HK1213813A1 - 一种含埃克替尼的皮肤外用药物组合物及其应用 - Google Patents

一种含埃克替尼的皮肤外用药物组合物及其应用 Download PDF

Info

Publication number
HK1213813A1
HK1213813A1 HK16101922.3A HK16101922A HK1213813A1 HK 1213813 A1 HK1213813 A1 HK 1213813A1 HK 16101922 A HK16101922 A HK 16101922A HK 1213813 A1 HK1213813 A1 HK 1213813A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical composition
composition according
conmana
mass
skin
Prior art date
Application number
HK16101922.3A
Other languages
English (en)
Chinese (zh)
Inventor
王印祥
袁樹軍
袁树军
王燕萍
胡邵京
胡云雁
Original Assignee
贝达药业股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 贝达药业股份有限公司 filed Critical 贝达药业股份有限公司
Publication of HK1213813A1 publication Critical patent/HK1213813A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK16101922.3A 2013-10-11 2014-10-11 一种含埃克替尼的皮肤外用药物组合物及其应用 HK1213813A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2013/085042 2013-10-11
CN2013085042 2013-10-11
PCT/CN2014/088344 WO2015051763A1 (zh) 2013-10-11 2014-10-11 一种含埃克替尼的皮肤外用药物组合物及其应用

Publications (1)

Publication Number Publication Date
HK1213813A1 true HK1213813A1 (zh) 2016-07-15

Family

ID=52812537

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16101922.3A HK1213813A1 (zh) 2013-10-11 2014-10-11 一种含埃克替尼的皮肤外用药物组合物及其应用

Country Status (13)

Country Link
US (2) US20160235757A1 (https=)
EP (1) EP3056206A4 (https=)
JP (1) JP6463745B2 (https=)
AU (1) AU2014334222B2 (https=)
BR (1) BR112016007627A2 (https=)
CA (1) CA2926874C (https=)
HK (1) HK1213813A1 (https=)
IL (1) IL245015A0 (https=)
NZ (1) NZ718802A (https=)
RU (1) RU2698796C2 (https=)
SG (1) SG11201602826VA (https=)
TW (1) TWI630921B (https=)
WO (1) WO2015051763A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102270538B1 (ko) * 2013-06-09 2021-06-29 베타 파머수티컬 컴퍼니 리미티드 이코티닙 포스페이트의 신규한 다형체 형태 및 이의 용도
WO2022022434A1 (zh) * 2020-07-27 2022-02-03 杭州和正医药有限公司 含托法替尼药学上可接受的盐的药物组合物、制剂及应用
CN116829152A (zh) * 2021-02-02 2023-09-29 贝达药业股份有限公司 埃克替尼在非小细胞肺癌术后辅助治疗中的应用
CN116492293A (zh) * 2022-01-25 2023-07-28 杭州和正医药有限公司 一种含托法替尼的局部用药的药物组合物、制剂及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0618933A2 (pt) * 2005-11-24 2016-09-13 Basf Se método para produzir uma molécula efetora que se liga à queratina, molécula efetora que se liga à queratina, uso das moléculas efetoras que se ligam à queratina, composto, e, dermocosmético
FR2909284B1 (fr) * 2006-11-30 2012-09-21 Galderma Sa Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien
EP2392576B1 (en) 2008-07-08 2016-02-17 Beta Pharma, Inc. Icotinib hydrochloride, synthesis, crystallographic form, medical combination, and uses thereof
GB201010954D0 (en) * 2010-06-29 2010-08-11 Edko Pazarlama Tanitim Ticaret Compositions
MX2013004296A (es) * 2010-10-21 2013-09-26 Cadila Healthcare Ltd Composiciones farmaceuticas topicas que contienen gotas de tamaño nanometrico para el tratamiento de soriasis.

Also Published As

Publication number Publication date
EP3056206A4 (en) 2017-07-05
SG11201602826VA (en) 2016-05-30
JP6463745B2 (ja) 2019-02-06
IL245015A0 (en) 2016-05-31
WO2015051763A1 (zh) 2015-04-16
AU2014334222B2 (en) 2017-03-09
RU2698796C2 (ru) 2019-08-30
CA2926874A1 (en) 2015-04-16
CA2926874C (en) 2018-12-11
US20190321369A1 (en) 2019-10-24
AU2014334222A1 (en) 2016-05-05
NZ718802A (en) 2017-09-29
EP3056206A1 (en) 2016-08-17
TW201513894A (zh) 2015-04-16
RU2016118063A (ru) 2017-11-16
BR112016007627A2 (pt) 2017-08-01
JP2016532659A (ja) 2016-10-20
TWI630921B (zh) 2018-08-01
US20160235757A1 (en) 2016-08-18

Similar Documents

Publication Publication Date Title
CN101897691B (zh) 异硫氰酸酯类化合物在促进毛发生长中的应用
US20210113696A1 (en) Ionic liquid compositions for treatment of rosacea
CN116265017A (zh) 一种包含本维莫德和皮质类固醇的药物组合物
HK1213813A1 (zh) 一种含埃克替尼的皮肤外用药物组合物及其应用
CN101703468A (zh) 维生素e油纳米乳制剂与制备方法
CN104473865A (zh) 地奈德凝胶剂及其制备方法
JP6228351B2 (ja) 外用抗甲状腺軟膏の製造方法
CN109512779A (zh) 一种含埃克替尼的皮肤外用药物组合物及其应用
CN103126976A (zh) 一种盐酸特比萘芬乳膏及其制备方法
EP4509124A1 (en) Ruxolitinib composition and preparation method therefor
WO2024199216A1 (zh) 一种米诺地尔和芦可替尼的外用组合物及其用途
CN106668004A (zh) 依达拉奉和(+)2-莰醇搽剂及其制备方法
CN103127138B (zh) 含有保护剂的卤米松制剂及其制备方法
CN115227642A (zh) 甲硝唑凝胶制备工艺
KR20160061425A (ko) 이코티닙-함유 국소 피부 약학 조성물 및 이의 용도
CN110025615A (zh) 一种治疗炎症性皮肤病的药物、乳膏及其制备方法
CN104523711A (zh) 酮康他索乳膏及其制备方法
CN103142619B (zh) 一种治疗皮炎的药物组合物及其制备方法
CN102727425A (zh) 一种硝基咪唑类眼膏及其制备方法
HK40119928A (en) Ruxolitinib composition and preparation method therefor
CN109908074A (zh) 包括特比萘芬的外用剂组合物和其制备方法
DE60122827T2 (de) Wasserfreie topische Zubereitungen für die Haut
JP2001048785A (ja) ニトロイミダゾール系化合物を含むアトピー性皮膚炎治療用の外用剤
CN105769621A (zh) 一种温和祛痘化妆品组合物及其制备方法
CN114712382A (zh) 一种由几种中西药物结合组成的皮肤病药品