HK1203932A1 - Heterocyclic amide derivatives as p2x7 receptor antagonists p2x7 - Google Patents
Heterocyclic amide derivatives as p2x7 receptor antagonists p2x7Info
- Publication number
- HK1203932A1 HK1203932A1 HK15104330.4A HK15104330A HK1203932A1 HK 1203932 A1 HK1203932 A1 HK 1203932A1 HK 15104330 A HK15104330 A HK 15104330A HK 1203932 A1 HK1203932 A1 HK 1203932A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- receptor antagonists
- amide derivatives
- heterocyclic amide
- heterocyclic
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2012050282 | 2012-01-20 | ||
PCT/IB2013/050479 WO2013108227A1 (en) | 2012-01-20 | 2013-01-18 | Heterocyclic amide derivatives as p2x7 receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1203932A1 true HK1203932A1 (en) | 2015-11-06 |
Family
ID=47757670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15104330.4A HK1203932A1 (en) | 2012-01-20 | 2015-05-07 | Heterocyclic amide derivatives as p2x7 receptor antagonists p2x7 |
Country Status (23)
Country | Link |
---|---|
US (1) | US9409917B2 (xx) |
EP (1) | EP2804865B1 (xx) |
JP (1) | JP6111268B2 (xx) |
KR (1) | KR102033190B1 (xx) |
CN (1) | CN104066737B (xx) |
AR (1) | AR089753A1 (xx) |
AU (1) | AU2013210682B2 (xx) |
BR (1) | BR112014017735B1 (xx) |
CA (1) | CA2863228C (xx) |
CL (1) | CL2014001772A1 (xx) |
EA (1) | EA024204B1 (xx) |
ES (1) | ES2563189T3 (xx) |
HK (1) | HK1203932A1 (xx) |
IL (1) | IL233662A0 (xx) |
MA (1) | MA35893B1 (xx) |
MX (1) | MX336247B (xx) |
NZ (1) | NZ628910A (xx) |
PH (1) | PH12014501415A1 (xx) |
PL (1) | PL2804865T3 (xx) |
SG (1) | SG11201403933UA (xx) |
TW (1) | TWI576347B (xx) |
WO (1) | WO2013108227A1 (xx) |
ZA (1) | ZA201406085B (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR087274A1 (es) | 2011-07-22 | 2014-03-12 | Actelion Pharmaceuticals Ltd | Derivados de amidas heterociclicas como antagonistas de receptores p2x7 |
CA2890886C (en) | 2012-12-12 | 2020-10-27 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
WO2014097140A1 (en) | 2012-12-18 | 2014-06-26 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
EP2956457B1 (en) | 2013-01-22 | 2016-11-23 | Actelion Pharmaceuticals Ltd | Heterocyclic amide derivatives as p2x7 receptor antagonists |
JP6282016B2 (ja) | 2013-01-22 | 2018-02-21 | イドーシア ファーマシューティカルズ リミテッドIdorsia Pharmaceuticals Ltd | P2x7受容体アンタゴニストとしての複素環アミド誘導体 |
BR112016021985B1 (pt) * | 2014-03-26 | 2022-08-30 | The General Hospital Corporation | Formulação farmacêutica |
EP3609868B1 (en) | 2017-03-13 | 2023-10-18 | RaQualia Pharma Inc. | Tetrahydroquinoline derivatives as p2x7 receptor antagonists |
UY38057A (es) | 2018-01-19 | 2019-08-30 | Cytokinetics Inc | Inhibidores de sarcómero cardíaco |
US11964967B2 (en) | 2018-06-26 | 2024-04-23 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
CN117083275A (zh) | 2021-03-04 | 2023-11-17 | 赛特凯恩蒂克公司 | 心脏肌节抑制剂 |
Family Cites Families (62)
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TR200102911T2 (tr) | 1999-04-09 | 2002-01-21 | Astrazeneca Ab | Adamantan türevleri. |
SE9904505D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Pharma Prod | Novel compounds |
TWI258462B (en) | 1999-12-17 | 2006-07-21 | Astrazeneca Ab | Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same |
GB0013737D0 (en) | 2000-06-07 | 2000-07-26 | Astrazeneca Ab | Novel compounds |
WO2003042190A1 (en) | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
PA8557501A1 (es) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
SE0103836D0 (sv) | 2001-11-16 | 2001-11-16 | Astrazeneca Ab | Novel compounds |
SE0200920D0 (sv) | 2002-03-25 | 2002-03-25 | Astrazeneca Ab | Novel compounds |
MXPA05007130A (es) | 2002-12-31 | 2005-08-26 | Pfizer Prod Inc | Inhibidores benzamida del receptor p2x7. |
PA8591801A1 (es) | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | Inhibidores benzamidicos del receptor p2x7. |
SE0300480D0 (sv) | 2003-02-21 | 2003-02-21 | Astrazeneca Ab | Novel compounds |
EP1626962B1 (en) | 2003-05-12 | 2007-02-28 | Pfizer Products Inc. | Benzamide inhibitors of the p2x7 receptor |
GB0312609D0 (en) | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
SE0302139D0 (sv) | 2003-07-28 | 2003-07-28 | Astrazeneca Ab | Novel compounds |
WO2005043407A1 (en) * | 2003-10-30 | 2005-05-12 | Koninklijke Philips Electronics N.V. | Method of predicting input |
MXPA06012595A (es) | 2004-04-29 | 2007-05-09 | Abbott Lab | Analogos de amino-tetrazoles y metodos de uso. |
SA05260265A (ar) | 2004-08-30 | 2005-12-03 | استرازينيكا ايه بي | مركبات جديدة |
SE0402925D0 (sv) | 2004-11-30 | 2004-11-30 | Astrazeneca Ab | Novel Compounds |
EP1844003A4 (en) | 2005-01-27 | 2010-09-22 | Astrazeneca Ab | NEW BIAROMATIC COMPOUNDS AS INHIBITORS OF THE P2X7 RECEPTOR |
ATE421518T1 (de) | 2005-02-10 | 2009-02-15 | Bristol Myers Squibb Co | Dihydrochinazolinone als 5ht-modulatoren |
US7297700B2 (en) | 2005-03-24 | 2007-11-20 | Renovis, Inc. | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof |
WO2007055374A1 (ja) * | 2005-11-14 | 2007-05-18 | Mitsubishi Tanabe Pharma Corporation | 骨粗鬆症治療剤 |
TWI464148B (zh) | 2006-03-16 | 2014-12-11 | Evotec Us Inc | 作為p2x7調節劑之雙環雜芳基化合物與其用途 |
CA2645652A1 (en) | 2006-03-16 | 2007-09-27 | Renovis, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
ES2569677T3 (es) | 2006-03-16 | 2016-05-12 | Second Genome, Inc. | Compuestos bicicloheteroarilo como moduladores de P2X7 y usos de los mismos |
US20100298285A1 (en) | 2006-03-16 | 2010-11-25 | Kelly Michael G | Biclycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof |
MX2008011919A (es) | 2006-03-16 | 2008-11-28 | Renovis Inc | Compuestos de bicicloheteroarilo como moduladores de p2x7 y usos de los mismos. |
US20100184802A1 (en) | 2006-03-16 | 2010-07-22 | Kelly Michael G | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof |
GB0611154D0 (en) | 2006-06-06 | 2006-07-19 | Glaxo Group Ltd | Novel receptor antagonists and their methods of use |
ATE489088T1 (de) | 2006-06-06 | 2010-12-15 | Glaxo Group Ltd | N- (phenylmethyl) -2- (1h-pyrazol-4-yl) acetamid- derivate als p2x7-antagonisten zur behandlung von schmerzen, entzündungen und neurodegeneration |
PL2049478T3 (pl) | 2006-07-06 | 2012-09-28 | Glaxo Group Ltd | Podstawione N-fenylometylo 5-okso-prolino-2-amidy jako antagoniści receptora P2X7 oraz sposoby ich zastosowania |
JP2010510987A (ja) | 2006-11-27 | 2010-04-08 | ハー・ルンドベック・アクチエゼルスカベット | ヘテロアリールアミド誘導体 |
TW200838516A (en) | 2007-01-31 | 2008-10-01 | Merck & Co Inc | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
EP2124562B1 (en) | 2007-03-09 | 2016-04-20 | Second Genome, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
PE20091225A1 (es) | 2007-03-22 | 2009-09-16 | Astrazeneca Ab | Derivados de quinolina como antagonistas del receptor p2x7 |
GB0705882D0 (en) | 2007-03-27 | 2007-05-02 | Glaxo Group Ltd | Novel compounds |
WO2008116845A1 (en) | 2007-03-28 | 2008-10-02 | Glaxo Group Limited | Piperidinone carboxamide derivatives as p2x7 modulators |
JP2010522710A (ja) | 2007-03-29 | 2010-07-08 | グラクソ グループ リミテッド | P2x7調節因子としてのオキサゾリジンおよびモルホリンカルボキサミド誘導体 |
KR20090127435A (ko) | 2007-04-03 | 2009-12-11 | 글락소 그룹 리미티드 | P2x7 조절제로서의 이미다졸리딘 카르복스아미드 유도체 |
EP2155744A1 (en) | 2007-04-10 | 2010-02-24 | Lundbeck, H., A/S | Heteroaryl amide analogues as p2x7 antagonists |
WO2008125600A2 (en) | 2007-04-11 | 2008-10-23 | Glaxo Group Limited | Pyrazole derivatives as p2x7 modulators |
DE602008005582D1 (de) | 2007-05-10 | 2011-04-28 | Glaxo Group Ltd | Pyrazolderivate als p2x7-modulatoren |
SI2178865T1 (sl) | 2007-07-19 | 2015-11-30 | Lundbeck, H., A/S | 5-členski heterociklični amidi in sorodne spojine |
WO2009023623A1 (en) * | 2007-08-10 | 2009-02-19 | H, Lundbeck A/S | Heteroaryl amide analogues |
PE20091036A1 (es) | 2007-11-30 | 2009-08-15 | Astrazeneca Ab | Derivado de quinolina como antagonista del receptor p2x7 |
GB0724258D0 (en) | 2007-12-12 | 2008-01-30 | Glaxo Group Ltd | Novel combinations |
WO2009074518A1 (en) | 2007-12-12 | 2009-06-18 | Glaxo Group Limited | Combinations of prolinamide p2x7 modulators with further therapeutic agents |
GB0724625D0 (en) | 2007-12-18 | 2008-01-30 | Glaxo Group Ltd | Novel compounds |
CA2709821A1 (en) | 2007-12-18 | 2009-06-25 | Glaxo Group Limited | 5-oxo-3-pyrrolidinecarboxamide derivatives as p2x7 modulators |
WO2009108551A2 (en) | 2008-02-25 | 2009-09-03 | H. Lundbeck A/S | Heteroaryl amide analogues |
BRPI0910034B1 (pt) | 2008-03-25 | 2022-02-08 | Affectis Pharmaceuticals Ag | Antagonistas do p2x7r e composições farmacêuticas que os compreendem |
EP2285800B1 (en) | 2008-04-22 | 2011-11-16 | Janssen Pharmaceutica, N.V. | Quinoline or isoquinoline substituted p2x7 antagonists |
EP2243772B1 (en) | 2009-04-14 | 2012-01-18 | Affectis Pharmaceuticals AG | Novel P2X7R antagonists and their use |
GB0919594D0 (en) | 2009-11-09 | 2009-12-23 | Glaxo Group Ltd | Compounds |
US20120157494A1 (en) | 2010-12-16 | 2012-06-21 | Harris Iii Ralph New | Isoindolyl compounds |
JP2014513671A (ja) | 2011-02-22 | 2014-06-05 | アクテリオン ファーマシューティカルズ リミテッド | P2x7受容体アンタゴニストとしてのベンズアミド誘導体 |
WO2012163792A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
AR087274A1 (es) * | 2011-07-22 | 2014-03-12 | Actelion Pharmaceuticals Ltd | Derivados de amidas heterociclicas como antagonistas de receptores p2x7 |
CA2890886C (en) | 2012-12-12 | 2020-10-27 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
WO2014097140A1 (en) | 2012-12-18 | 2014-06-26 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
JP6282016B2 (ja) | 2013-01-22 | 2018-02-21 | イドーシア ファーマシューティカルズ リミテッドIdorsia Pharmaceuticals Ltd | P2x7受容体アンタゴニストとしての複素環アミド誘導体 |
EP2956457B1 (en) | 2013-01-22 | 2016-11-23 | Actelion Pharmaceuticals Ltd | Heterocyclic amide derivatives as p2x7 receptor antagonists |
-
2013
- 2013-01-18 SG SG11201403933UA patent/SG11201403933UA/en unknown
- 2013-01-18 ES ES13707053.8T patent/ES2563189T3/es active Active
- 2013-01-18 AU AU2013210682A patent/AU2013210682B2/en not_active Ceased
- 2013-01-18 KR KR1020147022934A patent/KR102033190B1/ko active IP Right Grant
- 2013-01-18 BR BR112014017735-0A patent/BR112014017735B1/pt not_active IP Right Cessation
- 2013-01-18 EP EP13707053.8A patent/EP2804865B1/en active Active
- 2013-01-18 JP JP2014552736A patent/JP6111268B2/ja not_active Expired - Fee Related
- 2013-01-18 PL PL13707053T patent/PL2804865T3/pl unknown
- 2013-01-18 US US14/373,338 patent/US9409917B2/en active Active
- 2013-01-18 MX MX2014008736A patent/MX336247B/es unknown
- 2013-01-18 CN CN201380005966.8A patent/CN104066737B/zh not_active Expired - Fee Related
- 2013-01-18 EA EA201400822A patent/EA024204B1/ru not_active IP Right Cessation
- 2013-01-18 TW TW102102130A patent/TWI576347B/zh not_active IP Right Cessation
- 2013-01-18 WO PCT/IB2013/050479 patent/WO2013108227A1/en active Application Filing
- 2013-01-18 AR ARP130100155A patent/AR089753A1/es unknown
- 2013-01-18 NZ NZ628910A patent/NZ628910A/en not_active IP Right Cessation
- 2013-01-18 CA CA2863228A patent/CA2863228C/en active Active
-
2014
- 2014-06-20 PH PH12014501415A patent/PH12014501415A1/en unknown
- 2014-07-01 CL CL2014001772A patent/CL2014001772A1/es unknown
- 2014-07-16 IL IL233662A patent/IL233662A0/en unknown
- 2014-07-31 MA MA37252A patent/MA35893B1/fr unknown
- 2014-08-19 ZA ZA2014/06085A patent/ZA201406085B/en unknown
-
2015
- 2015-05-07 HK HK15104330.4A patent/HK1203932A1/xx unknown
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