MX339878B - Nuevas formas solidas de clorhidrato de bendamustina. - Google Patents

Nuevas formas solidas de clorhidrato de bendamustina.

Info

Publication number
MX339878B
MX339878B MX2013011045A MX2013011045A MX339878B MX 339878 B MX339878 B MX 339878B MX 2013011045 A MX2013011045 A MX 2013011045A MX 2013011045 A MX2013011045 A MX 2013011045A MX 339878 B MX339878 B MX 339878B
Authority
MX
Mexico
Prior art keywords
solid forms
novel solid
bendamustine hydrochloride
bendamustine
hydrochloride
Prior art date
Application number
MX2013011045A
Other languages
English (en)
Inventor
Martin Ian Cooper
Laurent D Courvoisier
Mark Eddleston
Robert E Mckean
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41051023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX339878(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MX339878B publication Critical patent/MX339878B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen nuevas formas sólidas de clorhidrato de bendamustina, al igual que métodos para su preparación y uso.
MX2013011045A 2008-03-26 2009-03-26 Nuevas formas solidas de clorhidrato de bendamustina. MX339878B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3975208P 2008-03-26 2008-03-26
PCT/US2009/001956 WO2009120386A2 (en) 2008-03-26 2009-03-26 Novel solid forms of bendamustine hydrochloride

Publications (1)

Publication Number Publication Date
MX339878B true MX339878B (es) 2016-06-15

Family

ID=41051023

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013011045A MX339878B (es) 2008-03-26 2009-03-26 Nuevas formas solidas de clorhidrato de bendamustina.
MX2010010398A MX2010010398A (es) 2008-03-26 2009-03-26 Nuevas formas solidas de clorhidrato de bendamustina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2010010398A MX2010010398A (es) 2008-03-26 2009-03-26 Nuevas formas solidas de clorhidrato de bendamustina.

Country Status (12)

Country Link
US (9) US20090264488A1 (es)
EP (2) EP2271315B1 (es)
JP (1) JP5536753B2 (es)
CN (3) CN105693620A (es)
AR (1) AR072777A1 (es)
CA (1) CA2718939A1 (es)
CL (1) CL2009000742A1 (es)
ES (1) ES2605205T3 (es)
HK (1) HK1220966A1 (es)
MX (2) MX339878B (es)
TW (1) TWI472515B (es)
WO (1) WO2009120386A2 (es)

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Also Published As

Publication number Publication date
US20150051258A1 (en) 2015-02-19
TWI472515B (zh) 2015-02-11
US20160159748A1 (en) 2016-06-09
MX2010010398A (es) 2010-12-20
EP2271315A2 (en) 2011-01-12
CN101980698A (zh) 2011-02-23
US20170071913A1 (en) 2017-03-16
TW200944508A (en) 2009-11-01
CN103550159B (zh) 2016-02-10
ES2605205T3 (es) 2017-03-13
CN103550159A (zh) 2014-02-05
US20140187598A1 (en) 2014-07-03
US10517852B2 (en) 2019-12-31
EP2271315B1 (en) 2016-09-14
AR072777A1 (es) 2010-09-22
US20090264488A1 (en) 2009-10-22
US20120071532A1 (en) 2012-03-22
US20200323824A1 (en) 2020-10-15
US8669279B2 (en) 2014-03-11
US20190015390A1 (en) 2019-01-17
WO2009120386A3 (en) 2009-12-03
US20130245086A1 (en) 2013-09-19
CA2718939A1 (en) 2009-10-01
CN105693620A (zh) 2016-06-22
CN101980698B (zh) 2013-10-16
US8445524B2 (en) 2013-05-21
EP3150197A1 (en) 2017-04-05
JP2011515472A (ja) 2011-05-19
CL2009000742A1 (es) 2009-11-13
JP5536753B2 (ja) 2014-07-02
US9533955B2 (en) 2017-01-03
US10039750B2 (en) 2018-08-07
US8883836B2 (en) 2014-11-11
WO2009120386A2 (en) 2009-10-01
HK1220966A1 (zh) 2017-05-19

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