RS20080197A - Pyrazolo/4,3-d/pyrimidin-5-yl)derivative used as pde5 inhibitors - Google Patents
Pyrazolo/4,3-d/pyrimidin-5-yl)derivative used as pde5 inhibitorsInfo
- Publication number
- RS20080197A RS20080197A RSP-2008/0197A RSP20080197A RS20080197A RS 20080197 A RS20080197 A RS 20080197A RS P20080197 A RSP20080197 A RS P20080197A RS 20080197 A RS20080197 A RS 20080197A
- Authority
- RS
- Serbia
- Prior art keywords
- pyrazolo
- pyrimidin
- derivative used
- pde5 inhibitors
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract
Predmetni pronalazak se odnosi na (I) l-(l-(2-etoksietil)-3-etil-7-(4-metilpiridin- 2-ilamino)-l H-pirazolo[4,3-d|pirimidin-5-il)piperidin-4-karboksilnu kiselinu i njene soli. Pronalazak dalje obuhvata farmaceutske kompozicije, postupke lečenja i postupke siteze koji se odnose na Formulu (I). Formula (I) je upotrebljena za inhibiciju PDE5 enzima.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73532005P | 2005-11-10 | 2005-11-10 | |
PCT/IB2006/003132 WO2007054778A1 (en) | 2005-11-10 | 2006-10-31 | Pyrazolo[4,3-d]pyrimidin-5-yl)derivative used as pde5 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
RS20080197A true RS20080197A (en) | 2009-05-06 |
Family
ID=37685872
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2008/0197A RS20080197A (en) | 2005-11-10 | 2006-10-31 | Pyrazolo/4,3-d/pyrimidin-5-yl)derivative used as pde5 inhibitors |
Country Status (30)
Country | Link |
---|---|
US (2) | US20090156618A1 (sr) |
EP (1) | EP1948661B1 (sr) |
JP (1) | JP4208959B1 (sr) |
KR (1) | KR101012592B1 (sr) |
CN (1) | CN101305007B (sr) |
AP (1) | AP2008004437A0 (sr) |
AR (1) | AR057885A1 (sr) |
AT (1) | ATE435865T1 (sr) |
AU (1) | AU2006313486B2 (sr) |
BR (1) | BRPI0618284A2 (sr) |
CA (1) | CA2629339C (sr) |
CR (1) | CR9966A (sr) |
DE (1) | DE602006007728D1 (sr) |
DK (1) | DK1948661T3 (sr) |
DO (1) | DOP2006000248A (sr) |
EA (1) | EA200800920A1 (sr) |
EC (1) | ECSP088441A (sr) |
ES (1) | ES2326919T3 (sr) |
HK (1) | HK1120803A1 (sr) |
IL (1) | IL190456A (sr) |
MA (1) | MA29943B1 (sr) |
NL (1) | NL2000291C2 (sr) |
NO (1) | NO20082593L (sr) |
PE (1) | PE20070764A1 (sr) |
RS (1) | RS20080197A (sr) |
TN (1) | TNSN08209A1 (sr) |
TW (1) | TW200738723A (sr) |
UY (1) | UY29909A1 (sr) |
WO (1) | WO2007054778A1 (sr) |
ZA (1) | ZA200803173B (sr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2732628A1 (en) * | 2008-08-01 | 2010-02-04 | Biocryst Pharmaceuticals, Inc. | Therapeutic agents |
WO2010043633A1 (en) * | 2008-10-15 | 2010-04-22 | Palau Pharma, S. A. | 2h-pyrazolo [4,3-d]pyrimidin-5-amine derivatives as h4 histamine receptor antagonists for the treatment of allergic, immunological and inflammatory diseases |
WO2011126250A2 (ko) * | 2010-04-05 | 2011-10-13 | 에스케이케미칼 주식회사 | Pde5 억제제를 함유하는 피부 주름 개선용 조성물 |
WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
MX363696B (es) | 2011-04-21 | 2019-03-28 | Origenis Gmbh | Pirazolo[4,3-d]pirimidinas utiles como inhibidores de cinasas. |
WO2014060112A1 (en) | 2012-10-19 | 2014-04-24 | Origenis Gmbh | Pyrazolo[4,3-d]pyrimidines as kinase inhibitors |
CN104755086A (zh) * | 2012-10-23 | 2015-07-01 | 辉瑞公司 | 四取代的吡唑并[4,3-d]嘧啶化合物用于治疗糖尿病肾病的用途 |
KR20240122604A (ko) | 2014-08-12 | 2024-08-12 | 주식회사 메지온 | 유데나필 조성물을 이용하여 폰탄 환자에서 심근 성능을 개선시키는 방법 |
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JP2002514162A (ja) | 1996-07-08 | 2002-05-14 | デュポン ファーマシューティカルズ カンパニー | Xa因子阻害薬およびトロンビン阻害薬としてのアミジノインドール類、アミジノアゾール類、およびそれらの類似体 |
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TW200505900A (en) | 2000-04-28 | 2005-02-16 | Acadia Pharm Inc | Muscarinic agonists |
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