NO164295C - ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE FLUORED BENZYLTRIAZOL COMPOUNDS. - Google Patents

ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE FLUORED BENZYLTRIAZOL COMPOUNDS.

Info

Publication number
NO164295C
NO164295C NO861486A NO861486A NO164295C NO 164295 C NO164295 C NO 164295C NO 861486 A NO861486 A NO 861486A NO 861486 A NO861486 A NO 861486A NO 164295 C NO164295 C NO 164295C
Authority
NO
Norway
Prior art keywords
fluored
benzyltriazol
compounds
preparation
therapeutic active
Prior art date
Application number
NO861486A
Other languages
Norwegian (no)
Other versions
NO861486L (en
NO164295B (en
Inventor
Rene Meier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO861486L publication Critical patent/NO861486L/en
Publication of NO164295B publication Critical patent/NO164295B/en
Publication of NO164295C publication Critical patent/NO164295C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO861486A 1985-04-18 1986-04-16 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE FLUORED BENZYLTRIAZOL COMPOUNDS. NO164295C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (3)

Publication Number Publication Date
NO861486L NO861486L (en) 1986-10-20
NO164295B NO164295B (en) 1990-06-11
NO164295C true NO164295C (en) 1990-09-19

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO861486A NO164295C (en) 1985-04-18 1986-04-16 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE FLUORED BENZYLTRIAZOL COMPOUNDS.

Country Status (22)

Country Link
EP (1) EP0199262B1 (en)
JP (1) JPS61243068A (en)
KR (1) KR900008810B1 (en)
AU (1) AU599024B2 (en)
CA (1) CA1272201A (en)
CY (1) CY1751A (en)
DD (1) DD245874A5 (en)
DE (1) DE3677626D1 (en)
DK (1) DK169720B1 (en)
ES (2) ES8800176A1 (en)
FI (1) FI93544C (en)
GR (1) GR861004B (en)
HK (1) HK1494A (en)
HU (1) HU203327B (en)
IE (1) IE58472B1 (en)
IL (1) IL78510A (en)
MX (1) MX9203628A (en)
NO (1) NO164295C (en)
NZ (1) NZ215871A (en)
PH (1) PH22568A (en)
PT (1) PT82400B (en)
ZA (1) ZA862873B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
AU719148B2 (en) 1996-07-11 2000-05-04 Novartis Ag Process for preparing 1-substituted 4-cyano-1,2,3-triazoles
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (en) * 2009-03-23 2012-04-20 Dipharma Francis Srl METHOD FOR THE PREPARATION OF RUFINAMIDE
IT1395736B1 (en) 2009-08-04 2012-10-19 Dipharma Francis Srl CRYSTALLINE FORMS OF RUFINAMIDE
WO2011135105A1 (en) * 2010-04-30 2011-11-03 Laboratorios Lesvi, S.L. Improved process for preparing rufinamide intermediate
ITMI20110718A1 (en) 2011-04-29 2012-10-30 Dipharma Francis Srl PROCEDURE FOR PURIFICATION OF RUFINAMIDE
US20150368211A1 (en) * 2013-01-31 2015-12-24 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
CN108697662A (en) 2015-12-11 2018-10-23 奥胡斯大学 Rufinamide for treating myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (en) * 1982-12-23 1984-06-24 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA ARALKYLTRIAZOLFOERENINGAR.

Also Published As

Publication number Publication date
DK169720B1 (en) 1995-01-23
ES8800176A1 (en) 1987-10-16
HU203327B (en) 1991-07-29
DK175686A (en) 1986-10-19
JPS61243068A (en) 1986-10-29
IL78510A (en) 1992-05-25
GR861004B (en) 1986-08-12
FI93544B (en) 1995-01-13
PT82400B (en) 1988-08-17
EP0199262B1 (en) 1991-02-27
FI93544C (en) 1995-04-25
IE58472B1 (en) 1993-09-22
KR900008810B1 (en) 1990-11-30
JPH0564949B2 (en) 1993-09-16
AU5631986A (en) 1986-10-23
DE3677626D1 (en) 1991-04-04
HUT40792A (en) 1987-02-27
ZA862873B (en) 1986-12-30
NO861486L (en) 1986-10-20
NO164295B (en) 1990-06-11
ES554024A0 (en) 1987-10-16
ES557641A0 (en) 1988-07-01
IE861015L (en) 1986-10-18
KR860008152A (en) 1986-11-12
EP0199262A3 (en) 1987-08-26
FI861573A0 (en) 1986-04-14
NZ215871A (en) 1989-01-27
MX9203628A (en) 1992-09-01
ES8802501A1 (en) 1988-07-01
AU599024B2 (en) 1990-07-12
IL78510A0 (en) 1986-08-31
CA1272201A (en) 1990-07-31
FI861573A (en) 1986-10-19
DK175686D0 (en) 1986-04-17
PH22568A (en) 1988-10-17
CY1751A (en) 1994-06-03
DD245874A5 (en) 1987-05-20
HK1494A (en) 1994-01-14
PT82400A (en) 1986-05-01
EP0199262A2 (en) 1986-10-29

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