HK1120803A1 - Pyrazolo - Google Patents

Pyrazolo

Info

Publication number
HK1120803A1
HK1120803A1 HK09100008.1A HK09100008A HK1120803A1 HK 1120803 A1 HK1120803 A1 HK 1120803A1 HK 09100008 A HK09100008 A HK 09100008A HK 1120803 A1 HK1120803 A1 HK 1120803A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolo
Prior art date
Application number
HK09100008.1A
Other languages
English (en)
Inventor
Michael Brent Tollefson
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HK1120803A1 publication Critical patent/HK1120803A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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HK09100008.1A 2005-11-10 2009-01-02 Pyrazolo HK1120803A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73532005P 2005-11-10 2005-11-10
PCT/IB2006/003132 WO2007054778A1 (en) 2005-11-10 2006-10-31 Pyrazolo[4,3-d]pyrimidin-5-yl)derivative used as pde5 inhibitors

Publications (1)

Publication Number Publication Date
HK1120803A1 true HK1120803A1 (en) 2009-04-09

Family

ID=37685872

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09100008.1A HK1120803A1 (en) 2005-11-10 2009-01-02 Pyrazolo

Country Status (30)

Country Link
US (2) US20090156618A1 (xx)
EP (1) EP1948661B1 (xx)
JP (1) JP4208959B1 (xx)
KR (1) KR101012592B1 (xx)
CN (1) CN101305007B (xx)
AP (1) AP2008004437A0 (xx)
AR (1) AR057885A1 (xx)
AT (1) ATE435865T1 (xx)
AU (1) AU2006313486B2 (xx)
BR (1) BRPI0618284A2 (xx)
CA (1) CA2629339C (xx)
CR (1) CR9966A (xx)
DE (1) DE602006007728D1 (xx)
DK (1) DK1948661T3 (xx)
DO (1) DOP2006000248A (xx)
EA (1) EA200800920A1 (xx)
EC (1) ECSP088441A (xx)
ES (1) ES2326919T3 (xx)
HK (1) HK1120803A1 (xx)
IL (1) IL190456A (xx)
MA (1) MA29943B1 (xx)
NL (1) NL2000291C2 (xx)
NO (1) NO20082593L (xx)
PE (1) PE20070764A1 (xx)
RS (1) RS20080197A (xx)
TN (1) TNSN08209A1 (xx)
TW (1) TW200738723A (xx)
UY (1) UY29909A1 (xx)
WO (1) WO2007054778A1 (xx)
ZA (1) ZA200803173B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010014930A2 (en) * 2008-08-01 2010-02-04 Biocryst Pharmaceuticals, Inc. Therapeutic agents
WO2010043633A1 (en) * 2008-10-15 2010-04-22 Palau Pharma, S. A. 2h-pyrazolo [4,3-d]pyrimidin-5-amine derivatives as h4 histamine receptor antagonists for the treatment of allergic, immunological and inflammatory diseases
CN102970965A (zh) * 2010-04-05 2013-03-13 Sk化学公司 含有pde5抑制剂的减少皮肤皱纹的合成物
WO2012118042A1 (ja) * 2011-02-28 2012-09-07 独立行政法人国立循環器病研究センター 悪性腫瘍転移抑制用医薬
TWI606049B (zh) 2011-04-21 2017-11-21 原真股份有限公司 新穎激酶抑制劑
US9637491B2 (en) 2012-10-19 2017-05-02 Origenis Gmbh Pyrazolo[4,3-D]pyrimidines as kinase inhibitors
CN104755086A (zh) * 2012-10-23 2015-07-01 辉瑞公司 四取代的吡唑并[4,3-d]嘧啶化合物用于治疗糖尿病肾病的用途
KR20170066334A (ko) 2014-08-12 2017-06-14 주식회사 메지온 유데나필 조성물을 이용하여 폰탄 환자에서 심근 성능을 개선시키는 방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0960102A1 (en) 1996-07-08 1999-12-01 Du Pont Pharmaceuticals Company AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN
HUP0102543A3 (en) 1998-04-20 2002-01-28 Pfizer Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
GB9822238D0 (en) * 1998-10-12 1998-12-09 Pfizer Ltd Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
BR9915532A (pt) 1998-10-23 2001-08-14 Pfizer Inibidores de cgmp pde5 de pirazolopirimidinona para tratamento da disfunção sexual
DE19942474A1 (de) 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine
US6627645B2 (en) 2000-04-28 2003-09-30 Acadia Pharmaceuticals, Inc. Muscarinic agonists
DE10031584A1 (de) 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
WO2002016348A1 (en) 2000-08-09 2002-02-28 Astrazeneca Ab Antiangiogenic bicyclic derivatives
DK1348707T3 (da) 2002-03-28 2010-12-13 Ustav Ex Botan Av Cr V V I Inst Of Ex Botany Academy Of Sciences Of The Czech Republic Pro Pyrazolo[4,3-d]pyrimidiner, fremgangsmåder til deres fremstilling samt deres terapeutiske anvendelse
WO2004096810A1 (en) * 2003-04-29 2004-11-11 Pfizer Limited 5,7-diaminopyrazolo`4,3-d!pyrimidines useful in the treatment of hypertension
WO2004103407A2 (en) 2003-05-22 2004-12-02 Altana Pharma Ag Composition comprising a pde4 inhibitor and a pde5 inhibitor
AU2004289303A1 (en) 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
GB0327323D0 (en) * 2003-11-24 2003-12-31 Pfizer Ltd Novel pharmaceuticals
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
WO2005097799A1 (en) * 2004-04-07 2005-10-20 Pfizer Limited Pyrazolo`4,3-d! pyrimidines
WO2006014325A2 (en) 2004-07-02 2006-02-09 Exelixis, Inc. C-met modulators and method of use
CA2585557C (en) * 2004-10-28 2009-08-18 Pharmacia & Upjohn Company Llc Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors

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JP4208959B1 (ja) 2009-01-14
ES2326919T3 (es) 2009-10-21
AU2006313486A1 (en) 2007-05-18
ATE435865T1 (de) 2009-07-15
AU2006313486B2 (en) 2011-10-27
TNSN08209A1 (fr) 2009-10-30
CR9966A (es) 2008-06-16
US20110059993A1 (en) 2011-03-10
MA29943B1 (fr) 2008-11-03
RS20080197A (xx) 2009-05-06
BRPI0618284A2 (pt) 2011-08-23
EA200800920A1 (ru) 2008-10-30
ECSP088441A (es) 2008-06-30
US20090156618A1 (en) 2009-06-18
CN101305007B (zh) 2011-07-20
PE20070764A1 (es) 2007-08-13
DOP2006000248A (es) 2007-10-15
US8518956B2 (en) 2013-08-27
NO20082593L (no) 2008-07-22
CN101305007A (zh) 2008-11-12
NL2000291A1 (nl) 2007-05-11
UY29909A1 (es) 2007-06-29
KR20080063830A (ko) 2008-07-07
AR057885A1 (es) 2007-12-26
DE602006007728D1 (de) 2009-08-20
AP2008004437A0 (en) 2008-04-30
EP1948661A1 (en) 2008-07-30
EP1948661B1 (en) 2009-07-08
CA2629339C (en) 2010-07-27
TW200738723A (en) 2007-10-16
ZA200803173B (en) 2009-01-28
IL190456A (en) 2012-10-31
CA2629339A1 (en) 2007-05-18
JP2009519215A (ja) 2009-05-14
KR101012592B1 (ko) 2011-02-07
WO2007054778A1 (en) 2007-05-18
IL190456A0 (en) 2008-11-03
NL2000291C2 (nl) 2009-02-17
DK1948661T3 (da) 2009-09-07

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