AU5631986A - Fluorinated benzyltriazoles - Google Patents

Fluorinated benzyltriazoles

Info

Publication number
AU5631986A
AU5631986A AU56319/86A AU5631986A AU5631986A AU 5631986 A AU5631986 A AU 5631986A AU 56319/86 A AU56319/86 A AU 56319/86A AU 5631986 A AU5631986 A AU 5631986A AU 5631986 A AU5631986 A AU 5631986A
Authority
AU
Australia
Prior art keywords
benzyltriazoles
fluorinated
fluorinated benzyltriazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU56319/86A
Other versions
AU599024B2 (en
Inventor
Rene Meier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU5631986A publication Critical patent/AU5631986A/en
Application granted granted Critical
Publication of AU599024B2 publication Critical patent/AU599024B2/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Request to Amend Deed and Register Assignors: CIBA-GEIGY AG
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU56319/86A 1985-04-18 1986-04-17 Fluorinated benzyltriazoles Expired AU599024B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18
CH1663/85 1985-04-18

Publications (2)

Publication Number Publication Date
AU5631986A true AU5631986A (en) 1986-10-23
AU599024B2 AU599024B2 (en) 1990-07-12

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56319/86A Expired AU599024B2 (en) 1985-04-18 1986-04-17 Fluorinated benzyltriazoles

Country Status (22)

Country Link
EP (1) EP0199262B1 (en)
JP (1) JPS61243068A (en)
KR (1) KR900008810B1 (en)
AU (1) AU599024B2 (en)
CA (1) CA1272201A (en)
CY (1) CY1751A (en)
DD (1) DD245874A5 (en)
DE (1) DE3677626D1 (en)
DK (1) DK169720B1 (en)
ES (2) ES8800176A1 (en)
FI (1) FI93544C (en)
GR (1) GR861004B (en)
HK (1) HK1494A (en)
HU (1) HU203327B (en)
IE (1) IE58472B1 (en)
IL (1) IL78510A (en)
MX (1) MX9203628A (en)
NO (1) NO164295C (en)
NZ (1) NZ215871A (en)
PH (1) PH22568A (en)
PT (1) PT82400B (en)
ZA (1) ZA862873B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598067B2 (en) * 1984-02-02 1990-06-14 Merck & Co., Inc. 5-amino or substituted amino 1,2,3-triazoles

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
BR9710252B1 (en) * 1996-07-11 2010-06-29 process for preparing 4-substituted 4-cyano-1,2,3-triazoles.
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (en) * 2009-03-23 2012-04-20 Dipharma Francis Srl METHOD FOR THE PREPARATION OF RUFINAMIDE
IT1395736B1 (en) 2009-08-04 2012-10-19 Dipharma Francis Srl CRYSTALLINE FORMS OF RUFINAMIDE
WO2011135105A1 (en) * 2010-04-30 2011-11-03 Laboratorios Lesvi, S.L. Improved process for preparing rufinamide intermediate
ITMI20110718A1 (en) 2011-04-29 2012-10-30 Dipharma Francis Srl PROCEDURE FOR PURIFICATION OF RUFINAMIDE
WO2014120994A1 (en) * 2013-01-31 2014-08-07 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
CA3008048C (en) 2015-12-11 2023-11-14 Aarhus Universitet Rufinamide for use in the treatment of myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (en) * 1982-12-23 1984-06-24 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA ARALKYLTRIAZOLFOERENINGAR.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598067B2 (en) * 1984-02-02 1990-06-14 Merck & Co., Inc. 5-amino or substituted amino 1,2,3-triazoles

Also Published As

Publication number Publication date
AU599024B2 (en) 1990-07-12
ES557641A0 (en) 1988-07-01
HU203327B (en) 1991-07-29
DK175686D0 (en) 1986-04-17
CA1272201A (en) 1990-07-31
NZ215871A (en) 1989-01-27
DE3677626D1 (en) 1991-04-04
FI861573A0 (en) 1986-04-14
NO861486L (en) 1986-10-20
PH22568A (en) 1988-10-17
DK175686A (en) 1986-10-19
PT82400A (en) 1986-05-01
IE58472B1 (en) 1993-09-22
FI93544B (en) 1995-01-13
DK169720B1 (en) 1995-01-23
KR900008810B1 (en) 1990-11-30
PT82400B (en) 1988-08-17
KR860008152A (en) 1986-11-12
HUT40792A (en) 1987-02-27
ES554024A0 (en) 1987-10-16
GR861004B (en) 1986-08-12
ES8800176A1 (en) 1987-10-16
EP0199262A2 (en) 1986-10-29
JPH0564949B2 (en) 1993-09-16
HK1494A (en) 1994-01-14
IE861015L (en) 1986-10-18
ES8802501A1 (en) 1988-07-01
MX9203628A (en) 1992-09-01
EP0199262A3 (en) 1987-08-26
FI93544C (en) 1995-04-25
JPS61243068A (en) 1986-10-29
IL78510A (en) 1992-05-25
CY1751A (en) 1994-06-03
NO164295C (en) 1990-09-19
NO164295B (en) 1990-06-11
ZA862873B (en) 1986-12-30
FI861573A (en) 1986-10-19
EP0199262B1 (en) 1991-02-27
DD245874A5 (en) 1987-05-20
IL78510A0 (en) 1986-08-31

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