HK1143810A1 - Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis - Google Patents

Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis

Info

Publication number
HK1143810A1
HK1143810A1 HK10110351.0A HK10110351A HK1143810A1 HK 1143810 A1 HK1143810 A1 HK 1143810A1 HK 10110351 A HK10110351 A HK 10110351A HK 1143810 A1 HK1143810 A1 HK 1143810A1
Authority
HK
Hong Kong
Prior art keywords
imidazo
hepatitis
treatment
viral infections
pyrazine compounds
Prior art date
Application number
HK10110351.0A
Other languages
English (en)
Inventor
Angus Macleod
Dale Robert Mitchell
Nicholas John Palmer
Christophe Claude Parsy
Michael Daniel Goldsmith
Clifford John Harris
Original Assignee
Biofocus Dpi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofocus Dpi Ltd filed Critical Biofocus Dpi Ltd
Publication of HK1143810A1 publication Critical patent/HK1143810A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK10110351.0A 2007-08-21 2010-11-04 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis HK1143810A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds
PCT/EP2008/060896 WO2009024585A2 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis

Publications (1)

Publication Number Publication Date
HK1143810A1 true HK1143810A1 (en) 2011-01-14

Family

ID=38566736

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10110351.0A HK1143810A1 (en) 2007-08-21 2010-11-04 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis

Country Status (21)

Country Link
US (1) US8362018B2 (xx)
EP (2) EP2567960A3 (xx)
JP (1) JP2010536825A (xx)
KR (1) KR20100081294A (xx)
CN (1) CN101835780B (xx)
AU (1) AU2008290531A1 (xx)
BR (1) BRPI0815717A2 (xx)
CA (1) CA2707521A1 (xx)
CY (1) CY1113872T1 (xx)
DK (1) DK2193131T3 (xx)
ES (1) ES2404415T3 (xx)
GB (1) GB0716292D0 (xx)
HK (1) HK1143810A1 (xx)
HR (1) HRP20130202T1 (xx)
MX (1) MX2010001733A (xx)
NZ (1) NZ584108A (xx)
PL (1) PL2193131T3 (xx)
PT (1) PT2193131E (xx)
SI (1) SI2193131T1 (xx)
WO (1) WO2009024585A2 (xx)
ZA (1) ZA201002009B (xx)

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AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
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WO2011137109A1 (en) 2010-04-30 2011-11-03 Boehringer Ingelheim International Gmbh Azaindazole amide compounds as ccr1 receptor antagonists
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JP5824065B2 (ja) * 2010-12-17 2015-11-25 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 過剰増殖性障害の治療におけるｍｐｓ−１およびｔｋｋ阻害剤として使用するための６置換イミダゾピラジン
US20130303532A1 (en) * 2010-12-17 2013-11-14 Bayer Intellectual Property Gmbh Imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment hyperproliferative disorders
EP2655371B1 (en) 2010-12-23 2015-02-25 Boehringer Ingelheim International GmbH Pyrazolopiperidine compounds as ccr1 receptor antagonists
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JPWO2013061962A1 (ja) * 2011-10-24 2015-04-02 武田薬品工業株式会社 二環性化合物
RU2657540C2 (ru) 2012-06-26 2018-06-14 Янссен Фармацевтика Нв Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств
AU2013289284B2 (en) 2012-07-09 2017-03-30 Janssen Pharmaceutica Nv Inhibitors of phosphodiesterase 10 enzyme
US9586949B2 (en) 2015-02-09 2017-03-07 Incyte Corporation Aza-heteroaryl compounds as PI3K-gamma inhibitors
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BR112017023038A2 (pt) * 2015-04-29 2018-07-03 Janssen Pharmaceutica Nv imidazopirazinas e pirazolopirimidinas e seu uso como moduladores do receptor ampa
RU2712196C2 (ru) * 2015-06-24 2020-01-24 Куровир Аб Производные пиразоло[1,5-a]триазин-4-амина, применимые в терапии
JP6507976B2 (ja) * 2015-09-30 2019-05-08 東レ株式会社 イミダゾール−２−カルボン酸エステル誘導体又はその塩の製造方法
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ES2833955T3 (es) 2016-01-05 2021-06-16 Incyte Corp Piridinas sustituidas con pirazol/imidazol como inhibidores de PI3K-Gamma
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WO2017223414A1 (en) * 2016-06-24 2017-12-28 Incyte Corporation HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
TW201817714A (zh) 2016-08-30 2018-05-16 英商葛蘭素史密斯克藍智慧財產權有限公司 抑制3c及3cl蛋白酶之化合物及其使用方法
EP4006034A1 (en) 2017-10-18 2022-06-01 Incyte Corporation Condensed imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors
AR114082A1 (es) 2018-01-17 2020-07-22 Glaxosmithkline Ip Dev Ltd INHIBIDORES DE LA PI4KIIIb
SG11202012616RA (en) 2018-08-21 2021-02-25 Kyorin Pharmaceutical Co Ltd Bicyclic heteroaromatic ring derivative
MA53561A (fr) 2018-09-05 2022-05-11 Incyte Corp Formes cristallines d'un inhibiteur de phosphoinositide 3-kinase (pi3k)
CN109369545B (zh) * 2018-12-14 2020-04-10 东营曜康医药科技有限公司 2-甲基-5-甲酸吡嗪的合成工艺
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CN113929633A (zh) * 2021-10-27 2022-01-14 山东大学 一种法匹拉韦的合成方法及其应用
CN113831255B (zh) * 2021-11-25 2022-03-11 山东诚创蓝海医药科技有限公司 一种2-氨基丙二酰胺的制备方法
CN115489188B (zh) * 2022-10-09 2023-08-29 安徽国风新材料股份有限公司 一种家居保护用聚酯薄膜及其制备方法

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Also Published As

Publication number Publication date
WO2009024585A2 (en) 2009-02-26
WO2009024585A3 (en) 2009-08-06
KR20100081294A (ko) 2010-07-14
AU2008290531A1 (en) 2009-02-26
US8362018B2 (en) 2013-01-29
CA2707521A1 (en) 2009-02-26
EP2567960A2 (en) 2013-03-13
BRPI0815717A2 (pt) 2015-02-10
MX2010001733A (es) 2010-07-06
PT2193131E (pt) 2013-04-04
EP2193131A2 (en) 2010-06-09
NZ584108A (en) 2012-06-29
DK2193131T3 (da) 2013-04-22
CN101835780B (zh) 2013-09-18
JP2010536825A (ja) 2010-12-02
SI2193131T1 (sl) 2013-06-28
US20110166147A1 (en) 2011-07-07
EP2193131B1 (en) 2013-01-30
GB0716292D0 (en) 2007-09-26
CN101835780A (zh) 2010-09-15
CY1113872T1 (el) 2016-07-27
ZA201002009B (en) 2010-12-29
HRP20130202T1 (hr) 2013-04-30
PL2193131T3 (pl) 2013-07-31
EP2567960A3 (en) 2013-06-05
ES2404415T3 (es) 2013-05-27

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170820