HK1077808A1 - 四氟芐衍生物及內含同類項目以預防和治療中樞神經系統中急性與慢性神經退化疾病的醫藥成份 - Google Patents
四氟芐衍生物及內含同類項目以預防和治療中樞神經系統中急性與慢性神經退化疾病的醫藥成份Info
- Publication number
- HK1077808A1 HK1077808A1 HK06100367.9A HK06100367A HK1077808A1 HK 1077808 A1 HK1077808 A1 HK 1077808A1 HK 06100367 A HK06100367 A HK 06100367A HK 1077808 A1 HK1077808 A1 HK 1077808A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preventing
- pharmaceutical composition
- nervous system
- central nervous
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C215/76—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/49—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20020034259 | 2002-06-19 | ||
PCT/KR2003/001205 WO2004000786A1 (en) | 2002-06-19 | 2003-06-19 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1077808A1 true HK1077808A1 (zh) | 2006-02-24 |
Family
ID=29997360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06100367.9A HK1077808A1 (zh) | 2002-06-19 | 2006-01-10 | 四氟芐衍生物及內含同類項目以預防和治療中樞神經系統中急性與慢性神經退化疾病的醫藥成份 |
Country Status (11)
Country | Link |
---|---|
US (5) | US6927303B2 (zh) |
EP (1) | EP1551793B1 (zh) |
JP (1) | JP4113957B2 (zh) |
KR (2) | KR100545745B1 (zh) |
CN (2) | CN101041626B (zh) |
AU (1) | AU2003245070C1 (zh) |
CA (1) | CA2490120C (zh) |
DK (1) | DK1551793T3 (zh) |
ES (1) | ES2568491T3 (zh) |
HK (1) | HK1077808A1 (zh) |
WO (1) | WO2004000786A1 (zh) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101041626B (zh) * | 2002-06-19 | 2010-08-25 | 艾克尔制药公司 | 四氟苄基衍生物及含有其成分的药物组合物 |
WO2006126825A1 (en) * | 2005-05-23 | 2006-11-30 | Choongwae Pharma Corporation | Composition comprising tetrafluorobenzyl derivatives or salts of thereof for injection |
RU2413715C2 (ru) * | 2005-05-25 | 2011-03-10 | Чунгвей Фарма Корпорейшн | Способ получения замещенных тетрафторбензиланилиновых соединений и их фармацевтически приемлемых солей |
KR100668111B1 (ko) * | 2005-07-28 | 2007-01-12 | (주)에스에이치제약 | 강력한 항산화 효과를 가짐으로써 급성 및 퇴행성 뇌신경계질환의 예방 및 치료에 이용 가능한 신규물질인아미노살리실산 유도체와 그 염의 제조방법 |
JP5208369B2 (ja) * | 2005-08-24 | 2013-06-12 | ニューロテック ファーマシューティカルズ カンパニー リミテッド | 神経細胞の死滅または神経機能の障害を治療するための薬学製剤及び併用療法 |
US20070049565A1 (en) * | 2005-08-24 | 2007-03-01 | Neurotech Pharmaceuticals Co., Ltd. | Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction |
US20070298129A1 (en) * | 2005-08-24 | 2007-12-27 | Neurotech Pharmaceuticals Co., Ltd. | Compounds and compositions for treating neuronal death or neurological dysfunction |
JP5450053B2 (ja) | 2006-04-13 | 2014-03-26 | ニューロテック ファーマシューティカルズ カンパニー リミテッド | 細胞損傷及び炎症疾患の治療または予防用薬学組成物 |
BRPI0712812A2 (pt) * | 2006-05-26 | 2012-10-23 | Phenomenome Discoveries Inc | biomarcadores úteis para diagnosticar esclerose múltipla e outras desordens e seus metodos |
KR101047387B1 (ko) * | 2007-10-05 | 2011-07-08 | (주)에스에이치제약 | 뇌신경 보호를 위한 병용요법 |
AU2008319397B2 (en) | 2007-11-01 | 2013-01-31 | Acucela, Inc. | Amine derivative compounds for treating ophthalmic diseases and disorders |
KR100852962B1 (ko) * | 2007-11-12 | 2008-08-20 | 주식회사 뉴로테크 | 2-하이드록시-5-페닐알킬아미노벤조산 유도체 및 이의 염의제조방법 |
AR069501A1 (es) | 2007-11-30 | 2010-01-27 | Genentech Inc | Anticuerpos anti- vegf (factor de crecimiento endotelial vascular) |
KR101523345B1 (ko) * | 2008-04-28 | 2015-05-28 | 주식회사 지엔티파마 | 재관류 손상의 치료 또는 예방용 약학 조성물 |
US9101645B2 (en) | 2008-10-22 | 2015-08-11 | Genentech, Inc. | Modulation of axon degeneration |
KR101204108B1 (ko) * | 2009-02-09 | 2012-11-22 | 주식회사 지엔티파마 | 5-벤질아미노살리실산 유도체 또는 이의 염의 의약 용도 |
ES2633691T3 (es) * | 2009-04-06 | 2017-09-22 | Neurotech Pharmaceuticals Co., Ltd. | Composición farmacéutica para tratar o prevenir lesiones por quemaduras |
ITMI20111288A1 (it) * | 2011-07-11 | 2013-01-12 | Chemi Spa | Precursore farmaceutico di un principio attivo antiinfiammatorio |
CN102617383A (zh) * | 2012-03-20 | 2012-08-01 | 横店集团家园化工有限公司 | 索法地尔晶型、制备方法及包含索法地尔晶体的无菌粉末 |
CN104817465B (zh) * | 2015-04-03 | 2016-10-05 | 浙江普洛医药科技有限公司 | 索法地尔杂质a及其制备方法和应用 |
CN109562089A (zh) * | 2016-06-13 | 2019-04-02 | 心悦生医股份有限公司 | 苯甲酸锂用于治疗中枢神经系统疾病的用途 |
CN106831462B (zh) * | 2016-12-30 | 2018-08-21 | 浙江普洛家园药业有限公司 | 索法地尔杂质b及其制备方法和应用 |
CN108164431B (zh) * | 2018-01-12 | 2021-10-08 | 浙江普洛家园药业有限公司 | 2-羟基-5-(2,3,5,6-四氟-4-三氟甲基苄氨基)苯甲酸及其制备方法 |
WO2020136441A1 (en) * | 2018-12-28 | 2020-07-02 | Gnt Pharma Co., Ltd. | Compositions and methods for treating neurodegenerative disorders |
EP4117648A1 (en) | 2020-03-11 | 2023-01-18 | GNT Pharma Co., Ltd | Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy |
CN113995723A (zh) | 2020-07-27 | 2022-02-01 | 浙江普洛家园药业有限公司 | 一种索法地尔冻干粉针剂的制备方法及其产品和用途 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7008623A (zh) | 1969-06-25 | 1970-12-29 | ||
US3632760A (en) * | 1969-06-25 | 1972-01-04 | Merck & Co Inc | Treatment of inflammation |
US3674844A (en) * | 1970-04-20 | 1972-07-04 | Merck & Co Inc | Salicylic acid derivatives |
JPS6056130B2 (ja) | 1978-03-20 | 1985-12-09 | 久光製薬株式会社 | 新規なサリチル酸誘導体 |
DK117484A (da) | 1983-03-14 | 1984-09-15 | Carpibem | 1-(2-carbethoxy-4-benzalkylamido-phenoxy)-3-amino-2-propanoler og fremgangsmaade til fremstilling deraf samt forbindelsernes anvendelse som laegemidler |
JPS60237041A (ja) | 1984-03-02 | 1985-11-25 | Yamamoto Kagaku Kogyo Kk | 3−プロピオニルサリチル酸誘導体の製造法 |
IT1196348B (it) | 1984-11-29 | 1988-11-16 | Italfarmaco Spa | Composti ad attivita'antiinfiammatoria |
FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
CA2150123C (en) | 1992-12-10 | 2004-12-07 | Harry R. Howard | Aminomethylene substituted non-aromatic heterocycles |
US5434163A (en) * | 1993-05-14 | 1995-07-18 | The Medical College Of Pennsylvania | Treatment of Cryptococcus neoformans infection |
DE69836378T2 (de) * | 1997-07-01 | 2007-10-11 | Warner-Lambert Co. Llc | Benzoesäure- und Benzamid-Derivate von Anthranilsäure und ihre Anwendung als MEK-Inhibitoren |
US6310060B1 (en) * | 1998-06-24 | 2001-10-30 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
JP2000212141A (ja) * | 1999-01-13 | 2000-08-02 | Warner Lambert Co | ジアリ―ルアミン |
JP2000273041A (ja) * | 1999-01-19 | 2000-10-03 | Sankyo Co Ltd | グルタミン酸細胞毒性による神経細胞死の阻害剤 |
DE60014603T2 (de) * | 1999-03-12 | 2006-02-16 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Heterocyklischer harnstoff und verwandte verbindungen als entzündungshemmende mittel |
US6136835A (en) * | 1999-05-17 | 2000-10-24 | The Procter & Gamble Company | Methods of treatment for viral infections |
JP3854154B2 (ja) * | 2000-04-19 | 2006-12-06 | ニューロテック カンパニー リミテッド | 中枢神経系の急性及び慢性的損傷に起因した神経変性を防止するための化合物、組成物及び方法 |
US6964982B2 (en) * | 2000-04-20 | 2005-11-15 | Neurotech Co., Ltd. | Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system |
CN101041626B (zh) * | 2002-06-19 | 2010-08-25 | 艾克尔制药公司 | 四氟苄基衍生物及含有其成分的药物组合物 |
FR2841556B1 (fr) * | 2002-07-01 | 2007-07-20 | Centre Nat Rech Scient | Peptides ayant des proprietes antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments |
KR100522188B1 (ko) * | 2003-01-20 | 2005-10-18 | 주식회사 뉴로테크 | 뉴로트로핀에 의해 유도되는 세포괴사 억제 방법 |
-
2003
- 2003-06-19 CN CN2007100008003A patent/CN101041626B/zh not_active Expired - Lifetime
- 2003-06-19 WO PCT/KR2003/001205 patent/WO2004000786A1/en active Application Filing
- 2003-06-19 EP EP03738707.3A patent/EP1551793B1/en not_active Expired - Lifetime
- 2003-06-19 US US10/481,648 patent/US6927303B2/en not_active Expired - Lifetime
- 2003-06-19 ES ES03738707.3T patent/ES2568491T3/es not_active Expired - Lifetime
- 2003-06-19 CA CA2490120A patent/CA2490120C/en not_active Expired - Lifetime
- 2003-06-19 AU AU2003245070A patent/AU2003245070C1/en not_active Expired
- 2003-06-19 KR KR1020030039918A patent/KR100545745B1/ko active IP Right Grant
- 2003-06-19 CN CNB038167522A patent/CN1309703C/zh not_active Expired - Lifetime
- 2003-06-19 DK DK03738707.3T patent/DK1551793T3/en active
- 2003-06-19 JP JP2004515217A patent/JP4113957B2/ja not_active Expired - Lifetime
-
2005
- 2005-06-22 US US11/165,293 patent/US7189878B2/en not_active Expired - Lifetime
- 2005-10-18 KR KR1020050098051A patent/KR20050105433A/ko not_active Application Discontinuation
-
2006
- 2006-01-10 HK HK06100367.9A patent/HK1077808A1/zh not_active IP Right Cessation
- 2006-06-08 US US11/450,596 patent/US7371896B2/en not_active Expired - Lifetime
- 2006-11-22 US US11/603,653 patent/US7319160B2/en not_active Expired - Lifetime
-
2008
- 2008-03-11 US US12/075,487 patent/US7511074B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN101041626B (zh) | 2010-08-25 |
ES2568491T3 (es) | 2016-04-29 |
CN101041626A (zh) | 2007-09-26 |
US7371896B2 (en) | 2008-05-13 |
US6927303B2 (en) | 2005-08-09 |
KR20050105433A (ko) | 2005-11-04 |
DK1551793T3 (en) | 2016-04-25 |
WO2004000786A1 (en) | 2003-12-31 |
EP1551793A1 (en) | 2005-07-13 |
EP1551793A4 (en) | 2007-04-04 |
US7319160B2 (en) | 2008-01-15 |
CA2490120C (en) | 2010-06-01 |
US20080227859A1 (en) | 2008-09-18 |
KR100545745B1 (ko) | 2006-01-24 |
EP1551793B1 (en) | 2016-01-20 |
CA2490120A1 (en) | 2003-12-31 |
CN1668576A (zh) | 2005-09-14 |
US20050239896A1 (en) | 2005-10-27 |
JP4113957B2 (ja) | 2008-07-09 |
CN1309703C (zh) | 2007-04-11 |
AU2003245070C1 (en) | 2008-02-28 |
AU2003245070A1 (en) | 2004-01-06 |
JP2005529972A (ja) | 2005-10-06 |
US20060235239A1 (en) | 2006-10-19 |
US20040209957A1 (en) | 2004-10-21 |
US20070078183A1 (en) | 2007-04-05 |
US7511074B2 (en) | 2009-03-31 |
KR20030097706A (ko) | 2003-12-31 |
US7189878B2 (en) | 2007-03-13 |
AU2003245070B2 (en) | 2007-08-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1077808A1 (zh) | 四氟芐衍生物及內含同類項目以預防和治療中樞神經系統中急性與慢性神經退化疾病的醫藥成份 | |
EP1471909A4 (en) | PHARMACEUTICAL COMPOSITION AND METHOD FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | |
IL175539A0 (en) | Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions | |
ZA200407813B (en) | Medicament for preventing and/or treating chronic rejection. | |
IL231142A0 (en) | Dictopiperazine compounds and pharmaceutical preparations containing them for the treatment of t-cell mediated diseases | |
TWI346558B (en) | Pharmaceutical composition for chronic treatment of inflammation and use thereof | |
ZA200506240B (en) | Coated particles and pharmaceutical dosage forms | |
IL165532A (en) | History of Aryl Carbonyl, Pharmaceutical Preparations Containing Them and Their Use in the Preparation of Medicines for the Treatment of Metabolic Disorders | |
HUP0103856A3 (en) | Pharmaceutical composition for the treatment of acute disorders | |
HUP0302997A3 (en) | Phenylalanine derivatives with alpha4-integrin effect, pharmaceutical compositions containing them and their use | |
AU4060599A (en) | Pharmaceutical composition for treating or preventing sleep disorders | |
IL178775A (en) | Pharmaceuticals containing glucocorticoid for use in the treatment of disorders requiring acute glucocorticoid therapy | |
HK1082249A1 (en) | Isoquinoline derivatives having kinasae inhibitoryactivity and drugs containing the same | |
NZ514813A (en) | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders | |
PL377791A1 (pl) | Pochodne 3-aminopiperydyny i sposoby ich wytwarzania | |
EP1603548A4 (en) | COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS | |
IL165986A0 (en) | Isoquinoline and quinazoline derivatives and pharmaceutical compositions containing the same | |
ZA200410211B (en) | Quinuclidine derivatives and pharmaceutical compositions containing the same. | |
HUP0303264A3 (en) | Carbamate compounds for use in preventing and treating neurodegenerative disorders | |
EP1567198A4 (en) | MATERIALS AND METHOD FOR THE TREATMENT OF EYE DISEASES | |
IL191289A (en) | Pharmaceuticals containing metitrone and benzodiazepine and their use in the preparation of a drug for the treatment of neuropsychiatric disorders | |
IL162743A0 (en) | Tricyclic 2-pyrimidone derivatives and pharmaceutical compositions containing the same | |
IL155853A0 (en) | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | |
PL363869A1 (en) | Medicines for the prevention and treatment of neurodegenerative diseases | |
AU2003291730A8 (en) | Methods and compositions for treating neurodegenerative diseases |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |
Effective date: 20230618 |