HK1069845A1 - Methods of increasing endogenous erythropoietin (epo) - Google Patents

Methods of increasing endogenous erythropoietin (epo)

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Publication number
HK1069845A1
HK1069845A1 HK05101852.0A HK05101852A HK1069845A1 HK 1069845 A1 HK1069845 A1 HK 1069845A1 HK 05101852 A HK05101852 A HK 05101852A HK 1069845 A1 HK1069845 A1 HK 1069845A1
Authority
HK
Hong Kong
Prior art keywords
methods
epo
endogenous erythropoietin
increasing endogenous
hif
Prior art date
Application number
HK05101852.0A
Other languages
English (en)
Inventor
Stephen J Klaus
Al Y Lin
Thomas B Neff
Qingjian Wang
Volkmar Guenzler-Pukall
Michael P Arend
Lee A Flippin
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27502557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1069845(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of HK1069845A1 publication Critical patent/HK1069845A1/xx

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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/746Erythropoetin

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  • Gastroenterology & Hepatology (AREA)
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  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
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HK05101852.0A 2001-12-06 2005-03-03 Methods of increasing endogenous erythropoietin (epo) HK1069845A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33708201P 2001-12-06 2001-12-06
US34965902P 2002-01-16 2002-01-16
US35968302P 2002-02-25 2002-02-25
US38648802P 2002-06-05 2002-06-05
PCT/US2002/039163 WO2003053997A2 (en) 2001-12-06 2002-12-06 Methods of increasing endogenous erythropoietin (epo)

Publications (1)

Publication Number Publication Date
HK1069845A1 true HK1069845A1 (en) 2005-06-03

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HK05101852.0A HK1069845A1 (en) 2001-12-06 2005-03-03 Methods of increasing endogenous erythropoietin (epo)

Country Status (13)

Country Link
US (15) US20030153503A1 (de)
EP (7) EP2289531B1 (de)
JP (5) JP5341293B2 (de)
CN (7) CN102526044A (de)
AU (3) AU2002362065B2 (de)
CA (4) CA3094774A1 (de)
DK (3) DK1463823T3 (de)
ES (3) ES2686626T3 (de)
HK (1) HK1069845A1 (de)
HU (1) HU229475B1 (de)
IL (2) IL162085A0 (de)
NO (1) NO343732B1 (de)
WO (2) WO2003053997A2 (de)

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CA3094774A1 (en) * 2001-12-06 2003-07-03 Fibrogen, Inc. Use of hif prolyl hydroxylase inhibitors for treating neurological disorders
US8318703B2 (en) 2001-12-06 2012-11-27 Fibrogen, Inc. Methods for improving kidney function
EP2295060B1 (de) 2001-12-06 2018-10-31 Fibrogen, Inc. Behandlung ischämischer oder hypoxischer Zustände
US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US7618940B2 (en) 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
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US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
US20060251638A1 (en) * 2003-06-06 2006-11-09 Volkmar Guenzler-Pukall Cytoprotection through the use of hif hydroxylase inhibitors
US20070042937A1 (en) * 2003-08-01 2007-02-22 Fibrogen, Inc. Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers
WO2005034929A2 (en) * 2003-10-10 2005-04-21 Fibrogen, Inc. Tissue remodeling and vascularization
US20050170019A1 (en) * 2003-10-22 2005-08-04 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
US20050136125A1 (en) * 2003-10-22 2005-06-23 Roth Mark B. Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
AU2004285468B2 (en) * 2003-10-22 2011-02-24 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
US7248843B2 (en) * 2003-11-07 2007-07-24 Ge Medical Systems Information Technologies, Inc. Antenna selection system and method
EP1548031A1 (de) * 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Naturidentischer Erythropoietin
US20050282751A1 (en) * 2004-03-19 2005-12-22 Ajinomoto Co., Inc. Therapeutic agent for renal anemia
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