HK1211601A1 - A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor - Google Patents

A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor Download PDF

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Publication number
HK1211601A1
HK1211601A1 HK15112368.2A HK15112368A HK1211601A1 HK 1211601 A1 HK1211601 A1 HK 1211601A1 HK 15112368 A HK15112368 A HK 15112368A HK 1211601 A1 HK1211601 A1 HK 1211601A1
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herpes simplex
simplex virus
immune checkpoint
checkpoint inhibitor
treating melanoma
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HK15112368.2A
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English (en)
Chinese (zh)
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Ari VANDERWALDE
Mohamed SHABOOTI
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埃姆艮股份有限公司
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Application filed by 埃姆艮股份有限公司 filed Critical 埃姆艮股份有限公司
Publication of HK1211601A1 publication Critical patent/HK1211601A1/xx

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/763Herpes virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14311Parvovirus, e.g. minute virus of mice
    • C12N2750/14341Use of virus, viral particle or viral elements as a vector
    • C12N2750/14343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/025Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a parvovirus

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Biochemistry (AREA)
  • Epidemiology (AREA)
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  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
HK15112368.2A 2012-08-30 2013-08-30 A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor HK1211601A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261694963P 2012-08-30 2012-08-30
US61/694,963 2012-08-30
US201361846147P 2013-07-15 2013-07-15
US61/846,147 2013-07-15
PCT/US2013/057542 WO2014036412A2 (en) 2012-08-30 2013-08-30 A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor

Publications (1)

Publication Number Publication Date
HK1211601A1 true HK1211601A1 (en) 2016-05-27

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HK15112368.2A HK1211601A1 (en) 2012-08-30 2013-08-30 A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor

Country Status (13)

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US (2) US10034938B2 (OSRAM)
EP (3) EP3981791A1 (OSRAM)
JP (2) JP6457940B2 (OSRAM)
KR (2) KR20210008155A (OSRAM)
CN (2) CN114984062A (OSRAM)
AU (3) AU2013308595C1 (OSRAM)
CA (1) CA2881851C (OSRAM)
EA (1) EA201590451A1 (OSRAM)
ES (1) ES2871910T3 (OSRAM)
FI (1) FI3381942T4 (OSRAM)
HK (1) HK1211601A1 (OSRAM)
PT (1) PT3381942T (OSRAM)
WO (1) WO2014036412A2 (OSRAM)

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US20190060452A1 (en) 2019-02-28
CA2881851A1 (en) 2014-03-06
EP2890714A2 (en) 2015-07-08
AU2013308595C1 (en) 2019-01-17
CN104704002A (zh) 2015-06-10
EP3381942B2 (en) 2025-10-01
JP6457940B2 (ja) 2019-01-23
FI3381942T4 (fi) 2025-12-16
EA201590451A1 (ru) 2016-05-31
WO2014036412A2 (en) 2014-03-06
WO2014036412A3 (en) 2014-06-05
CA2881851C (en) 2021-01-26
CN104704002B (zh) 2022-05-10
US10034938B2 (en) 2018-07-31
KR20150047512A (ko) 2015-05-04
PT3381942T (pt) 2021-05-24
CN114984062A (zh) 2022-09-02
AU2013308595B2 (en) 2018-04-26
KR20210008155A (ko) 2021-01-20
AU2018208640A1 (en) 2018-08-09
JP2019065028A (ja) 2019-04-25
EP3381942A1 (en) 2018-10-03
JP2015526525A (ja) 2015-09-10
EP3381942B1 (en) 2021-04-14
US20150202290A1 (en) 2015-07-23
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EP3981791A1 (en) 2022-04-13

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