FI861573A0 - Process for the preparation of fluorinated anticonvulsant 1-benzyl-1H-1,2,3-triazole compounds - Google Patents

Process for the preparation of fluorinated anticonvulsant 1-benzyl-1H-1,2,3-triazole compounds

Info

Publication number
FI861573A0
FI861573A0 FI861573A FI861573A FI861573A0 FI 861573 A0 FI861573 A0 FI 861573A0 FI 861573 A FI861573 A FI 861573A FI 861573 A FI861573 A FI 861573A FI 861573 A0 FI861573 A0 FI 861573A0
Authority
FI
Finland
Prior art keywords
anticonvulsant
fluorinated
benzyl
preparation
triazole compounds
Prior art date
Application number
FI861573A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI93544C (en
FI93544B (en
FI861573A (en
Inventor
Rene Meier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI861573A0 publication Critical patent/FI861573A0/en
Publication of FI861573A publication Critical patent/FI861573A/en
Application granted granted Critical
Publication of FI93544B publication Critical patent/FI93544B/en
Publication of FI93544C publication Critical patent/FI93544C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
FI861573A 1985-04-18 1986-04-14 Process for the preparation of fluorinated 1-benzyl-1H-1,2,3-triazole compounds with anticonvulsant action FI93544C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18
CH166385 1985-04-18

Publications (4)

Publication Number Publication Date
FI861573A0 true FI861573A0 (en) 1986-04-14
FI861573A FI861573A (en) 1986-10-19
FI93544B FI93544B (en) 1995-01-13
FI93544C FI93544C (en) 1995-04-25

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861573A FI93544C (en) 1985-04-18 1986-04-14 Process for the preparation of fluorinated 1-benzyl-1H-1,2,3-triazole compounds with anticonvulsant action

Country Status (22)

Country Link
EP (1) EP0199262B1 (en)
JP (1) JPS61243068A (en)
KR (1) KR900008810B1 (en)
AU (1) AU599024B2 (en)
CA (1) CA1272201A (en)
CY (1) CY1751A (en)
DD (1) DD245874A5 (en)
DE (1) DE3677626D1 (en)
DK (1) DK169720B1 (en)
ES (2) ES8800176A1 (en)
FI (1) FI93544C (en)
GR (1) GR861004B (en)
HK (1) HK1494A (en)
HU (1) HU203327B (en)
IE (1) IE58472B1 (en)
IL (1) IL78510A (en)
MX (1) MX9203628A (en)
NO (1) NO164295C (en)
NZ (1) NZ215871A (en)
PH (1) PH22568A (en)
PT (1) PT82400B (en)
ZA (1) ZA862873B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
KR100481137B1 (en) * 1996-07-11 2005-04-08 노파르티스 아게 Process for preparing 1-substituted 4-cyano-1,2,3-triazoles
TW403740B (en) 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (en) * 2009-03-23 2012-04-20 Dipharma Francis Srl METHOD FOR THE PREPARATION OF RUFINAMIDE
IT1395736B1 (en) 2009-08-04 2012-10-19 Dipharma Francis Srl CRYSTALLINE FORMS OF RUFINAMIDE
US8884026B2 (en) * 2010-04-30 2014-11-11 Laboratorios Lesvi, S.L. Process for preparing rufinamide intermediate
ITMI20110718A1 (en) 2011-04-29 2012-10-30 Dipharma Francis Srl PROCEDURE FOR PURIFICATION OF RUFINAMIDE
US20150368211A1 (en) * 2013-01-31 2015-12-24 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
ES2902685T3 (en) 2015-12-11 2022-03-29 Univ Aarhus Rufinamide for use in the treatment of myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (en) * 1982-12-23 1984-06-24 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA ARALKYLTRIAZOLFOERENINGAR.

Also Published As

Publication number Publication date
DK175686D0 (en) 1986-04-17
DD245874A5 (en) 1987-05-20
FI93544C (en) 1995-04-25
NZ215871A (en) 1989-01-27
ES8802501A1 (en) 1988-07-01
NO861486L (en) 1986-10-20
KR900008810B1 (en) 1990-11-30
PH22568A (en) 1988-10-17
ZA862873B (en) 1986-12-30
DE3677626D1 (en) 1991-04-04
MX9203628A (en) 1992-09-01
ES557641A0 (en) 1988-07-01
IE58472B1 (en) 1993-09-22
PT82400B (en) 1988-08-17
HU203327B (en) 1991-07-29
HUT40792A (en) 1987-02-27
IL78510A0 (en) 1986-08-31
NO164295C (en) 1990-09-19
GR861004B (en) 1986-08-12
KR860008152A (en) 1986-11-12
JPS61243068A (en) 1986-10-29
FI93544B (en) 1995-01-13
NO164295B (en) 1990-06-11
IE861015L (en) 1986-10-18
AU5631986A (en) 1986-10-23
ES8800176A1 (en) 1987-10-16
IL78510A (en) 1992-05-25
DK169720B1 (en) 1995-01-23
FI861573A (en) 1986-10-19
JPH0564949B2 (en) 1993-09-16
CY1751A (en) 1994-06-03
DK175686A (en) 1986-10-19
EP0199262A3 (en) 1987-08-26
CA1272201A (en) 1990-07-31
ES554024A0 (en) 1987-10-16
EP0199262A2 (en) 1986-10-29
HK1494A (en) 1994-01-14
AU599024B2 (en) 1990-07-12
PT82400A (en) 1986-05-01
EP0199262B1 (en) 1991-02-27

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired