HK1109735A1 - Halogen-substituted boronophthalides for the treatment of infections - Google Patents

Halogen-substituted boronophthalides for the treatment of infections

Info

Publication number
HK1109735A1
HK1109735A1 HK08102801.7A HK08102801A HK1109735A1 HK 1109735 A1 HK1109735 A1 HK 1109735A1 HK 08102801 A HK08102801 A HK 08102801A HK 1109735 A1 HK1109735 A1 HK 1109735A1
Authority
HK
Hong Kong
Prior art keywords
boronophthalides
infections
halogen
substituted
treatment
Prior art date
Application number
HK08102801.7A
Other languages
English (en)
Inventor
Stephen J Baker
Tsutomu Akama
Carolyn Bellinger-Kawahara
Vincent S Hernandez
Karin M Hold
James J Leyden
Kirk R Maples
Jacob J Plattner
Virginia Sanders
Yong-Kang Zhang
Gregory Fieldson
Original Assignee
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36917059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1109735(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc
Publication of HK1109735A1 publication Critical patent/HK1109735A1/xx

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
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    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P27/00—Drugs for disorders of the senses
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
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    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK08102801.7A 2005-02-16 2008-03-11 Halogen-substituted boronophthalides for the treatment of infections HK1109735A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65406005P 2005-02-16 2005-02-16
PCT/US2006/005542 WO2006089067A2 (en) 2005-02-16 2006-02-16 Boron-containing small molecules

Publications (1)

Publication Number Publication Date
HK1109735A1 true HK1109735A1 (en) 2008-06-20

Family

ID=36917059

Family Applications (3)

Application Number Title Priority Date Filing Date
HK12100416.2A HK1160139A1 (en) 2005-02-16 2008-03-11 Biocidal boronophthalide compounds 2-[c]
HK08102801.7A HK1109735A1 (en) 2005-02-16 2008-03-11 Halogen-substituted boronophthalides for the treatment of infections
HK16110032.1A HK1221956A1 (zh) 2005-02-16 2016-08-23 用於治療感染的鹵代類苯酞化硼

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK12100416.2A HK1160139A1 (en) 2005-02-16 2008-03-11 Biocidal boronophthalide compounds 2-[c]

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16110032.1A HK1221956A1 (zh) 2005-02-16 2016-08-23 用於治療感染的鹵代類苯酞化硼

Country Status (26)

Country Link
US (11) US7582621B2 (el)
EP (4) EP3424932B1 (el)
JP (6) JP5038912B2 (el)
KR (4) KR101337068B1 (el)
CN (2) CN101160124A (el)
AU (3) AU2006214247C1 (el)
BR (1) BRPI0608431B8 (el)
CA (1) CA2597982C (el)
CY (3) CY1120695T1 (el)
DK (3) DK2987796T3 (el)
ES (4) ES2414095T3 (el)
FR (1) FR20C1024I2 (el)
HK (3) HK1160139A1 (el)
HU (4) HUE054365T2 (el)
IL (2) IL185080A (el)
LT (1) LTC2343304I2 (el)
LU (1) LUC00157I2 (el)
MX (1) MX369262B (el)
NL (1) NL301049I2 (el)
NZ (3) NZ560448A (el)
PL (4) PL2343304T3 (el)
PT (4) PT2343304E (el)
RU (3) RU2414906C2 (el)
SI (3) SI3424932T1 (el)
WO (1) WO2006089067A2 (el)
ZA (4) ZA200707408B (el)

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US8889656B2 (en) 2014-11-18
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ZA200905950B (en) 2010-11-24
MX369262B (es) 2019-11-04
US20100190748A1 (en) 2010-07-29
LTPA2020524I1 (lt) 2020-09-10
US20060234981A1 (en) 2006-10-19
DK2987796T3 (en) 2018-09-17
PT1853251E (pt) 2013-07-19
ES2872962T3 (es) 2021-11-03
PT2987796T (pt) 2018-10-18
FR20C1024I2 (fr) 2021-07-09
US20110319361A1 (en) 2011-12-29
FR20C1024I1 (el) 2020-07-31
HUE026021T2 (en) 2016-05-30
CN101160124A (zh) 2008-04-09
RU2414906C2 (ru) 2011-03-27
IL185080A (en) 2012-07-31
US20150065459A1 (en) 2015-03-05
JP2014132031A (ja) 2014-07-17
ZA201005380B (en) 2016-08-31
RU2007134429A (ru) 2009-03-27
SI2987796T1 (sl) 2018-11-30
US8039451B2 (en) 2011-10-18
KR20130100019A (ko) 2013-09-06
US20140142064A1 (en) 2014-05-22
EP2987796A1 (en) 2016-02-24
CY1124503T1 (el) 2022-07-22
HUE040060T2 (hu) 2019-02-28
AU2010203096C1 (en) 2012-09-20
JP2017105826A (ja) 2017-06-15
CY1120695T1 (el) 2019-12-11
WO2006089067A2 (en) 2006-08-24
US20190330245A1 (en) 2019-10-31
CY2020027I1 (el) 2021-01-27
AU2011200994A1 (en) 2011-03-31
SI3424932T1 (sl) 2021-08-31
KR20070112390A (ko) 2007-11-23
BRPI0608431B1 (pt) 2020-09-15
IL185080A0 (en) 2008-08-07
IL207156A (en) 2014-04-30
EP3424932B1 (en) 2021-04-07
PL2987796T3 (pl) 2018-12-31
ZA200707408B (en) 2009-11-25
KR20130095330A (ko) 2013-08-27
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HUS2000019I1 (hu) 2020-07-28
US8440642B2 (en) 2013-05-14
HUE054365T2 (hu) 2021-09-28
RU2606947C2 (ru) 2017-01-10
NZ560448A (en) 2009-08-28
BRPI0608431A2 (pt) 2009-12-29
NL301049I1 (nl) 2020-07-01
KR20100105869A (ko) 2010-09-30
NZ578297A (en) 2010-11-26
PT2343304E (pt) 2015-08-26
US20160108063A1 (en) 2016-04-21
LTC2343304I2 (lt) 2022-11-10
US20210070780A1 (en) 2021-03-11
LUC00157I2 (el) 2021-07-06
RU2016145916A3 (el) 2020-07-21
BRPI0608431B8 (pt) 2021-05-25
CA2597982C (en) 2014-07-08
RU2016145916A (ru) 2018-05-23
JP5038912B2 (ja) 2012-10-03

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