HK1494A - Fluorinated benzyl triazole compounds - Google Patents

Fluorinated benzyl triazole compounds Download PDF

Info

Publication number
HK1494A
HK1494A HK14/94A HK1494A HK1494A HK 1494 A HK1494 A HK 1494A HK 14/94 A HK14/94 A HK 14/94A HK 1494 A HK1494 A HK 1494A HK 1494 A HK1494 A HK 1494A
Authority
HK
Hong Kong
Prior art keywords
carbamoyl
triazole
chlorine
formula
alkylcarbamoyl
Prior art date
Application number
HK14/94A
Other languages
German (de)
English (en)
French (fr)
Inventor
Rene Meier
Original Assignee
Ciba-Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba-Geigy Ag filed Critical Ciba-Geigy Ag
Publication of HK1494A publication Critical patent/HK1494A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK14/94A 1985-04-18 1994-01-06 Fluorinated benzyl triazole compounds HK1494A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (1)

Publication Number Publication Date
HK1494A true HK1494A (en) 1994-01-14

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14/94A HK1494A (en) 1985-04-18 1994-01-06 Fluorinated benzyl triazole compounds

Country Status (22)

Country Link
EP (1) EP0199262B1 (enrdf_load_stackoverflow)
JP (1) JPS61243068A (enrdf_load_stackoverflow)
KR (1) KR900008810B1 (enrdf_load_stackoverflow)
AU (1) AU599024B2 (enrdf_load_stackoverflow)
CA (1) CA1272201A (enrdf_load_stackoverflow)
CY (1) CY1751A (enrdf_load_stackoverflow)
DD (1) DD245874A5 (enrdf_load_stackoverflow)
DE (1) DE3677626D1 (enrdf_load_stackoverflow)
DK (1) DK169720B1 (enrdf_load_stackoverflow)
ES (2) ES8800176A1 (enrdf_load_stackoverflow)
FI (1) FI93544C (enrdf_load_stackoverflow)
GR (1) GR861004B (enrdf_load_stackoverflow)
HK (1) HK1494A (enrdf_load_stackoverflow)
HU (1) HU203327B (enrdf_load_stackoverflow)
IE (1) IE58472B1 (enrdf_load_stackoverflow)
IL (1) IL78510A (enrdf_load_stackoverflow)
MX (1) MX9203628A (enrdf_load_stackoverflow)
NO (1) NO164295C (enrdf_load_stackoverflow)
NZ (1) NZ215871A (enrdf_load_stackoverflow)
PH (1) PH22568A (enrdf_load_stackoverflow)
PT (1) PT82400B (enrdf_load_stackoverflow)
ZA (1) ZA862873B (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3578499D1 (de) * 1984-02-02 1990-08-09 Merck & Co Inc 5-(amino oder substituiertes amino)-1,2,3-triazole.
WO1997040025A1 (en) * 1996-04-19 1997-10-30 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
SK283990B6 (sk) * 1996-07-11 2004-07-07 Novartis Ag Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol
TW403740B (en) * 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
JP2013525413A (ja) * 2010-04-30 2013-06-20 ラボラトリオス レスヴィ，エス．エル． ルフィナマイド中間体の改良された製造方法
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
US20150368211A1 (en) * 2013-01-31 2015-12-24 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
ES2902685T3 (es) 2015-12-11 2022-03-29 Univ Aarhus Rufinamida para uso en el tratamiento de la miotonía
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide
CN116874438A (zh) * 2023-06-02 2023-10-13 大连理工大学 一锅法制备多取代1,2,3-三唑类化合物
CN116854644A (zh) * 2023-07-06 2023-10-10 浙江大学 5-氨基-1-烷基-1h-1,2,3-三氮唑-4-甲酰胺类化合物及其制备和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A7 (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
DD245874A5 (de) 1987-05-20
DE3677626D1 (de) 1991-04-04
AU599024B2 (en) 1990-07-12
ES557641A0 (es) 1988-07-01
KR860008152A (ko) 1986-11-12
IL78510A (en) 1992-05-25
DK169720B1 (da) 1995-01-23
FI93544B (fi) 1995-01-13
DK175686A (da) 1986-10-19
CA1272201A (en) 1990-07-31
ES8800176A1 (es) 1987-10-16
MX9203628A (es) 1992-09-01
GR861004B (en) 1986-08-12
PT82400A (en) 1986-05-01
ES554024A0 (es) 1987-10-16
FI861573A0 (fi) 1986-04-14
JPH0564949B2 (enrdf_load_stackoverflow) 1993-09-16
PT82400B (pt) 1988-08-17
AU5631986A (en) 1986-10-23
KR900008810B1 (ko) 1990-11-30
PH22568A (en) 1988-10-17
IE58472B1 (en) 1993-09-22
HU203327B (en) 1991-07-29
EP0199262A2 (de) 1986-10-29
DK175686D0 (da) 1986-04-17
NZ215871A (en) 1989-01-27
IL78510A0 (en) 1986-08-31
NO861486L (no) 1986-10-20
NO164295C (no) 1990-09-19
JPS61243068A (ja) 1986-10-29
ES8802501A1 (es) 1988-07-01
ZA862873B (en) 1986-12-30
EP0199262A3 (en) 1987-08-26
FI93544C (fi) 1995-04-25
NO164295B (no) 1990-06-11
EP0199262B1 (de) 1991-02-27
FI861573A7 (fi) 1986-10-19
IE861015L (en) 1986-10-18
CY1751A (en) 1994-06-03
HUT40792A (en) 1987-02-27

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Effective date: 20060414