LT2361260T - Nauji transporterių konstruktai ir transporterių kargo konjuguotosios molekulės - Google Patents

Nauji transporterių konstruktai ir transporterių kargo konjuguotosios molekulės

Info

Publication number
LT2361260T
LT2361260T LTEP09801170.3T LT09801170T LT2361260T LT 2361260 T LT2361260 T LT 2361260T LT 09801170 T LT09801170 T LT 09801170T LT 2361260 T LT2361260 T LT 2361260T
Authority
LT
Lithuania
Prior art keywords
transporter
novel
constructs
conjugate molecules
cargo conjugate
Prior art date
Application number
LTEP09801170.3T
Other languages
English (en)
Inventor
Christophe Bonny
Original Assignee
Xigen Inflammation Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xigen Inflammation Ltd. filed Critical Xigen Inflammation Ltd.
Publication of LT2361260T publication Critical patent/LT2361260T/lt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
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    • A61P31/22—Antivirals for DNA viruses for herpes viruses
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
LTEP09801170.3T 2008-12-22 2009-12-22 Nauji transporterių konstruktai ir transporterių kargo konjuguotosios molekulės LT2361260T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2008/011003 WO2010072228A1 (en) 2008-12-22 2008-12-22 Novel transporter constructs and transporter cargo conjugate molecules
PCT/EP2009/003927 WO2010072275A1 (en) 2008-12-22 2009-06-02 Efficient delivery of medicaments into white blood cells
PCT/EP2009/009229 WO2010072406A1 (en) 2008-12-22 2009-12-22 Novel transporter constructs and transporter cargo conjugate molecules

Publications (1)

Publication Number Publication Date
LT2361260T true LT2361260T (lt) 2016-10-25

Family

ID=41010878

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP09801170.3T LT2361260T (lt) 2008-12-22 2009-12-22 Nauji transporterių konstruktai ir transporterių kargo konjuguotosios molekulės

Country Status (20)

Country Link
US (3) US10023615B2 (lt)
EP (3) EP2361259B1 (lt)
JP (4) JP5711666B2 (lt)
CN (2) CN102256999B (lt)
AU (2) AU2009331922B2 (lt)
CA (2) CA2738989A1 (lt)
CY (1) CY1118243T1 (lt)
DK (2) DK2361260T3 (lt)
ES (1) ES2602785T3 (lt)
HK (2) HK1159122A1 (lt)
HR (1) HRP20161416T1 (lt)
HU (1) HUE030183T2 (lt)
LT (1) LT2361260T (lt)
PL (1) PL2361260T3 (lt)
PT (1) PT2361260T (lt)
RU (2) RU2570632C2 (lt)
SG (1) SG171707A1 (lt)
SI (1) SI2361260T1 (lt)
SM (1) SMT201700042B (lt)
WO (4) WO2010072228A1 (lt)

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JP2016523274A (ja) 2013-06-26 2016-08-08 ザイジェン インフラメーション リミテッド 種々の疾患を処置するためのｊｎｋシグナル伝達経路の新規の細胞透過性ペプチド阻害剤の使用
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KR20180132807A (ko) * 2016-04-07 2018-12-12 케이스 웨스턴 리저브 유니버시티 신경퇴행성 질환의 치료용 tdp-43 미토콘드리아 국소화 억제제
CN107573412B (zh) * 2016-07-04 2021-04-27 上海清流生物医药科技有限公司 一种新型天然蛋白及其应用
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CN108588046A (zh) * 2018-05-11 2018-09-28 武汉博百欧生物科技有限公司 从人体血液中性粒细胞嗜天青颗粒中制备天然髓过氧化物酶的方法
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