) JPS61243068A (enExample)
KR (1) KR900008810B1 (enExample)
AU (1) AU599024B2 (enExample)
CA (1) CA1272201A (enExample)
CY (1) CY1751A (enExample)
DD (1) DD245874A5 (enExample)
DE (1) DE3677626D1 (enExample)
DK (1) DK169720B1 (enExample)
ES (2) ES8800176A1 (enExample)
FI (1) FI93544C (enExample)
GR (1) GR861004B (enExample)
HK (1) HK1494A (enExample)
HU (1) HU203327B (enExample)
IE (1) IE58472B1 (enExample)
IL (1) IL78510A (enExample)
MX (1) MX9203628A (enExample)
NO (1) NO164295C (enExample)
NZ (1) NZ215871A (enExample)
PH (1) PH22568A (enExample)
PT (1) PT82400B (enExample)
ZA (1) ZA862873B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3578499D1 (de) * 1984-02-02 1990-08-09 Merck & Co Inc 5-(amino oder substituiertes amino)-1,2,3-triazole.
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
PL189232B1 (pl) 1996-07-11 2005-07-29 Novartis Ag Sposób wytwarzania 1-podstawionych 4-cyjano-1,2,3-triazoli
TW403740B (en) 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
JP2013525413A (ja) * 2010-04-30 2013-06-20 ラボラトリオス レスヴィ，エス．エル． ルフィナマイド中間体の改良された製造方法
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014120994A1 (en) * 2013-01-31 2014-08-07 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
US12023322B2 (en) 2015-12-11 2024-07-02 Aarhus Universitet Rufinamide for use in the treatment of myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide
CN116874438A (zh) * 2023-06-02 2023-10-13 大连理工大学 一锅法制备多取代1,2,3-三唑类化合物
CN116854644B (zh) * 2023-07-06 2025-10-21 浙江大学 5-氨基-1-烷基-1h-1,2,3-三氮唑-4-甲酰胺类化合物及其制备和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A7 (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
HUT40792A (en) 1987-02-27
GR861004B (en) 1986-08-12
IL78510A0 (en) 1986-08-31
JPS61243068A (ja) 1986-10-29
PT82400B (pt) 1988-08-17
ES8800176A1 (es) 1987-10-16
NZ215871A (en) 1989-01-27
FI93544B (fi) 1995-01-13
DK169720B1 (da) 1995-01-23
FI93544C (fi) 1995-04-25
EP0199262A2 (de) 1986-10-29
AU599024B2 (en) 1990-07-12
HU203327B (en) 1991-07-29
CY1751A (en) 1994-06-03
NO861486L (no) 1986-10-20
KR900008810B1 (ko) 1990-11-30
IE861015L (en) 1986-10-18
DK175686A (da) 1986-10-19
EP0199262B1 (de) 1991-02-27
FI861573A0 (fi) 1986-04-14
ES8802501A1 (es) 1988-07-01
ES557641A0 (es) 1988-07-01
PH22568A (en) 1988-10-17
DD245874A5 (de) 1987-05-20
KR860008152A (ko) 1986-11-12
NO164295C (no) 1990-09-19
JPH0564949B2 (enExample) 1993-09-16
PT82400A (en) 1986-05-01
IE58472B1 (en) 1993-09-22
NO164295B (no) 1990-06-11
IL78510A (en) 1992-05-25
ES554024A0 (es) 1987-10-16
CA1272201A (en) 1990-07-31
DE3677626D1 (de) 1991-04-04
DK175686D0 (da) 1986-04-17
MX9203628A (es) 1992-09-01
EP0199262A3 (en) 1987-08-26
ZA862873B (en) 1986-12-30
AU5631986A (en) 1986-10-23
FI861573A7 (fi) 1986-10-19

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Effective date: 20060414