HK1217718A1 - 向白細胞的有效轉運 - Google Patents

向白細胞的有效轉運

Info

Publication number
HK1217718A1
HK1217718A1 HK16105709.3A HK16105709A HK1217718A1 HK 1217718 A1 HK1217718 A1 HK 1217718A1 HK 16105709 A HK16105709 A HK 16105709A HK 1217718 A1 HK1217718 A1 HK 1217718A1
Authority
HK
Hong Kong
Prior art keywords
blood cells
white blood
efficient transport
efficient
transport
Prior art date
Application number
HK16105709.3A
Other languages
English (en)
Inventor
Christophe Bonny
Original Assignee
Xigen Inflammation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xigen Inflammation Ltd filed Critical Xigen Inflammation Ltd
Publication of HK1217718A1 publication Critical patent/HK1217718A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
HK16105709.3A 2008-12-22 2016-05-18 向白細胞的有效轉運 HK1217718A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2008/011003 WO2010072228A1 (en) 2008-12-22 2008-12-22 Novel transporter constructs and transporter cargo conjugate molecules
PCT/EP2009/003927 WO2010072275A1 (en) 2008-12-22 2009-06-02 Efficient delivery of medicaments into white blood cells

Publications (1)

Publication Number Publication Date
HK1217718A1 true HK1217718A1 (zh) 2017-01-20

Family

ID=41010878

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11113447.9A HK1159122A1 (zh) 2008-12-22 2011-12-13 高效轉運入白血細胞
HK16105709.3A HK1217718A1 (zh) 2008-12-22 2016-05-18 向白細胞的有效轉運

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK11113447.9A HK1159122A1 (zh) 2008-12-22 2011-12-13 高效轉運入白血細胞

Country Status (20)

Country Link
US (3) US20120142584A1 (zh)
EP (3) EP2361260B1 (zh)
JP (4) JP5777525B2 (zh)
CN (2) CN102256998B (zh)
AU (2) AU2009331922B2 (zh)
CA (2) CA2738989A1 (zh)
CY (1) CY1118243T1 (zh)
DK (2) DK2361259T3 (zh)
ES (1) ES2602785T3 (zh)
HK (2) HK1159122A1 (zh)
HR (1) HRP20161416T1 (zh)
HU (1) HUE030183T2 (zh)
LT (1) LT2361260T (zh)
PL (1) PL2361260T3 (zh)
PT (1) PT2361260T (zh)
RU (2) RU2558240C2 (zh)
SG (1) SG171707A1 (zh)
SI (1) SI2361260T1 (zh)
SM (1) SMT201700042B (zh)
WO (4) WO2010072228A1 (zh)

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WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2010072228A1 (en) * 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
CN102892783B (zh) * 2010-02-25 2016-11-09 杜克大学 诱导保护性抗hiv-1抗体的产生的方法
WO2011160653A1 (en) * 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
WO2012048721A1 (en) 2010-10-14 2012-04-19 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
CA2830259C (en) * 2011-03-18 2021-06-29 Duke University Peptides for suppressing inflammation
KR102183273B1 (ko) * 2011-05-05 2020-11-27 사렙타 쎄러퓨틱스, 인코퍼레이티드 펩타이드 올리고뉴클레오타이드 접합체
US9161948B2 (en) * 2011-05-05 2015-10-20 Sarepta Therapeutics, Inc. Peptide oligonucleotide conjugates
JP6113160B2 (ja) * 2011-07-19 2017-04-12 ヴィヴォスクリプト，インコーポレイテッド 軟骨損傷を修復するために遺伝子改変を伴わずに細胞を再プログラミングするための組成物および方法
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2013142167A1 (en) * 2012-03-20 2013-09-26 The University Of Iowa Research Foundation Gb virus c (hepatitis g virus) e2 glycoprotein as an immunomodulatory agent
AU2013343526B2 (en) 2012-11-08 2019-09-12 Phi Pharma Sa C4S proteoglycan specific transporter molecules
CN102993313A (zh) * 2012-12-14 2013-03-27 上海柯莱逊生物技术有限公司 一种gm-csf-tat-cea重组蛋白及其方法和应用
EP2934555B1 (en) * 2012-12-21 2021-09-22 Astellas Institute for Regenerative Medicine Methods for production of platelets from pluripotent stem cells
AU2014301631A1 (en) 2013-06-26 2015-08-27 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015038662A1 (en) * 2013-09-10 2015-03-19 The Texas A&M University System Compositions and methods for the delivery of molecules into live cells
CN103555729B (zh) * 2013-10-14 2016-08-24 成都华创生物技术有限公司 一种改造的trail基因序列、表达方法及应用
US9376490B2 (en) * 2014-04-01 2016-06-28 National Cheng Kung University Treatment of inflammatory pain using IL-20 antagonists
WO2015162285A1 (en) 2014-04-25 2015-10-29 Phi Pharma Sa C6s specific transporter molecules
WO2015162287A1 (en) 2014-04-25 2015-10-29 Phi Pharma Sa Keratan sulfate specific transporter molecules
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
US10342847B2 (en) 2015-02-27 2019-07-09 Vanderbilt University Compositions and methods for preventing and reducing inflammation and treating disorders associated with inflammation
GB2536650A (en) 2015-03-24 2016-09-28 Augmedics Ltd Method and system for combining video-based and optic-based augmented reality in a near eye display
CN105018499A (zh) * 2015-08-25 2015-11-04 武汉大学 一种抗乙型肝炎病毒的肽核酸及其用途
CN107428841B (zh) 2016-03-18 2021-06-11 凯尔格恩有限公司 非那雄胺和肽的结合物
KR20180132807A (ko) * 2016-04-07 2018-12-12 케이스 웨스턴 리저브 유니버시티 신경퇴행성 질환의 치료용 tdp-43 미토콘드리아 국소화 억제제
CN113150105B (zh) * 2016-07-04 2024-02-20 上海普佑生物医药有限公司 一种新型天然蛋白及其应用
JP7175887B2 (ja) 2016-11-09 2022-11-21 オハイオ・ステイト・イノベーション・ファウンデーション ジスルフィド含有細胞膜透過ペプチド並びにその製造方法及び使用方法
US11352394B2 (en) 2016-11-22 2022-06-07 Ohio State Innovation Foundation Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof
CN107226840A (zh) * 2017-05-04 2017-10-03 西安交通大学 一种细胞穿膜肽透皮吸收促进剂及其制备方法和应用
KR101943978B1 (ko) * 2017-12-28 2019-01-30 주식회사 하이센스바이오 신규한 펩타이드
WO2019211741A1 (en) 2018-05-02 2019-11-07 Augmedics Ltd. Registration of a fiducial marker for an augmented reality system
EP3790890A4 (en) 2018-05-09 2022-03-02 Ohio State Innovation Foundation CYCLIC PEPTIDES OF CELL PENETRATION WITH ONE OR MORE HYDROPHOBIC RESIDUES
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