HK1220966A1 - 鹽酸苯達莫司汀固體形式 - Google Patents

鹽酸苯達莫司汀固體形式

Info

Publication number
HK1220966A1
HK1220966A1 HK16108932.6A HK16108932A HK1220966A1 HK 1220966 A1 HK1220966 A1 HK 1220966A1 HK 16108932 A HK16108932 A HK 16108932A HK 1220966 A1 HK1220966 A1 HK 1220966A1
Authority
HK
Hong Kong
Prior art keywords
solid forms
bendamustine hydrochloride
bendamustine
hydrochloride
solid
Prior art date
Application number
HK16108932.6A
Other languages
English (en)
Inventor
伊安 庫珀 馬丁
勞倫特
庫瓦西耶
赫德爾斯頓 馬克
羅伯特
麥基恩
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41051023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1220966(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of HK1220966A1 publication Critical patent/HK1220966A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
HK16108932.6A 2008-03-26 2016-07-26 鹽酸苯達莫司汀固體形式 HK1220966A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3975208P 2008-03-26 2008-03-26

Publications (1)

Publication Number Publication Date
HK1220966A1 true HK1220966A1 (zh) 2017-05-19

Family

ID=41051023

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108932.6A HK1220966A1 (zh) 2008-03-26 2016-07-26 鹽酸苯達莫司汀固體形式

Country Status (12)

Country Link
US (9) US20090264488A1 (zh)
EP (2) EP2271315B1 (zh)
JP (1) JP5536753B2 (zh)
CN (3) CN105693620A (zh)
AR (1) AR072777A1 (zh)
CA (1) CA2718939A1 (zh)
CL (1) CL2009000742A1 (zh)
ES (1) ES2605205T3 (zh)
HK (1) HK1220966A1 (zh)
MX (2) MX339878B (zh)
TW (1) TWI472515B (zh)
WO (1) WO2009120386A2 (zh)

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US20140142153A1 (en) * 2011-01-25 2014-05-22 Dr. Reddy's Laboratories, Inc. Bendamustine formulations
CA2819017A1 (en) * 2011-01-31 2012-08-09 Cephalon, Inc. Methods for the preparation of bendamustine
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US10905677B2 (en) 2016-08-31 2021-02-02 Navinta, Llc Bendamustine solution formulations
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CN111093654B (zh) * 2017-11-07 2023-03-10 江苏恒瑞医药股份有限公司 一种盐酸苯达莫司汀的晶体及其制备方法
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Also Published As

Publication number Publication date
US20170071913A1 (en) 2017-03-16
US20090264488A1 (en) 2009-10-22
CA2718939A1 (en) 2009-10-01
US8669279B2 (en) 2014-03-11
MX2010010398A (es) 2010-12-20
JP2011515472A (ja) 2011-05-19
WO2009120386A2 (en) 2009-10-01
US20140187598A1 (en) 2014-07-03
US8883836B2 (en) 2014-11-11
US20190015390A1 (en) 2019-01-17
WO2009120386A3 (en) 2009-12-03
CL2009000742A1 (es) 2009-11-13
US20160159748A1 (en) 2016-06-09
CN101980698A (zh) 2011-02-23
EP2271315B1 (en) 2016-09-14
US20130245086A1 (en) 2013-09-19
US10039750B2 (en) 2018-08-07
CN105693620A (zh) 2016-06-22
US20150051258A1 (en) 2015-02-19
US20200323824A1 (en) 2020-10-15
US8445524B2 (en) 2013-05-21
TW200944508A (en) 2009-11-01
EP3150197A1 (en) 2017-04-05
MX339878B (es) 2016-06-15
EP2271315A2 (en) 2011-01-12
CN103550159A (zh) 2014-02-05
CN103550159B (zh) 2016-02-10
ES2605205T3 (es) 2017-03-13
JP5536753B2 (ja) 2014-07-02
AR072777A1 (es) 2010-09-22
TWI472515B (zh) 2015-02-11
US20120071532A1 (en) 2012-03-22
US9533955B2 (en) 2017-01-03
CN101980698B (zh) 2013-10-16
US10517852B2 (en) 2019-12-31

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