HK1210958A1 - Antibody drug conjugates (adc) that bind to 158p1d7 proteins 158p1d7 (adc) - Google Patents

Antibody drug conjugates (adc) that bind to 158p1d7 proteins 158p1d7 (adc)

Info

Publication number
HK1210958A1
HK1210958A1 HK15111836.8A HK15111836A HK1210958A1 HK 1210958 A1 HK1210958 A1 HK 1210958A1 HK 15111836 A HK15111836 A HK 15111836A HK 1210958 A1 HK1210958 A1 HK 1210958A1
Authority
HK
Hong Kong
Prior art keywords
adc
bind
proteins
drug conjugates
antibody drug
Prior art date
Application number
HK15111836.8A
Other languages
English (en)
Chinese (zh)
Inventor
Robert Kendall Morrison
Zili An
Karen Jane Meyrick Morrison
Josh Snyder
Xiao-Chi Jia
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agensys Inc filed Critical Agensys Inc
Publication of HK1210958A1 publication Critical patent/HK1210958A1/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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