DK175686A - FLUORATED 1- (ALFA-PHENYLALKYL) -1H-1,2,3-TRIAZOLE COMPOUNDS AND THEIR PREPARATION AND USE - Google Patents

FLUORATED 1- (ALFA-PHENYLALKYL) -1H-1,2,3-TRIAZOLE COMPOUNDS AND THEIR PREPARATION AND USE Download PDF

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Publication number
DK175686A
DK175686A DK175686A DK175686A DK175686A DK 175686 A DK175686 A DK 175686A DK 175686 A DK175686 A DK 175686A DK 175686 A DK175686 A DK 175686A DK 175686 A DK175686 A DK 175686A
Authority
DK
Denmark
Prior art keywords
fluorated
phenylalkyl
alfa
preparation
triazole compounds
Prior art date
Application number
DK175686A
Other languages
Danish (da)
Other versions
DK169720B1 (en
DK175686D0 (en
Inventor
Rene Meier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK175686D0 publication Critical patent/DK175686D0/en
Publication of DK175686A publication Critical patent/DK175686A/en
Application granted granted Critical
Publication of DK169720B1 publication Critical patent/DK169720B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK175686A 1985-04-18 1986-04-17 Fluorinated 1- (alpha-phenylalkyl) -1H-1,2,3-triazole compounds as well as their preparation and pharmaceutical preparations containing such compounds DK169720B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18
CH166385 1985-04-18

Publications (3)

Publication Number Publication Date
DK175686D0 DK175686D0 (en) 1986-04-17
DK175686A true DK175686A (en) 1986-10-19
DK169720B1 DK169720B1 (en) 1995-01-23

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
DK175686A DK169720B1 (en) 1985-04-18 1986-04-17 Fluorinated 1- (alpha-phenylalkyl) -1H-1,2,3-triazole compounds as well as their preparation and pharmaceutical preparations containing such compounds

Country Status (22)

Country Link
EP (1) EP0199262B1 (en)
JP (1) JPS61243068A (en)
KR (1) KR900008810B1 (en)
AU (1) AU599024B2 (en)
CA (1) CA1272201A (en)
CY (1) CY1751A (en)
DD (1) DD245874A5 (en)
DE (1) DE3677626D1 (en)
DK (1) DK169720B1 (en)
ES (2) ES8800176A1 (en)
FI (1) FI93544C (en)
GR (1) GR861004B (en)
HK (1) HK1494A (en)
HU (1) HU203327B (en)
IE (1) IE58472B1 (en)
IL (1) IL78510A (en)
MX (1) MX9203628A (en)
NO (1) NO164295C (en)
NZ (1) NZ215871A (en)
PH (1) PH22568A (en)
PT (1) PT82400B (en)
ZA (1) ZA862873B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
AU719148B2 (en) 1996-07-11 2000-05-04 Novartis Ag Process for preparing 1-substituted 4-cyano-1,2,3-triazoles
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (en) * 2009-03-23 2012-04-20 Dipharma Francis Srl METHOD FOR THE PREPARATION OF RUFINAMIDE
IT1395736B1 (en) 2009-08-04 2012-10-19 Dipharma Francis Srl CRYSTALLINE FORMS OF RUFINAMIDE
WO2011135105A1 (en) * 2010-04-30 2011-11-03 Laboratorios Lesvi, S.L. Improved process for preparing rufinamide intermediate
ITMI20110718A1 (en) 2011-04-29 2012-10-30 Dipharma Francis Srl PROCEDURE FOR PURIFICATION OF RUFINAMIDE
US20150368211A1 (en) * 2013-01-31 2015-12-24 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
CN108697662A (en) 2015-12-11 2018-10-23 奥胡斯大学 Rufinamide for treating myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (en) * 1982-12-23 1984-06-24 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA ARALKYLTRIAZOLFOERENINGAR.

Also Published As

Publication number Publication date
DK169720B1 (en) 1995-01-23
ES8800176A1 (en) 1987-10-16
HU203327B (en) 1991-07-29
JPS61243068A (en) 1986-10-29
IL78510A (en) 1992-05-25
GR861004B (en) 1986-08-12
FI93544B (en) 1995-01-13
PT82400B (en) 1988-08-17
EP0199262B1 (en) 1991-02-27
FI93544C (en) 1995-04-25
IE58472B1 (en) 1993-09-22
KR900008810B1 (en) 1990-11-30
NO164295C (en) 1990-09-19
JPH0564949B2 (en) 1993-09-16
AU5631986A (en) 1986-10-23
DE3677626D1 (en) 1991-04-04
HUT40792A (en) 1987-02-27
ZA862873B (en) 1986-12-30
NO861486L (en) 1986-10-20
NO164295B (en) 1990-06-11
ES554024A0 (en) 1987-10-16
ES557641A0 (en) 1988-07-01
IE861015L (en) 1986-10-18
KR860008152A (en) 1986-11-12
EP0199262A3 (en) 1987-08-26
FI861573A0 (en) 1986-04-14
NZ215871A (en) 1989-01-27
MX9203628A (en) 1992-09-01
ES8802501A1 (en) 1988-07-01
AU599024B2 (en) 1990-07-12
IL78510A0 (en) 1986-08-31
CA1272201A (en) 1990-07-31
FI861573A (en) 1986-10-19
DK175686D0 (en) 1986-04-17
PH22568A (en) 1988-10-17
CY1751A (en) 1994-06-03
DD245874A5 (en) 1987-05-20
HK1494A (en) 1994-01-14
PT82400A (en) 1986-05-01
EP0199262A2 (en) 1986-10-29

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
AHB Application shelved due to non-payment
PUP Patent expired