US20060148725A1
(en)
*
|
2001-12-21 |
2006-07-06 |
The Miriam Hospital |
Selective 11beta HSD inhibitors and methods of use thereof
|
AU2002361861A1
(en)
*
|
2001-12-21 |
2003-07-30 |
Rhode Island Hospital |
SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF
|
US7329683B2
(en)
|
2002-02-01 |
2008-02-12 |
Merck & Co., Inc. |
11-β-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
|
JO2397B1
(en)
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
PL377847A1
(pl)
|
2003-01-14 |
2006-02-20 |
Arena Pharmaceuticals Inc. |
1,2,3-Tripodstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie związanych z nim zaburzeń takich jak cukrzyca i hiperglikemia
|
EP1624876A2
(en)
*
|
2003-04-29 |
2006-02-15 |
The Miriam Hospital |
Selective testicular 11beta-hsd inhibitors and methods of use thereof
|
WO2004110375A2
(en)
*
|
2003-06-06 |
2004-12-23 |
Merck & Co., Inc. |
Combination therapy for the treatment of diabetes
|
GB0315111D0
(en)
|
2003-06-27 |
2003-07-30 |
Cancer Rec Tech Ltd |
Substituted 5-membered ring compounds and their use
|
CA2539741A1
(en)
|
2003-09-22 |
2005-03-31 |
Bionetworks Gmbh |
Prevention and treatment of inflammation-induced and/or immune-mediated bone loss
|
WO2005044192A2
(en)
|
2003-10-28 |
2005-05-19 |
Amgen Inc. |
Triazole compounds and uses related thereto
|
WO2005060694A2
(en)
*
|
2003-12-18 |
2005-07-07 |
Agy Therapeutics, Inc. |
Treatment of neurologic disorders with inhibitors of 11beta-hsd1
|
US7745630B2
(en)
|
2003-12-22 |
2010-06-29 |
Justin Stephen Bryans |
Triazolyl piperidine arginine vasopressin receptor modulators
|
CA2553345C
(en)
*
|
2004-01-26 |
2011-11-15 |
Merck & Co., Inc. |
Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1
|
US7354938B2
(en)
|
2004-03-23 |
2008-04-08 |
Amgen Inc. |
Pyrazole compounds and uses related thereto
|
CN1938286A
(zh)
*
|
2004-03-29 |
2007-03-28 |
默克公司 |
作为11-β-羟甾类脱氢酶-1抑制剂的二芳基三唑
|
US20050261302A1
(en)
*
|
2004-04-29 |
2005-11-24 |
Hoff Ethan D |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their therapeutic application
|
PL1747198T3
(pl)
*
|
2004-05-07 |
2008-11-28 |
Janssen Pharmaceutica Nv |
Pochodne adamantylopirolidyn-2-onu jako inhibitory 11ß-dehydrogenazy hydroksysteroidowej
|
TWI350168B
(en)
|
2004-05-07 |
2011-10-11 |
Incyte Corp |
Amido compounds and their use as pharmaceuticals
|
CA2565630C
(en)
|
2004-05-07 |
2013-05-28 |
Janssen Pharmaceutica N.V. |
Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
WO2005121132A1
(ja)
*
|
2004-06-11 |
2005-12-22 |
Shionogi & Co., Ltd. |
抗hcv作用を有する縮合ヘテロ環化合物
|
US20060025445A1
(en)
*
|
2004-08-02 |
2006-02-02 |
Xiang Jason S |
11-Beta HSD1 inhibitors
|
GB0418877D0
(en)
*
|
2004-08-24 |
2004-09-29 |
Univ Edinburgh |
Heart
|
DE602005017159D1
(de)
|
2004-08-30 |
2009-11-26 |
Janssen Pharmaceutica Nv |
Oxysteroid-dehydrogenase-inhibitoren
|
JP5208505B2
(ja)
|
2004-08-30 |
2013-06-12 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
11−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのn−2アダマンタニル−2−フェノキシ−アセトアミド誘導体
|
WO2006024628A1
(en)
|
2004-08-30 |
2006-03-09 |
Janssen Pharmaceutica N.V. |
Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
WO2006030805A1
(ja)
*
|
2004-09-16 |
2006-03-23 |
Astellas Pharma Inc. |
トリアゾール誘導体またはその塩
|
JP5140577B2
(ja)
|
2005-03-31 |
2013-02-06 |
タケダ カリフォルニア インコーポレイテッド |
ヒドロキシステロイドデヒドロゲナーゼ阻害剤
|
BRPI0610459A2
(pt)
|
2005-04-05 |
2010-06-22 |
Hoffmann La Roche |
composto, processo para a sua preparação, composições farmacêuticas que o compreendem, método para o tratamento terapêutico e/ou profilático de enfermidades que são moduladas por inibidores de deidrogenase de hidroxiesteróides-11b e utilização do composto
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
TW200716576A
(en)
*
|
2005-06-07 |
2007-05-01 |
Shionogi & Co |
Heterocyclic derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
US7579360B2
(en)
*
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US7572807B2
(en)
*
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
US7622492B2
(en)
|
2005-08-31 |
2009-11-24 |
Hoffmann-La Roche Inc. |
Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase
|
PL1942898T5
(pl)
|
2005-09-14 |
2014-10-31 |
Takeda Pharmaceuticals Co |
Inhibitory peptydazy dipeptydylowej do leczenia cukrzycy
|
CN102675221A
(zh)
|
2005-09-16 |
2012-09-19 |
武田药品工业株式会社 |
用于制备嘧啶二酮衍生物的方法中的中间体
|
RU2302066C1
(ru)
*
|
2005-09-22 |
2007-06-27 |
Научный центр волоконной оптики при Институте общей физики им. А.М. Прохорова Российской академии наук |
Волоконный световод для оптического усиления излучения на длине волны в диапазоне 1000-1700 нм, способы его изготовления и волоконный лазер
|
KR20080048502A
(ko)
|
2005-09-29 |
2008-06-02 |
머크 앤드 캄파니 인코포레이티드 |
멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
|
WO2007058346A1
(ja)
*
|
2005-11-21 |
2007-05-24 |
Shionogi & Co., Ltd. |
I型11βヒドロキシステロイド脱水素酵素阻害活性を有するヘテロ環化合物
|
WO2007084314A2
(en)
*
|
2006-01-12 |
2007-07-26 |
Incyte Corporation |
MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
|
WO2007082808A2
(en)
|
2006-01-18 |
2007-07-26 |
F. Hoffmann-La Roche Ag |
Thiazoles as 11 beta-hsd1 inhibitors
|
WO2007088895A1
(ja)
*
|
2006-01-31 |
2007-08-09 |
Mochida Pharmaceutical Co., Ltd. |
3-アリールアミノ-1,2,4-トリアゾール誘導体
|
US7834178B2
(en)
|
2006-03-01 |
2010-11-16 |
Bristol-Myers Squibb Company |
Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
|
BRPI0708782A2
(pt)
|
2006-03-16 |
2011-06-14 |
Astellas Pharma Inc |
derivado de triazol ou um sal deste
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
RU2009108280A
(ru)
|
2006-08-08 |
2010-09-20 |
Санофи-Авентис (Fr) |
Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение
|
DK2054049T3
(en)
|
2006-08-24 |
2016-08-01 |
Univ Tennessee Res Found |
SUBSTITUTED ACYLANILIDES AND PROCEDURES FOR USING THEREOF
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
WO2008039327A2
(en)
|
2006-09-22 |
2008-04-03 |
Merck & Co., Inc. |
Method of treatment using fatty acid synthesis inhibitors
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
TW200843794A
(en)
*
|
2006-12-21 |
2008-11-16 |
Centocor Inc |
Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
JP5319518B2
(ja)
|
2007-04-02 |
2013-10-16 |
Msd株式会社 |
インドールジオン誘導体
|
KR101376432B1
(ko)
|
2007-05-18 |
2014-05-16 |
시오노기세이야쿠가부시키가이샤 |
11β-하이드록시스테로이드 탈수소효소 유형 1 저해 활성을 갖는 질소-함유 헤테로환형 유도체
|
US8222417B2
(en)
|
2007-06-27 |
2012-07-17 |
Taisho Pharmaceutical Co., Ltd |
Compound having 11β-HSD1 inhibitory activity
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US8394823B2
(en)
*
|
2008-04-11 |
2013-03-12 |
Bristol-Myers Squibb Company |
Triazolopyridine compounds useful as DGAT1 inhibitors
|
WO2009126624A1
(en)
*
|
2008-04-11 |
2009-10-15 |
Bristol-Myers Squibb Company |
Triazolo compounds useful as dgat1 inhibitors
|
EP2298747B1
(en)
*
|
2008-07-03 |
2016-12-28 |
Astellas Pharma Inc. |
Triazole derivative or salt thereof
|
UY31968A
(es)
|
2008-07-09 |
2010-01-29 |
Sanofi Aventis |
Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
|
BRPI0919876A8
(pt)
|
2008-10-30 |
2016-02-10 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, uso de um composto, e, método para intensificar a qualidade do sono, para tratar insônia, e para tratar ou controlar obesidade em um paciente mamífero que necessita do mesmo.
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
AU2009314200B2
(en)
|
2008-11-17 |
2011-11-17 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic amines for the treatment of diabetes
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
KR20110119790A
(ko)
*
|
2009-02-12 |
2011-11-02 |
엑셀리시스, 인코포레이티드 |
당뇨병 및 비만을 치료하는데 tgr5 효능제로서 사용되는 트리아졸 및 이미다졸 유도체
|
ES2350077B1
(es)
|
2009-06-04 |
2011-11-04 |
Laboratorios Salvat, S.A. |
Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
US20120220567A1
(en)
|
2009-07-23 |
2012-08-30 |
Shipps Jr Gerald W |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
WO2011019538A1
(en)
|
2009-08-13 |
2011-02-17 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
SG178880A1
(en)
|
2009-08-26 |
2012-04-27 |
Sanofi Sa |
Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
|
RU2550508C2
(ru)
|
2009-09-02 |
2015-05-10 |
Мерк Шарп И Доум Корп. |
Аминотетрагидропираны в качестве ингибиторов дипептидилпептидазы-iv для лечения или предупреждения диабета
|
EP2509997B1
(en)
|
2009-12-07 |
2017-08-30 |
i2 Pharmaceuticals, Inc. |
Conjugates comprising an antibody surrogate scaffold with improved pharmacokinetic properties
|
US8846739B2
(en)
*
|
2009-12-11 |
2014-09-30 |
Exelixis Patent Company Llc |
TGR5 agonists
|
EP2538783B1
(en)
|
2010-02-22 |
2016-06-01 |
Merck Sharp & Dohme Corp. |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
WO2011146358A1
(en)
|
2010-05-21 |
2011-11-24 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
WO2011157827A1
(de)
|
2010-06-18 |
2011-12-22 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
US8742110B2
(en)
|
2010-08-18 |
2014-06-03 |
Merck Sharp & Dohme Corp. |
Spiroxazolidinone compounds
|
UA112418C2
(uk)
|
2010-09-07 |
2016-09-12 |
Астеллас Фарма Інк. |
Терапевтичний болезаспокійливий засіб
|
BR112013008100A2
(pt)
|
2010-09-22 |
2016-08-09 |
Arena Pharm Inc |
"moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
|
US8828995B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
WO2012120052A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
US8809324B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
WO2012120057A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
US8846666B2
(en)
|
2011-03-08 |
2014-09-30 |
Sanofi |
Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2693882B1
(en)
|
2011-04-08 |
2017-06-28 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
JP5901025B2
(ja)
*
|
2011-04-19 |
2016-04-06 |
第一三共株式会社 |
テトラヒドロチアゼピン誘導体
|
CA2837517A1
(en)
|
2011-06-02 |
2012-12-06 |
Intervet International B.V. |
Imidazole derivatives
|
EP2720544B1
(en)
|
2011-06-16 |
2016-12-21 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
EP2760862B1
(en)
|
2011-09-27 |
2015-10-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
WO2013048916A1
(en)
|
2011-09-30 |
2013-04-04 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
US9018200B2
(en)
|
2011-10-24 |
2015-04-28 |
Merck Sharp & Dohme Corp. |
Substituted piperidinyl compounds useful as GPR119 agonists
|
WO2013068328A1
(en)
|
2011-11-07 |
2013-05-16 |
Intervet International B.V. |
Bicyclo [2.2.2] octan-1-ylcarboxylic acid compounds as dgat-1 inhibitors
|
WO2013068439A1
(en)
|
2011-11-09 |
2013-05-16 |
Intervet International B.V. |
4-amino-5-oxo-7,8-dihydropyrimido[5, 4 -f] [1, 4] oxazepine compounds as dgat1 inhibitors
|
CA2855009C
(en)
|
2011-11-15 |
2019-07-09 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds useful as gpr119 agonists
|
US9073930B2
(en)
|
2012-02-17 |
2015-07-07 |
Merck Sharp & Dohme |
Dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
JP2015519309A
(ja)
|
2012-04-16 |
2015-07-09 |
カネック ファーマ インコーポレイテッド |
Ptp−1bインヒビター前駆体としての縮合芳香族ホスホナート誘導体
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
KR102238970B1
(ko)
|
2012-07-13 |
2021-04-09 |
지티엑스, 인코포레이티드 |
선택적 안드로겐 수용체 조절자(sarms)를 이용한 안드로겐 수용체(ar) 양성 유방암의 치료 방법
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
WO2014018350A1
(en)
|
2012-07-23 |
2014-01-30 |
Merck Sharp & Dohme Corp. |
Treating diabetes with dipeptidyl peptidase-iv inhibitors
|
JP2015525782A
(ja)
|
2012-08-02 |
2015-09-07 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
抗糖尿病性三環式化合物
|
EP2931734B1
(en)
|
2012-12-17 |
2020-12-02 |
Merck Sharp & Dohme Corp. |
Novel glucokinase activator compounds, compositions containing such compounds, and methods of treatment
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015089809A1
(en)
|
2013-12-19 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Antidiabetic substituted heteroaryl compounds
|
WO2015112465A1
(en)
|
2014-01-24 |
2015-07-30 |
Merck Sharp & Dohme Corp. |
Isoquinoline derivatives as mgat2 inhibitors
|
WO2015176267A1
(en)
|
2014-05-22 |
2015-11-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
JP6553094B2
(ja)
*
|
2014-06-12 |
2019-07-31 |
ユニヴェルシテ・ドゥ・リール・2・ドロワ・エ・サンテ |
イミダゾール−または1,2,4−トリアゾール−誘導体及びその使用
|
US10968193B2
(en)
|
2014-08-08 |
2021-04-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2016022446A1
(en)
|
2014-08-08 |
2016-02-11 |
Merck Sharp & Dohme Corp. |
[5,6]-fused bicyclic antidiabetic compounds
|
US10662171B2
(en)
|
2014-08-08 |
2020-05-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
MD20170055A2
(ro)
|
2014-10-24 |
2017-09-30 |
Merck Sharp & Dohme Corp |
Co-agonişti ai receptorilor glucagonului şi GLP-1
|
US9920118B2
(en)
|
2014-10-31 |
2018-03-20 |
Ngm Biopharmaceuticals, Inc. |
Compositions and methods of use for treating metabolic disorders
|
TW201625635A
(zh)
|
2014-11-21 |
2016-07-16 |
默沙東藥廠 |
作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物
|
AU2016205361C1
(en)
|
2015-01-06 |
2021-04-08 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the S1P1 receptor
|
EP3303342B1
(en)
|
2015-05-27 |
2021-03-17 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
US10213429B2
(en)
|
2015-05-28 |
2019-02-26 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
SI3310760T1
(sl)
|
2015-06-22 |
2023-02-28 |
Arena Pharmaceuticals, Inc. |
Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1
|
US10800826B2
(en)
|
2015-10-05 |
2020-10-13 |
Merck Sharp & Dohme Corp. |
Antibody peptide conjugates that have agonist activity at both the glucagon and glucagon-like peptide 1 receptors
|
WO2017107052A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase stimulators
|
EP3235813A1
(en)
|
2016-04-19 |
2017-10-25 |
Cidqo 2012, S.L. |
Aza-tetra-cyclo derivatives
|
WO2017197555A1
(en)
|
2016-05-16 |
2017-11-23 |
Merck Sharp & Dohme Corp. |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
|
WO2017201683A1
(en)
|
2016-05-25 |
2017-11-30 |
Merck Sharp & Dohme Corp. |
Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists
|
EP3496715B1
(en)
|
2016-08-15 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
WO2018034918A1
(en)
|
2016-08-15 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
EP3515891B1
(en)
|
2016-09-20 |
2023-03-08 |
Merck Sharp & Dohme LLC |
Substituted 1-methyl-1,2,3,4-tetrahydroisoquinoline molecules as pcsk9 allosteric binders
|
RU2019117958A
(ru)
|
2016-11-18 |
2020-12-18 |
Мерк Шарп И Доум Корп. |
Производные индола, полезные в качестве ингибиторов диацилглицерид-о-ацилтрансферазы 2
|
WO2018107415A1
(en)
|
2016-12-15 |
2018-06-21 |
Merck Sharp & Dohme Corp. |
Hydroxy isoxazole compounds useful as gpr120 agonists
|
KR20190116416A
(ko)
|
2017-02-16 |
2019-10-14 |
아레나 파마슈티칼스, 인크. |
원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
|
JOP20190150A1
(ar)
|
2018-06-21 |
2019-12-21 |
Merck Sharp & Dohme |
مركبات مناهضة لـ pcsk9
|
WO2020167706A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
US20220177465A1
(en)
|
2019-04-04 |
2022-06-09 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
WO2021041770A1
(en)
|
2019-08-30 |
2021-03-04 |
Merck Sharp & Dohme Corp. |
Pcsk9 antagonist compounds
|
EP3842449A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled olefin co-agonists of the glucagon and glp-1 receptors
|
EP3842061A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled triazole co-agonists of the glucagon and glp-1 receptors
|
EP3842060A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled lactam co-agonists of the glucagon and glp-1 receptors
|
EP4153584A1
(en)
|
2020-05-18 |
2023-03-29 |
Merck Sharp & Dohme LLC |
Novel diacylglyceride o-acyltransferase 2 inhibitors
|
US20230365533A1
(en)
|
2020-08-18 |
2023-11-16 |
Merck Sharp & Dohme Llc |
Bicycloheptane pyrrolidine orexin receptor agonists
|
KR102445638B1
(ko)
|
2020-09-03 |
2022-09-20 |
충남대학교산학협력단 |
11 알파 하이드록시프로게스테론을 포함하는 당뇨병 예방 또는 치료용 조성물
|
CR20230159A
(es)
|
2020-10-08 |
2023-06-02 |
Merck Sharp & Dohme Llc |
Preparación de derivados de benzoimidazolona como nuevos inhibidores de la diacilglicerol o-aciltransferasa 2
|
EP4387645A1
(en)
|
2021-08-19 |
2024-06-26 |
Merck Sharp & Dohme LLC |
Compounds for treating conditions related to pcsk9 activity
|
CN116003279B
(zh)
*
|
2022-06-13 |
2024-05-28 |
苏州大学 |
一种绿色的n-甲基酰胺化合物的制备方法
|
TW202404574A
(zh)
|
2022-06-15 |
2024-02-01 |
美商默沙東有限責任公司 |
用於捕捉介白素-1 β之環狀肽
|
WO2024118858A1
(en)
|
2022-12-02 |
2024-06-06 |
Merck Sharp & Dohme Llc |
Preparation of fused azole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors
|