HK1120803A1 - Pyrazolo - Google Patents

Pyrazolo

Info

Publication number
HK1120803A1
HK1120803A1 HK09100008.1A HK09100008A HK1120803A1 HK 1120803 A1 HK1120803 A1 HK 1120803A1 HK 09100008 A HK09100008 A HK 09100008A HK 1120803 A1 HK1120803 A1 HK 1120803A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolo
Prior art date
Application number
HK09100008.1A
Other languages
English (en)
Inventor
Michael Brent Tollefson
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HK1120803A1 publication Critical patent/HK1120803A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
HK09100008.1A 2005-11-10 2009-01-02 Pyrazolo HK1120803A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73532005P 2005-11-10 2005-11-10
PCT/IB2006/003132 WO2007054778A1 (en) 2005-11-10 2006-10-31 Pyrazolo[4,3-d]pyrimidin-5-yl)derivative used as pde5 inhibitors

Publications (1)

Publication Number Publication Date
HK1120803A1 true HK1120803A1 (en) 2009-04-09

Family

ID=37685872

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09100008.1A HK1120803A1 (en) 2005-11-10 2009-01-02 Pyrazolo

Country Status (30)

Country Link
US (2) US20090156618A1 (no)
EP (1) EP1948661B1 (no)
JP (1) JP4208959B1 (no)
KR (1) KR101012592B1 (no)
CN (1) CN101305007B (no)
AP (1) AP2008004437A0 (no)
AR (1) AR057885A1 (no)
AT (1) ATE435865T1 (no)
AU (1) AU2006313486B2 (no)
BR (1) BRPI0618284A2 (no)
CA (1) CA2629339C (no)
CR (1) CR9966A (no)
DE (1) DE602006007728D1 (no)
DK (1) DK1948661T3 (no)
DO (1) DOP2006000248A (no)
EA (1) EA200800920A1 (no)
EC (1) ECSP088441A (no)
ES (1) ES2326919T3 (no)
HK (1) HK1120803A1 (no)
IL (1) IL190456A (no)
MA (1) MA29943B1 (no)
NL (1) NL2000291C2 (no)
NO (1) NO20082593L (no)
PE (1) PE20070764A1 (no)
RS (1) RS20080197A (no)
TN (1) TNSN08209A1 (no)
TW (1) TW200738723A (no)
UY (1) UY29909A1 (no)
WO (1) WO2007054778A1 (no)
ZA (1) ZA200803173B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2732628A1 (en) * 2008-08-01 2010-02-04 Biocryst Pharmaceuticals, Inc. Therapeutic agents
WO2010043633A1 (en) * 2008-10-15 2010-04-22 Palau Pharma, S. A. 2h-pyrazolo [4,3-d]pyrimidin-5-amine derivatives as h4 histamine receptor antagonists for the treatment of allergic, immunological and inflammatory diseases
EP2556820A4 (en) * 2010-04-05 2015-01-21 Sk Chemicals Co Ltd COMPOSITION CONTAINING PDE5 INHIBITOR FOR MITIGATION OF SKIN WRINKLES
US20140072557A1 (en) * 2011-02-28 2014-03-13 National Cerebral And Cardiovascular Center Medicinal agent for suppressing malignant tumor metastasis
US9802937B2 (en) 2011-04-21 2017-10-31 Origenis Gmbh Substituted pyrazolo{4,3-D}pyrimidines as kinase inhibitors
WO2014060112A1 (en) 2012-10-19 2014-04-24 Origenis Gmbh Pyrazolo[4,3-d]pyrimidines as kinase inhibitors
CA2888160A1 (en) * 2012-10-23 2014-05-01 Pfizer Inc. Use of a tetrasubstituted pyrazolo[4,3-d]pyrimidine compound for treating diabetic nephropathy
WO2016025100A2 (en) 2014-08-12 2016-02-18 Mezzion Pharma Co., Ltd. Methods of improving myocardial performance in fontan patients using udenafil compositions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998001428A1 (en) 1996-07-08 1998-01-15 Du Pont Pharmaceuticals Company AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN
JP3721077B2 (ja) 1998-04-20 2005-11-30 ファイザー・インク 性的不全を治療するためのピラゾロピリミジノンcGMPPDE5阻害剤
GB9822238D0 (en) * 1998-10-12 1998-12-09 Pfizer Ltd Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
ES2205945T3 (es) 1998-10-23 2004-05-01 Pfizer Inc. Pirazolopirimidinonas inhibidoras de gmpc pde5 para el tratamiento de disfunciones sexuales.
DE19942474A1 (de) 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine
CN1249051C (zh) 2000-04-28 2006-04-05 阿卡蒂亚药品公司 毒蕈碱性激动剂
DE10031584A1 (de) 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
WO2002016348A1 (en) 2000-08-09 2002-02-28 Astrazeneca Ab Antiangiogenic bicyclic derivatives
EP1348707B1 (en) 2002-03-28 2010-08-25 Ustav Experimentalni Botaniky AV CR, v.v.i. (Institute of Experimental Botany Academy of Sciences of the Czech Republic, PRO) Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy
RS20050810A (en) * 2003-04-29 2007-08-03 Pfizer Inc., 5,7-diaminopyrazolo(4,3-d)pyrimidines useful in the treatment of hypertension
NZ544040A (en) 2003-05-22 2009-03-31 Nycomed Gmbh Composition comprising a PDE4 inhibitor and a PDE5 inhibitor
AU2004289303A1 (en) 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
GB0327323D0 (en) * 2003-11-24 2003-12-31 Pfizer Ltd Novel pharmaceuticals
WO2005097799A1 (en) * 2004-04-07 2005-10-20 Pfizer Limited Pyrazolo`4,3-d! pyrimidines
CA2572331A1 (en) 2004-07-02 2006-02-09 Exelixis, Inc. C-met modulators and method of use
JP2008517994A (ja) * 2004-10-28 2008-05-29 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 新規医薬品

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IL190456A0 (en) 2008-11-03
AU2006313486A1 (en) 2007-05-18
JP4208959B1 (ja) 2009-01-14
AR057885A1 (es) 2007-12-26
CN101305007A (zh) 2008-11-12
ATE435865T1 (de) 2009-07-15
WO2007054778A1 (en) 2007-05-18
ECSP088441A (es) 2008-06-30
US20090156618A1 (en) 2009-06-18
RS20080197A (en) 2009-05-06
TW200738723A (en) 2007-10-16
EA200800920A1 (ru) 2008-10-30
PE20070764A1 (es) 2007-08-13
NL2000291A1 (nl) 2007-05-11
IL190456A (en) 2012-10-31
NL2000291C2 (nl) 2009-02-17
CR9966A (es) 2008-06-16
DE602006007728D1 (de) 2009-08-20
CN101305007B (zh) 2011-07-20
NO20082593L (no) 2008-07-22
TNSN08209A1 (fr) 2009-10-30
AU2006313486B2 (en) 2011-10-27
MA29943B1 (fr) 2008-11-03
DOP2006000248A (es) 2007-10-15
EP1948661B1 (en) 2009-07-08
ES2326919T3 (es) 2009-10-21
US20110059993A1 (en) 2011-03-10
BRPI0618284A2 (pt) 2011-08-23
EP1948661A1 (en) 2008-07-30
UY29909A1 (es) 2007-06-29
KR20080063830A (ko) 2008-07-07
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DK1948661T3 (da) 2009-09-07
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CA2629339A1 (en) 2007-05-18
ZA200803173B (en) 2009-01-28

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