HK1211935A1 - New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors -(34-c)- - Google Patents

New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors -(34-c)-

Info

Publication number
HK1211935A1
HK1211935A1 HK15112840.0A HK15112840A HK1211935A1 HK 1211935 A1 HK1211935 A1 HK 1211935A1 HK 15112840 A HK15112840 A HK 15112840A HK 1211935 A1 HK1211935 A1 HK 1211935A1
Authority
HK
Hong Kong
Prior art keywords
pyrrolo
analogs
pyrrole derivatives
autotaxin inhibitors
octahydro
Prior art date
Application number
HK15112840.0A
Other languages
English (en)
Chinese (zh)
Inventor
熱羅姆．埃爾特
丹尼爾．洪齊格
帕特里齊奧．馬太
哈拉爾德．莫塞
唐國志
王利莎
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1211935A1 publication Critical patent/HK1211935A1/xx

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK15112840.0A 2013-03-12 2015-12-30 New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors -(34-c)- HK1211935A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13158724 2013-03-12
PCT/EP2014/054631 WO2014139978A1 (fr) 2013-03-12 2014-03-11 Nouveaux dérivés d'octahydro-pyrrolo [3,4-c]-pyrrole et analogues de ceux-ci servant d'inhibiteurs d'autotaxine

Publications (1)

Publication Number Publication Date
HK1211935A1 true HK1211935A1 (en) 2016-06-03

Family

ID=47843184

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112840.0A HK1211935A1 (en) 2013-03-12 2015-12-30 New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors -(34-c)-

Country Status (33)

Country Link
US (2) US20150376194A1 (fr)
EP (1) EP2970256B1 (fr)
JP (2) JP6483034B2 (fr)
KR (1) KR20150126036A (fr)
CN (1) CN105073748B (fr)
AR (1) AR095079A1 (fr)
AU (1) AU2014230943B8 (fr)
BR (1) BR112015022804A2 (fr)
CA (1) CA2901047A1 (fr)
CL (1) CL2015002386A1 (fr)
CR (1) CR20150436A (fr)
DK (1) DK2970256T3 (fr)
EA (1) EA035015B1 (fr)
ES (1) ES2763417T3 (fr)
HK (1) HK1211935A1 (fr)
HR (1) HRP20192274T1 (fr)
HU (1) HUE046776T2 (fr)
IL (1) IL240796B (fr)
LT (1) LT2970256T (fr)
MA (1) MA38432B1 (fr)
MX (1) MX2015011311A (fr)
MY (1) MY177574A (fr)
PE (1) PE20151605A1 (fr)
PH (1) PH12015501934B1 (fr)
PL (1) PL2970256T3 (fr)
PT (1) PT2970256T (fr)
RS (1) RS59682B1 (fr)
SG (1) SG11201507396YA (fr)
SI (1) SI2970256T1 (fr)
TW (1) TWI678368B (fr)
UA (1) UA115354C2 (fr)
WO (1) WO2014139978A1 (fr)
ZA (1) ZA201505944B (fr)

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