HK1221712A1 - 雄激素受体调节剂的酯衍生物及其使用方法 - Google Patents

雄激素受体调节剂的酯衍生物及其使用方法 Download PDF

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Publication number
HK1221712A1
HK1221712A1 HK16109321.3A HK16109321A HK1221712A1 HK 1221712 A1 HK1221712 A1 HK 1221712A1 HK 16109321 A HK16109321 A HK 16109321A HK 1221712 A1 HK1221712 A1 HK 1221712A1
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Hong Kong
Prior art keywords
compound
alkyl
independently
compounds
prostate cancer
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HK16109321.3A
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English (en)
Chinese (zh)
Inventor
．穆基王軍卡門．阿德里亞娜．巴紐埃洛斯雷蒙德．約翰．安德森哈維爾．加西亞．費爾南德斯瑪麗安娜．桃樂茜．薩達爾 納斯林．
纳斯林．R．穆基
王军
卡门．阿德里亚娜．巴纽埃洛斯
雷蒙德．约翰．安德森
哈维尔．加西亚．费尔南德斯
玛丽安娜．桃乐茜．萨达尔
Original Assignee
不列颠哥伦比亚癌症局分支机构
英属哥伦比亚大学
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51864937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1221712(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 不列颠哥伦比亚癌症局分支机构, 英属哥伦比亚大学 filed Critical 不列颠哥伦比亚癌症局分支机构
Publication of HK1221712A1 publication Critical patent/HK1221712A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/16—Acetic acid esters of dihydroxylic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/18—Acetic acid esters of trihydroxylic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16109321.3A 2013-05-10 2014-05-09 雄激素受体调节剂的酯衍生物及其使用方法 HK1221712A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361822186P 2013-05-10 2013-05-10
US61/822,186 2013-05-10
PCT/CA2014/000414 WO2014179867A1 (en) 2013-05-10 2014-05-09 Ester derivatives of androgen receptor modulators and methods for their use

Publications (1)

Publication Number Publication Date
HK1221712A1 true HK1221712A1 (zh) 2017-06-09

Family

ID=51864937

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HK16109321.3A HK1221712A1 (zh) 2013-05-10 2014-05-09 雄激素受体调节剂的酯衍生物及其使用方法

Country Status (17)

Country Link
US (2) US9173939B2 (enExample)
EP (1) EP2994451A4 (enExample)
JP (2) JP6100439B2 (enExample)
KR (2) KR101739800B1 (enExample)
CN (1) CN105358522A (enExample)
AP (1) AP2015008838A0 (enExample)
AU (2) AU2014262333B2 (enExample)
BR (1) BR112015028174A2 (enExample)
CA (1) CA2911352A1 (enExample)
CL (1) CL2015003271A1 (enExample)
HK (1) HK1221712A1 (enExample)
IL (1) IL242345A (enExample)
MX (1) MX347705B (enExample)
PE (1) PE20160091A1 (enExample)
PH (2) PH12015502525A1 (enExample)
SG (2) SG10201607177XA (enExample)
WO (1) WO2014179867A1 (enExample)

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CN102083780B (zh) 2008-07-02 2017-03-29 不列颠哥伦比亚癌症局分支机构 二缩水甘油醚衍生物治疗剂和它们的使用方法
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WO2020198712A1 (en) * 2019-03-28 2020-10-01 Essa Pharma, Inc. Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof
KR20230004498A (ko) 2020-04-17 2023-01-06 에싸 파마 아이엔씨. N-말단 도메인 안드로겐 수용체 억제제의 고형분 형태 및 이의 용도
CN113666806A (zh) * 2020-05-15 2021-11-19 上海安谱实验科技股份有限公司 一种双酚f 2,3-二羟丙基(2-氯-1-丙基)乙醚的制备方法
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Publication number Publication date
PH12016501047A1 (en) 2018-06-25
US20140335080A1 (en) 2014-11-13
US20160068466A1 (en) 2016-03-10
WO2014179867A1 (en) 2014-11-13
AU2014262333A1 (en) 2015-11-19
PH12015502525A1 (en) 2016-03-28
MX347705B (es) 2017-05-09
KR101739800B1 (ko) 2017-05-25
CN105358522A (zh) 2016-02-24
CA2911352A1 (en) 2014-11-13
EP2994451A1 (en) 2016-03-16
IL242345A (en) 2017-02-28
KR20160013072A (ko) 2016-02-03
MX2015015509A (es) 2016-08-12
EP2994451A4 (en) 2016-10-05
PE20160091A1 (es) 2016-03-03
JP2016518394A (ja) 2016-06-23
SG11201509038UA (en) 2015-12-30
AU2016228233A1 (en) 2016-10-06
AU2014262333B2 (en) 2016-06-16
CL2015003271A1 (es) 2016-04-22
JP6100439B2 (ja) 2017-03-22
JP2017125036A (ja) 2017-07-20
AP2015008838A0 (en) 2015-11-30
SG10201607177XA (en) 2016-10-28
US9173939B2 (en) 2015-11-03
BR112015028174A2 (pt) 2017-07-25
KR20170060162A (ko) 2017-05-31

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